Activity of gemifloxacin against penicillin- and ciprofloxacin-resistant Streptococcus pneumoniae displaying topoisomerase- and efflux-mediated resistance mechanisms.
about
A comparative In vitro surveillance study of gemifloxacin activities against 2,632 recent Streptococcus pneumoniae isolates from across Europe, North America, and South America. The Gemifloxacin Surveillance Study Research GroupIntracellular penetration and activity of gemifloxacin in human polymorphonuclear leukocytes.Genetic analyses of mutations contributing to fluoroquinolone resistance in clinical isolates of Streptococcus pneumoniaeTopoisomerase targeting with and resistance to gemifloxacin in Staphylococcus aureusTreatment of community-acquired pneumonia, with special emphasis on gemifloxacin.Potent antipneumococcal activity of gemifloxacin is associated with dual targeting of gyrase and topoisomerase IV, an in vivo target preference for gyrase, and enhanced stabilization of cleavable complexes in vitro.Cleavable-complex formation by wild-type and quinolone-resistant Streptococcus pneumoniae type II topoisomerases mediated by gemifloxacin and other fluoroquinolones.Accumulation of 10 fluoroquinolones by wild-type or efflux mutant Streptococcus pneumoniae.Probing the differential interactions of quinazolinedione PD 0305970 and quinolones with gyrase and topoisomerase IVActivity of gemifloxacin against quinolone-resistant Streptococcus pneumoniae strains in vitro and in a mouse pneumonia model.
P2860
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P2860
Activity of gemifloxacin against penicillin- and ciprofloxacin-resistant Streptococcus pneumoniae displaying topoisomerase- and efflux-mediated resistance mechanisms.
description
1999 nî lūn-bûn
@nan
1999 թուականի Դեկտեմբերին հրատարակուած գիտական յօդուած
@hyw
1999 թվականի դեկտեմբերին հրատարակված գիտական հոդված
@hy
1999年の論文
@ja
1999年論文
@yue
1999年論文
@zh-hant
1999年論文
@zh-hk
1999年論文
@zh-mo
1999年論文
@zh-tw
1999年论文
@wuu
name
Activity of gemifloxacin again ...... ediated resistance mechanisms.
@ast
Activity of gemifloxacin again ...... ediated resistance mechanisms.
@en
type
label
Activity of gemifloxacin again ...... ediated resistance mechanisms.
@ast
Activity of gemifloxacin again ...... ediated resistance mechanisms.
@en
prefLabel
Activity of gemifloxacin again ...... ediated resistance mechanisms.
@ast
Activity of gemifloxacin again ...... ediated resistance mechanisms.
@en
P2093
P2860
P1476
Activity of gemifloxacin again ...... ediated resistance mechanisms.
@en
P2093
Goldsmith CE
P2860
P304
P407
P577
1999-12-01T00:00:00Z