A family knockout of all four Drosophila metallothioneins reveals a central role in copper homeostasis and detoxification.
about
De novo assembly and analysis of changes in the protein-coding transcriptome of the freshwater shrimp Paratya australiensis (Decapoda: Atyidae) in response to acid sulfate drainage water.Tetrahymena metallothioneins fall into two discrete subfamilies.Dumpy-30 family members as determinants of male fertility and interaction partners of metal-responsive transcription factor 1 (MTF-1) in Drosophila.dRecQ4 is required for DNA synthesis and essential for cell proliferation in Drosophila.Functional studies of Drosophila zinc transporters reveal the mechanism for dietary zinc absorption and regulation.Sub-lethal metal stress response of larvae of Aedes aegypti.Shaping mechanisms of metal specificity in a family of metazoan metallothioneins: evolutionary differentiation of mollusc metallothioneinsDrosophila histone deacetylase 6 protects dopaminergic neurons against {alpha}-synuclein toxicity by promoting inclusion formation.The parkin mutant phenotype in the fly is largely rescued by metal-responsive transcription factor (MTF-1)Conserved metallomics in two insect families evolving separately for a hundred million years.Transcriptome response to heavy metal stress in Drosophila reveals a new zinc transporter that confers resistance to zincTwo metallothionein genes in Oxya chinensis: molecular characteristics, expression patterns and roles in heavy metal stress.Differential expression of metallothionein isoforms in terrestrial snail embryos reflects early life stage adaptation to metal stressCopper homeostasis in Drosophila by complex interplay of import, storage and behavioral avoidance.Physiological, Diurnal and Stress-Related Variability of Cadmium-Metallothionein Gene Expression in Land Snails.Efficient metal-specific transcription activation by Drosophila MTF-1 requires conserved cysteine residues in the carboxy-terminal domain.Homeostatic mechanisms for iron storage revealed by genetic manipulations and live imaging of Drosophila ferritinFunctional studies of Drosophila zinc transporters reveal the mechanism for zinc excretion in Malpighian tubules.Copper sensing function of Drosophila metal-responsive transcription factor-1 is mediated by a tetranuclear Cu(I) cluster.Variations in hepatic biomarkers in American alligators (Alligator mississippiensis) from three sites in Florida, USA.A recessive X-linked mutation causes a threefold reduction of total body zinc accumulation in Drosophila melanogaster laboratory strains.Huntington disease arises from a combinatory toxicity of polyglutamine and copper binding.Genetical toxicogenomics in Drosophila identifies master-modulatory loci that are regulated by developmental exposure to leadNatural and laboratory mutations in kuzbanian are associated with zinc stress phenotypes in Drosophila melanogaster.Comparative Investigation of Copper Tolerance and Identification of Putative Tolerance Related Genes in Tardigrades.The role of metallothionein in oxidative stressWhat can flies tell us about copper homeostasis?A role for the Drosophila zinc transporter Zip88E in protecting against dietary zinc toxicity.Genes of the antioxidant system of the honey bee: annotation and phylogeny.Drosophila RecQ5 is required for efficient SSA repair and suppression of LOH in vivo.Vacuolar-type H(+)-ATPase subunits and the neurogenic protein big brain are required for optimal copper and zinc uptake.Characterization of MtnE, the fifth metallothionein member in Drosophila.Distorted copper homeostasis with decreased sensitivity to cisplatin upon chaperone Atox1 deletion in Drosophila.Zinc accumulation in heterozygous mutants of fumble, the pantothenate kinase homologue of Drosophila.Is MtnE, the fifth Drosophila metallothionein, functionally distinct from the other members of this polymorphic protein family?Mercury and cadmium trigger expression of the copper importer Ctr1B, which enables Drosophila to thrive on heavy metal-loaded food.Metal contaminant accumulation in the hive: Consequences for whole-colony health and brood production in the honey bee (Apis mellifera L.).Extreme metal adapted, knockout and knockdown strains reveal a coordinated gene expression among different Tetrahymena thermophila metallothionein isoforms.Copper and Zinc Homeostasis: Lessons from Drosophila melanogaster.Overexpression of Metallothionein-1 Modulates the Phenotype of the Tg2576 Mouse Model of Alzheimer's Disease.
P2860
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P2860
A family knockout of all four Drosophila metallothioneins reveals a central role in copper homeostasis and detoxification.
description
2006 nî lūn-bûn
@nan
2006 թուականի Մարտին հրատարակուած գիտական յօդուած
@hyw
2006 թվականի մարտին հրատարակված գիտական հոդված
@hy
2006年の論文
@ja
2006年論文
@yue
2006年論文
@zh-hant
2006年論文
@zh-hk
2006年論文
@zh-mo
2006年論文
@zh-tw
2006年论文
@wuu
name
A family knockout of all four ...... omeostasis and detoxification.
@ast
A family knockout of all four ...... omeostasis and detoxification.
@en
A family knockout of all four ...... omeostasis and detoxification.
@nl
type
label
A family knockout of all four ...... omeostasis and detoxification.
@ast
A family knockout of all four ...... omeostasis and detoxification.
@en
A family knockout of all four ...... omeostasis and detoxification.
@nl
prefLabel
A family knockout of all four ...... omeostasis and detoxification.
@ast
A family knockout of all four ...... omeostasis and detoxification.
@en
A family knockout of all four ...... omeostasis and detoxification.
@nl
P2093
P2860
P50
P1476
A family knockout of all four ...... omeostasis and detoxification.
@en
P2093
Alla Vardanyan
Anand Selvaraj
Andreas Simons
Kuppusamy Balamurugan
Oleg Georgiev
Rama Rajaram
Simone Mettler
Walter Schaffner
P2860
P304
P356
10.1128/MCB.26.6.2286-2296.2006
P407
P577
2006-03-01T00:00:00Z