Structural basis for the autoinhibition of c-Abl tyrosine kinase
about
Identification and functional analysis of a new phosphorylation site (Y398) in the SH3 domain of Abi-1Trafficking of Lyn through the Golgi caveolin involves the charged residues on alphaE and alphaI helices in the kinase domainThe unique N-terminal region of SRMS regulates enzymatic activity and phosphorylation of its novel substrate docking protein 1A Salmonella type III secretion effector interacts with the mammalian serine/threonine protein kinase PKN1c-Abl tyrosine kinase interacts with MAVS and regulates innate immune responseAllosteric inhibition of the nonMyristoylated c-Abl tyrosine kinase by phosphopeptides derived from Abi1/Hssh3bp1Type IV secretion in the obligatory intracellular bacterium Anaplasma phagocytophilumStructural coupling of SH2-kinase domains links Fes and Abl substrate recognition and kinase activationRegulation of cell migration and morphogenesis by Abl-family kinases: emerging mechanisms and physiological contextsA conserved protonation-dependent switch controls drug binding in the Abl kinaseCrystal structure of 12-oxophytodienoate reductase 3 from tomato: self-inhibition by dimerizationStructural basis for the autoinhibition of focal adhesion kinaseGleevec inhibits beta-amyloid production but not Notch cleavageThe Philadelphia chromosome in leukemogenesisMultifunctional Abl kinases in health and diseaseThe growing arsenal of ATP-competitive and allosteric inhibitors of BCR-ABLStructural biology contributions to the discovery of drugs to treat chronic myelogenous leukaemiaEntropic switch regulates myristate exposure in the HIV-1 matrix proteinXIAP Induces NF-κB Activation via the BIR1/TAB1 Interaction and BIR1 DimerizationActivation of tyrosine kinases by mutation of the gatekeeper threonineCrystal Structures of the FAK Kinase in Complex with TAE226 and Related Bis-Anilino Pyrimidine Inhibitors Reveal a Helical DFG ConformationThe structure of the leukemia drug imatinib bound to human quinone reductase 2 (NQO2)Equally Potent Inhibition of c-Src and Abl by Compounds that Recognize Inactive Kinase ConformationsRole of Interfacial Water Molecules in Proline-rich Ligand Recognition by the Src Homology 3 Domain of AblTargeting Bcr–Abl by combining allosteric with ATP-binding-site inhibitorsA potent and highly specific FN3 monobody inhibitor of the Abl SH2 domainStructures of apicomplexan calcium-dependent protein kinases reveal mechanism of activation by calciumCrystal Structure of the Src Family Kinase Hck SH3-SH2 Linker Regulatory Region Supports an SH3-dominant Activation MechanismCoupling of receptor conformation and ligand orientation determine graded activityCrystal Structures of ABL-Related Gene (ABL2) in Complex with Imatinib, Tozasertib (VX-680), and a Type I Inhibitor of the Triazole Carbothioamide ClassConformational Control Inhibition of the BCR-ABL1 Tyrosine Kinase, Including the Gatekeeper T315I Mutant, by the Switch-Control Inhibitor DCC-2036The Structure of Myristoylated Mason-Pfizer Monkey Virus Matrix Protein and the Role of Phosphatidylinositol-(4,5)-Bisphosphate in Its Membrane BindingATPase-dependent role of the atypical kinase Rio2 on the evolving pre-40S ribosomal subunitTargeting the SH2-Kinase Interface in Bcr-Abl Inhibits LeukemogenesisAck1: Activation and Regulation by AllosteryStructural and Spectroscopic Analysis of the Kinase Inhibitor Bosutinib and an Isomer of Bosutinib Binding to the Abl Tyrosine Kinase DomainRole of N-Terminal Myristylation in the Structure and Regulation of cAMP-Dependent Protein KinaseTwo Amino Acid Residues Confer Different Binding Affinities of Abelson Family Kinase Src Homology 2 Domains for Phosphorylated CortactinFGFR1 Kinase Inhibitors: Close Regioisomers Adopt Divergent Binding Modes and Display Distinct Biophysical SignaturesStructural basis for the inhibition of Polo-like kinase 1
P2860
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P2860
Structural basis for the autoinhibition of c-Abl tyrosine kinase
description
2003 nî lūn-bûn
@nan
2003 թուականի Մարտին հրատարակուած գիտական յօդուած
@hyw
2003 թվականի մարտին հրատարակված գիտական հոդված
@hy
2003年の論文
@ja
2003年論文
@yue
2003年論文
@zh-hant
2003年論文
@zh-hk
2003年論文
@zh-mo
2003年論文
@zh-tw
2003年论文
@wuu
name
Structural basis for the autoinhibition of c-Abl tyrosine kinase
@ast
Structural basis for the autoinhibition of c-Abl tyrosine kinase
@en
Structural basis for the autoinhibition of c-Abl tyrosine kinase
@nl
type
label
Structural basis for the autoinhibition of c-Abl tyrosine kinase
@ast
Structural basis for the autoinhibition of c-Abl tyrosine kinase
@en
Structural basis for the autoinhibition of c-Abl tyrosine kinase
@nl
prefLabel
Structural basis for the autoinhibition of c-Abl tyrosine kinase
@ast
Structural basis for the autoinhibition of c-Abl tyrosine kinase
@en
Structural basis for the autoinhibition of c-Abl tyrosine kinase
@nl
P2093
P50
P3181
P1433
P1476
Structural basis for the autoinhibition of c-Abl tyrosine kinase
@en
P2093
Bayard Clarkson
Bhushan Nagar
Darren Veach
William Bornmann
P304
P3181
P356
10.1016/S0092-8674(03)00194-6
P407
P577
2003-03-21T00:00:00Z