Predicting inactive conformations of protein kinases using active structures: conformational selection of type-II inhibitors.

Predicting inactive conformations of protein kinases using active structures: conformational selection of type-II inhibitors.

Item
http://www.wikidata.org/entity/Q33983328
Exploration of type II binding mode: A privileged approach for kinase inhibitor focused drug discovery?Recent Progress in the Molecular Recognition and Therapeutic Importance of Interleukin-1 Receptor-Associated Kinase 4In silico 3D structure modeling and inhibitor binding studies of human male germ cell-associated kinase.Insights into molecular interactions between CaM and its inhibitors from molecular dynamics simulations and experimental data.Promiscuous and specific recognition among ephrins and Eph receptorsDiscovery of tyrosine kinase inhibitors by docking into an inactive kinase conformation generated by molecular dynamics.DFGmodel: predicting protein kinase structures in inactive states for structure-based discovery of type-II inhibitorsCan structural features of kinase receptors provide clues on selectivity and inhibition? A molecular modeling studyAccurate calculation of mutational effects on the thermodynamics of inhibitor binding to p38α MAP kinase: a combined computational and experimental studyFrom Type I to Type II: Design, Synthesis, and Characterization of Potent Pyrazin-2-ones as DFG-Out Inhibitors of PDGFRβ.PL-PatchSurfer2: Improved Local Surface Matching-Based Virtual Screening Method That Is Tolerant to Target and Ligand Structure Variation.Redefining the Protein Kinase Conformational Space with Machine Learning.
P2860

Predicting inactive conformations of protein kinases using active structures: conformational selection of type-II inhibitors.

Item
http://www.wikidata.org/entity/Q33983328
description
2011 nî lūn-bûn
@nan
2011 թուականի Յուլիսին հրատարակուած գիտական յօդուած
@hyw
2011 թվականի հուլիսին հրատարակված գիտական հոդված
@hy
2011年の論文
@ja
2011年論文
@yue
2011年論文
@zh-hant
2011年論文
@zh-hk
2011年論文
@zh-mo
2011年論文
@zh-tw
2011年论文
@wuu
name
Predicting inactive conformati ...... lection of type-II inhibitors.
@ast
Predicting inactive conformati ...... lection of type-II inhibitors.
@en
type
label
Predicting inactive conformati ...... lection of type-II inhibitors.
@ast
Predicting inactive conformati ...... lection of type-II inhibitors.
@en
prefLabel
Predicting inactive conformati ...... lection of type-II inhibitors.
@ast
Predicting inactive conformati ...... lection of type-II inhibitors.
@en
P1433
P1476
P2093
P2860
P304
P31
P356
P407
P433
P478
P577
P5875
P698
P932
P356
P1433
P1476
Predicting inactive conformati ...... lection of type-II inhibitors.
@en
P2093
P2860
P304
P31
P356
10.1371/JOURNAL.PONE.0022644
P407
P433
P478
P577
P5875
P698
P932