The mitochondria-targeted nitroxide JP4-039 augments potentially lethal irradiation damage repair
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Mitochondria as a target in treatmentStrategies for discovery of small molecule radiation protectors and radiation mitigatorsSynthesis of analogs of the radiation mitigator JP4-039 and visualization of BODIPY derivatives in mitochondriaLarge-scale asymmetric synthesis of the bioprotective agent JP4-039 and analogsThe zebrafish--Danio rerio--is a useful model for measuring the effects of small-molecule mitigators of late effects of ionizing irradiationTwo strategies for the development of mitochondrion-targeted small molecule radiation damage mitigatorsAntioxidant-chemoprevention diet ameliorates late effects of total-body irradiation and supplements radioprotection by MnSOD-plasmid liposome administrationAntioxidant Approaches to Management of Ionizing Irradiation InjuryCan Radiosensitivity Associated with Defects in DNA Repair be Overcome by Mitochondrial-Targeted Antioxidant RadioprotectorsAllylic Amines as Key Building Blocks in the Synthesis of (E)-Alkene Peptide IsosteresThe impact of ionizing radiation on placental trophoblastsRadiobiologic effects of GS-nitroxide (JP4-039) on the hematopoietic syndrome.GS-nitroxide (JP4-039)-mediated radioprotection of human Fanconi anemia cell lines.Dysregulated in vitro hematopoiesis, radiosensitivity, proliferation, and osteoblastogenesis with marrow from SAMP6 mice.Intraesophageal administration of GS-nitroxide (JP4-039) protects against ionizing irradiation-induced esophagitisThe autophagy-inducing drug carbamazepine is a radiation protector and mitigator"Only a life lived for others is worth living:" Redox Signaling by Oxygenated Phospholipids in Cell Fate Decisions.Induction of TGF-β by Irradiation or Chemotherapy in Fanconi Anemia (FA) Mouse Bone Marrow Is Modulated by Small Molecule Radiation Mitigators JP4-039 and MMS350.Mitochondria-Targeted Triphenylphosphonium-Based Compounds: Syntheses, Mechanisms of Action, and Therapeutic and Diagnostic Applications.Screening of antimicrobial agents for in vitro radiation protection and mitigation capacity, including those used in supportive care regimens for bone marrow transplant recipients.Role of the esophageal vagus neural pathway in ionizing irradiation-induced seizures in nitric oxide synthase-1 homologous recombinant negative NOS1-/- mice.Fancd2 and p21 function independently in maintaining the size of hematopoietic stem and progenitor cell pool in mice.Nanoassembly of surfactants with interfacial drug-interactive motifs as tailor-designed drug carriers.An uncharged oxetanyl sulfoxide as a covalent modifier for improving aqueous solubility.A Topical Mitochondria-Targeted Redox-Cycling Nitroxide Mitigates Oxidative Stress-Induced Skin Damage.ATF4 Regulates CD4+ T Cell Immune Responses through Metabolic Reprogramming.Evaluation of Different Formulations and Routes for the Delivery of the Ionizing Radiation Mitigator GS-Nitroxide (JP4-039)
P2860
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P2860
The mitochondria-targeted nitroxide JP4-039 augments potentially lethal irradiation damage repair
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2009 nî lūn-bûn
@nan
2009 թուականի Սեպտեմբերին հրատարակուած գիտական յօդուած
@hyw
2009 թվականի սեպտեմբերին հրատարակված գիտական հոդված
@hy
2009年の論文
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2009年論文
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2009年論文
@zh-hant
2009年論文
@zh-hk
2009年論文
@zh-mo
2009年論文
@zh-tw
2009年论文
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name
The mitochondria-targeted nitr ...... thal irradiation damage repair
@ast
The mitochondria-targeted nitr ...... thal irradiation damage repair
@en
type
label
The mitochondria-targeted nitr ...... thal irradiation damage repair
@ast
The mitochondria-targeted nitr ...... thal irradiation damage repair
@en
prefLabel
The mitochondria-targeted nitr ...... thal irradiation damage repair
@ast
The mitochondria-targeted nitr ...... thal irradiation damage repair
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P2093
P2860
P1433
P1476
The mitochondria-targeted nitr ...... thal irradiation damage repair
@en
P2093
Anthony J Kanai
Darcy Franicola
Joel S Greenberger
Joshua G Pierce
Kanika Gupta
Malolan S Rajagopalan
Michael W Epperly
Peter Wipf
Valerian E Kagan
P2860
P304
P50
P577
2009-09-01T00:00:00Z