Antibody humanization: a case of the 'Emperor's new clothes'?
about
Specific genetic modifications of domestic animals by gene targeting and animal cloningBeyond humanization and de-immunization: tolerization as a method for reducing the immunogenicity of biologicsThermodynamic consequences of mutations in vernier zone residues of a humanized anti-human epidermal growth factor receptor murine antibody, 528Characterization of IgG1 conformation and conformational dynamics by hydrogen/deuterium exchange mass spectrometryIncidence, Prevention and Management of Anti-Drug Antibodies Against Therapeutic Antibodies in Inflammatory Bowel Disease: A Practical Overview.Humanized antibody neutralizing 2009 pandemic H1N1 virus.Antibody humanization by structure-based computational protein design.Immunogenicity of mAbs in non-human primates during nonclinical safety assessmentUsing simple artificial intelligence methods for predicting amyloidogenesis in antibodiesFlow-cytometric isolation of human antibodies from a nonimmune Saccharomyces cerevisiae surface display library.Production of a human single-chain variable fragment antibody against esophageal carcinomaIdentification of an antibody fragment specific for androgen-dependent prostate cancer cells.New approaches in the treatment of asthma.Prediction and analysis of antibody amyloidogenesis from sequences.Development of Next-Generation Peptide Binders Using In vitro Display Technologies and Their Potential Applications.Rebmab200, a humanized monoclonal antibody targeting the sodium phosphate transporter NaPi2b displays strong immune mediated cytotoxicity against cancer: a novel reagent for targeted antibody therapy of cancerOne target, different effects: a comparison of distinct therapeutic antibodies against the same targets.Understanding differences between synthetic and natural antibodies can help improve antibody engineering.Efficient expression of full-length antibodies in the cytoplasm of engineered bacteria.Opinion: antibody-based therapies for malaria.Induction of tumor-specific T cell immunity by anti-DR5 antibody therapy.Antibodies for targeted cancer therapy -- technical aspects and clinical perspectives.Engineering and characterization of a mouse/human chimeric anti-phencyclidine monoclonal antibody.Toward a new generation of vaccines: the anti-cytokine therapeutic vaccines.Drug insight: using monoclonal antibodies to treat multiple sclerosis.Engineering and characterisation of chimeric monoclonal antibody 806 (ch806) for targeted immunotherapy of tumours expressing de2-7 EGFR or amplified EGFRProduction and characterisation of a recombinant scFv reactive with human gastrointestinal carcinomas.Role of monoclonal antibodies in tumor-specific immunity.Rapid discovery and optimization of therapeutic antibodies against emerging infectious diseases.Molecular, biologic, and pharmacokinetic properties of monoclonal antibodies: impact of these parameters on early clinical development.Antibody Therapeutics in Oncology.Possible therapeutic applications of single-chain antibodies in systemic autoimmune diseases.Targeting nanomedicines in the treatment of Crohn's disease: focus on certolizumab pegol (CDP870).Structure based antibody-like peptidomimetics.Overview of cell-based tools for pre-clinical assessment of immunogenicity of biotherapeutics.Antibody engineering to develop new antirheumatic therapies.Cancer therapy with trifunctional antibodies: linking innate and adaptive immunity.Preclinical development of therapeutic biologics.The effect of antidrug antibodies on the sustainable efficacy of biologic therapies in rheumatoid arthritis: practical consequences.Tocilizumab, a humanized anti-IL-6R antibody, as an emerging therapeutic option for rheumatoid arthritis: molecular and cellular mechanistic insights.
P2860
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P2860
Antibody humanization: a case of the 'Emperor's new clothes'?
description
2000 nî lūn-bûn
@nan
2000 թուականի Օգոստոսին հրատարակուած գիտական յօդուած
@hyw
2000 թվականի օգոստոսին հրատարակված գիտական հոդված
@hy
2000年の論文
@ja
2000年論文
@yue
2000年論文
@zh-hant
2000年論文
@zh-hk
2000年論文
@zh-mo
2000年論文
@zh-tw
2000年论文
@wuu
name
Antibody humanization: a case of the 'Emperor's new clothes'?
@ast
Antibody humanization: a case of the 'Emperor's new clothes'?
@en
type
label
Antibody humanization: a case of the 'Emperor's new clothes'?
@ast
Antibody humanization: a case of the 'Emperor's new clothes'?
@en
prefLabel
Antibody humanization: a case of the 'Emperor's new clothes'?
@ast
Antibody humanization: a case of the 'Emperor's new clothes'?
@en
P1433
P1476
Antibody humanization: a case of the 'Emperor's new clothes'?
@en
P2093
P304
P356
10.1016/S0167-5699(00)01680-7
P577
2000-08-01T00:00:00Z