Cell-surface residence of sphingosine 1-phosphate receptor 1 on lymphocytes determines lymphocyte egress kinetics. - Wikidata - awgldk - TriplyDB

Cell-surface residence of sphingosine 1-phosphate receptor 1 on lymphocytes determines lymphocyte egress kinetics.

Cell-surface residence of sphingosine 1-phosphate receptor 1 on lymphocytes determines lymphocyte egress kinetics.

http://www.wikidata.org/entity/Q33979875

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Actions of a picomolar short-acting S1P₁ agonist in S1P₁-eGFP knock-in mice The SphKs/S1P/S1PR1 axis in immunity and cancer: more ore to be mined Sphingosine-1-phosphate receptor 1 signalling in T cells: trafficking and beyond Fingolimod for the treatment of neurological diseases-state of play and future perspectives Moesin controls clathrin-mediated S1PR1 internalization in T cells Preclinical Metabolism, Pharmacokinetics and In Vivo Analysis of New Blood-Brain-Barrier Penetrant Fingolimod Analogues: FTY720-C2 and FTY720-Mitoxy Sphingosine-1-phosphate receptor 1 in classical Hodgkin lymphoma: assessment of expression and role in cell migration.Defective sphingosine 1-phosphate receptor 1 (S1P1) phosphorylation exacerbates TH17-mediated autoimmune neuroinflammation Sphingosine 1-phosphate signaling in bone remodeling: multifaceted roles and therapeutic potential FTY720 (s)-phosphonate preserves sphingosine 1-phosphate receptor 1 expression and exhibits superior barrier protection to FTY720 in acute lung injury.The sphingosine 1-phosphate transporter, SPNS2, functions as a transporter of the phosphorylated form of the immunomodulating agent FTY720.Multiple-dose tolerability, pharmacokinetics, and pharmacodynamics of ponesimod, an S1P1 receptor modulator: favorable impact of dose up-titration.Effect of ponesimod, a selective S1P1 receptor modulator, on the QT interval in healthy individuals.Sphingosine-1-phosphate and immune regulation: trafficking and beyond Ozanimod (RPC1063) is a potent sphingosine-1-phosphate receptor-1 (S1P1 ) and receptor-5 (S1P5 ) agonist with autoimmune disease-modifying activity.Individual variation of human S1P₁ coding sequence leads to heterogeneity in receptor function and drug interactions FTY720 inhibits tubulointerstitial inflammation in albumin overload-induced nephropathy of rats via the Sphk1 pathway.S1PR1 Tyr143 phosphorylation downregulates endothelial cell surface S1PR1 expression and responsiveness.Pharmacological relevance and potential of sphingosine 1-phosphate in the vascular system.Tumor-suppressive sphingosine-1-phosphate receptor-2 counteracting tumor-promoting sphingosine-1-phosphate receptor-1 and sphingosine kinase 1 - Jekyll Hidden behind Hyde Sphingolipid and glycosphingolipid metabolic pathways in the era of sphingolipidomics.Emerging biology of sphingosine-1-phosphate: its role in pathogenesis and therapy.Regulation of mammalian physiology, development, and disease by the sphingosine 1-phosphate and lysophosphatidic acid receptors.Cbl-b-deficient mice express alterations in trafficking-related molecules but retain sensitivity to the multiple sclerosis therapeutic agent, FTY720.Visualizing S1P-directed cellular egress by intravital imaging Lymph node B lymphocyte trafficking is constrained by anatomy and highly dependent upon chemoattractant desensitization.Biocomparison of Three Formulations of the S1P1 Receptor Modulator Ponesimod in Healthy Subjects.HDL-bound sphingosine-1-phosphate restrains lymphopoiesis and neuroinflammation.Regulation of acute graft-versus-host disease by microRNA-155.The outs and the ins of sphingosine-1-phosphate in immunity Intravital Two-Photon Imaging of Lymphocytes Crossing High Endothelial Venules and Cortical Lymphatics in the Inguinal Lymph Node.The sphingosine-1-phosphate analogue FTY720 impairs mucosal immunity and clearance of the enteric pathogen Citrobacter rodentium.Communication between host organism and cancer cells is transduced by systemic sphingosine kinase 1/sphingosine 1-phosphate signalling to regulate tumour metastasis.S1P and the birth of platelets.T cell-intrinsic S1PR1 regulates endogenous effector T-cell egress dynamics from lymph nodes during infection.S1P₁ localizes to the colonic vasculature in ulcerative colitis and maintains blood vessel integrity.Fine-tuning S1P therapeutics Bioactive lipids and cationic antimicrobial peptides as new potential regulators for trafficking of bone marrow-derived stem cells in patients with acute myocardial infarction.Mechanism of Action and Clinical Potential of Fingolimod for the Treatment of Stroke.Therapeutic dosing of fingolimod (FTY720) prevents cell infiltration, rapidly suppresses ocular inflammation, and maintains the blood-ocular barrier.

P2860

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P2860

Cell-surface residence of sphingosine 1-phosphate receptor 1 on lymphocytes determines lymphocyte egress kinetics.

http://www.wikidata.org/entity/Q33979875

description

2010 nî lūn-bûn

@nan

2010 թուականի Յունիսին հրատարակուած գիտական յօդուած

@hyw

2010 թվականի հունիսին հրատարակված գիտական հոդված

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2010年の論文

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2010年論文

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2010年論文

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2010年論文

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2010年論文

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2010年論文

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2010年论文

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name

Cell-surface residence of sphi ...... es lymphocyte egress kinetics.

@ast

Cell-surface residence of sphi ...... es lymphocyte egress kinetics.

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type

label

Cell-surface residence of sphi ...... es lymphocyte egress kinetics.

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Cell-surface residence of sphi ...... es lymphocyte egress kinetics.

@en

prefLabel

Cell-surface residence of sphi ...... es lymphocyte egress kinetics.

@ast

Cell-surface residence of sphi ...... es lymphocyte egress kinetics.

@en

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Cell-surface residence of sphi ...... es lymphocyte egress kinetics.

@en

P2093

Caiying Guo

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Dong-Soon Im

http://www.w3.org/2001/XMLSchema#string

Kamal M Khanna

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Leo Lefrancois

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Myat Lin Oo

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Shobha Thangada

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Timothy Hla

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Victoria A Blaho

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P2860

S1P1 receptor signaling overrides retention mediated by G alpha i-coupled receptors to promote T cell egress

Ligand-induced trafficking of the sphingosine-1-phosphate receptor EDG-1

Oral fingolimod or intramuscular interferon for relapsing multiple sclerosis

Sphingosine-1-phosphate lyase in immunity and cancer: silencing the siren

Expression of the sphingosine 1-phosphate receptor, S1P1, on T-cells controls thymic emigration

Sphingosine-1-phosphate mobilizes osteoclast precursors and regulates bone homeostasis

Sphingosine 1-phosphate receptors

A highly efficient recombineering-based method for generating conditional knockout mutations

Alteration of lymphocyte trafficking by sphingosine-1-phosphate receptor agonists

Lymphocyte egress from thymus and peripheral lymphoid organs is dependent on S1P receptor 1

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1475-1483

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10.1084/JEM.20091343

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7

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207

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20584883

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