Exogenous control of mammalian gene expression through modulation of RNA self-cleavage.
about
Yeast transcripts cleaved by an internal ribozyme provide new insight into the role of the cap and poly(A) tail in translation and mRNA decayInhibition of polyadenylation reduces inflammatory gene inductionIdentification of Toyocamycin, an agent cytotoxic for multiple myeloma cells, as a potent inhibitor of ER stress-induced XBP1 mRNA splicingA discontinuous hammerhead ribozyme embedded in a mammalian messenger RNATailoring RNA modular units on a common scaffold: a modular ribozyme with a catalytic unit for beta-nicotinamide mononucleotide-activated RNA ligationA Panel of Protease-Responsive RNA Polymerases Respond to Biochemical Signals by Production of Defined RNA Outputs in Live CellsTracking, tuning, and terminating microbial physiology using synthetic riboregulators.Identification of inhibitors of ribozyme self-cleavage in mammalian cells via high-throughput screening of chemical libraries.Screening helix-threading peptides for RNA binding using a thiazole orange displacement assayDesign principles for ligand-sensing, conformation-switching ribozymes.Eukaryotic systems broaden the scope of synthetic biology.Synthetic strategies for studying embryonic development.Activation and deactivation of DNAzyme and antisense function with light for the photochemical regulation of gene expression in mammalian cellsAptazyme-embedded guide RNAs enable ligand-responsive genome editing and transcriptional activation.Synthetic biology: applications come of ageEvaluating target silencing by short hairpin RNA mediated by the group I intron in cultured mammalian cellsGene knockdowns in adult animals: PPMOs and vivo-morpholinos.Artificial riboswitches for gene expression and replication control of DNA and RNA viruses.Riboswitch-mediated Attenuation of Transgene Cytotoxicity Increases Adeno-associated Virus Vector Yields in HEK-293 Cells.Development of a regulatable oncolytic herpes simplex virus type 1 recombinant virus for tumor therapy.Protein and RNA engineering to customize microbial molecular reporting.Computational analysis of riboswitch-based regulationSuccessful production of pseudotyped rAAV vectors using a modified baculovirus expression system.Directing cellular information flow via CRISPR signal conductors.Extraordinary rates of transition metal ion-mediated ribozyme catalysisA general design strategy for protein-responsive riboswitches in mammalian cells.Distinct reaction pathway promoted by non-divalent-metal cations in a tertiary stabilized hammerhead ribozyme.A modular and extensible RNA-based gene-regulatory platform for engineering cellular functionRiboswitching on RNA virus replicationGene therapy for obesity.Gene therapy for Parkinson's disease using recombinant adeno-associated viral vectors.Gene therapy progress and prospects--vectorology: design and production of expression cassettes in AAV vectors.Synthetic riboswitches for external regulation of genes transferred by replication-deficient and oncolytic adenoviruses.RNA synthetic biology.Synthetic RNA circuits.Synthetic circuits, devices and modules.RNA as a versatile and powerful platform for engineering genetic regulatory tools.An adaptable system for improving transposon-based gene expression in vivo via transient transgene repression.Principles and applications of the photochemical control of cellular processes.Mapping the human protein interactome.
P2860
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P2860
Exogenous control of mammalian gene expression through modulation of RNA self-cleavage.
description
2004 nî lūn-bûn
@nan
2004 թուականի Սեպտեմբերին հրատարակուած գիտական յօդուած
@hyw
2004 թվականի սեպտեմբերին հրատարակված գիտական հոդված
@hy
2004年の論文
@ja
2004年論文
@yue
2004年論文
@zh-hant
2004年論文
@zh-hk
2004年論文
@zh-mo
2004年論文
@zh-tw
2004年论文
@wuu
name
Exogenous control of mammalian gene expression through modulation of RNA self-cleavage.
@ast
Exogenous control of mammalian gene expression through modulation of RNA self-cleavage.
@en
type
label
Exogenous control of mammalian gene expression through modulation of RNA self-cleavage.
@ast
Exogenous control of mammalian gene expression through modulation of RNA self-cleavage.
@en
prefLabel
Exogenous control of mammalian gene expression through modulation of RNA self-cleavage.
@ast
Exogenous control of mammalian gene expression through modulation of RNA self-cleavage.
@en
P2093
P356
P1433
P1476
Exogenous control of mammalian gene expression through modulation of RNA self-cleavage.
@en
P2093
Jeng-Shin Lee
Jennifer Svendsen
John T Gray
Laising Yen
Maxime Magnier
Richard C Mulligan
Robert J D'Amato
Takashi Baba
P2888
P304
P356
10.1038/NATURE02844
P407
P577
2004-09-01T00:00:00Z
P6179
1018979204