Vaccinia virus H3L envelope protein is a major target of neutralizing antibodies in humans and elicits protection against lethal challenge in mice. - Wikidata - awgldk - TriplyDB

Vaccinia virus H3L envelope protein is a major target of neutralizing antibodies in humans and elicits protection against lethal challenge in mice.

Vaccinia virus H3L envelope protein is a major target of neutralizing antibodies in humans and elicits protection against lethal challenge in mice.

http://www.wikidata.org/entity/Q33987410

about

From functional genomics to functional immunomics: new challenges, old problems, big rewards Smallpox vaccines for biodefense: need and feasibility New approaches to understanding the immune response to vaccination and infection Side-by-side comparison of gene-based smallpox vaccine with MVA in nonhuman primates Structural basis for the binding of the neutralizing antibody, 7D11, to the poxvirus L1 protein Structural and Biochemical Characterization of the Vaccinia Virus Envelope Protein D8 and Its Recognition by the Antibody LA5 Allergic airway disease in mice alters T and B cell responses during an acute respiratory poxvirus infection A protein-based smallpox vaccine protects mice from vaccinia and ectromelia virus challenges when given as a prime and single boost.Mining, visualizing and comparing multidimensional biomolecular data using the Genomics Data Miner (GMine) Web-Server.Human CD4+ T cell epitopes from vaccinia virus induced by vaccination or infection New classes of orthopoxvirus vaccine candidates by functionally screening a synthetic library for protective antigens.Progress towards recombinant anti-infective antibodies.Human antibody responses to the polyclonal Dryvax vaccine for smallpox prevention can be distinguished from responses to the monoclonal replacement vaccine ACAM2000.Evaluation of smallpox vaccines using variola neutralization.Genome-wide profiling of humoral immune response to Coxiella burnetii infection by protein microarray.Combination therapy of vaccinia virus infection with human anti-H3 and anti-B5 monoclonal antibodies in a small animal model.High-throughput profiling of the humoral immune responses against thirteen human papillomavirus types by proteome microarrays.The neutralizing antibody response to the vaccinia virus A28 protein is specifically enhanced by its association with the H2 protein The impact of "omic" and imaging technologies on assessing the host immune response to biodefence agents.Evaluating the orthopoxvirus type I interferon-binding molecule as a vaccine target in the vaccinia virus intranasal murine challenge model.Plasmodium immunomics.Vaccinia virus proteome: identification of proteins in vaccinia virus intracellular mature virion particles.Therapeutic Vaccines and Antibodies for Treatment of Orthopoxvirus Infections.Protection of rabbits and immunodeficient mice against lethal poxvirus infections by human monoclonal antibodies.Safety and immunogenicity of modified vaccinia Ankara (ACAM3000): effect of dose and route of administration.Identification of immunodominant antigens by probing a whole Chlamydia trachomatis open reading frame proteome microarray using sera from immunized mice.Capturing the natural diversity of the human antibody response against vaccinia virus The Vaccinia virus complement control protein modulates adaptive immune responses during infection Human immune responses to Burkholderia pseudomallei characterized by protein microarray analysis.Smallpox vaccines: targets of protective immunity.Multivalent smallpox DNA vaccine delivered by intradermal electroporation drives protective immunity in nonhuman primates against lethal monkeypox challenge.B cell-specific expression of B7-2 is required for follicular Th cell function in response to vaccinia virus.Protein microarrays: high-throughput tools for proteomics.Human T-cell responses to vaccinia virus envelope proteins.An epitope conserved in orthopoxvirus A13 envelope protein is the target of neutralizing and protective antibodies Passive immunotherapies protect WRvFire and IHD-J-Luc vaccinia virus-infected mice from lethality by reducing viral loads in the upper respiratory tract and internal organs T cell antigen discovery using soluble vaccinia proteome reveals recognition of antigens with both virion and nonvirion association.Preferential replication of vaccinia virus in the ovaries is independent of immune regulation through IL-10 and TGF-β Polyclonal antibody cocktails generated using DNA vaccine technology protect in murine models of orthopoxvirus disease.A High Throughput Protein Microarray Approach to Classify HIV Monoclonal Antibodies and Variant Antigens.

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Vaccinia virus H3L envelope protein is a major target of neutralizing antibodies in humans and elicits protection against lethal challenge in mice.

http://www.wikidata.org/entity/Q33987410

description

2005 nî lūn-bûn

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2005 թուականի Սեպտեմբերին հրատարակուած գիտական յօդուած

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2005 թվականի սեպտեմբերին հրատարակված գիտական հոդված

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2005年の論文

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2005年論文

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2005年論文

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2005年論文

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2005年論文

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2005年论文

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Vaccinia virus H3L envelope pr ...... inst lethal challenge in mice.

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Vaccinia virus H3L envelope pr ...... inst lethal challenge in mice.

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Vaccinia virus H3L envelope pr ...... inst lethal challenge in mice.

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Vaccinia virus H3L envelope pr ...... inst lethal challenge in mice.

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Vaccinia virus H3L envelope pr ...... inst lethal challenge in mice.

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Vaccinia virus H3L envelope pr ...... inst lethal challenge in mice.

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JVI.79.18.11724-11733.2005

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Journal of Virology

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Vaccinia virus H3L envelope pr ...... ainst lethal challenge in mice

@en

P2093

Conrad Valdez

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D Huw Davies

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Devan Huynh

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Jenny E Hernandez

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Luis Villarreal

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Megan M McCausland

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Philip L Felgner

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Shane Crotty

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Siddiqua Hirst

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P2860

Smallpox as a Biological Weapon

Smallpox DNA vaccine protects nonhuman primates against lethal monkeypox

Protection against lethal vaccinia virus challenge in HLA-A2 transgenic mice by immunization with a single CD8+ T-cell peptide epitope of vaccinia and variola viruses.

The reactivity of monoclonal antibodies against orf virus with other parapoxviruses and the identification of a 39 kDa immunodominant protein.

Identification of poxvirus CD8+ T cell determinants to enable rational design and characterization of smallpox vaccines

Identification and characterization of vaccinia virus genes encoding proteins that are highly antigenic in animals and are immunodominant in vaccinated humans.

Profiling the humoral immune response to infection by using proteome microarrays: high-throughput vaccine and diagnostic antigen discovery

Vaccinia virus envelope H3L protein binds to cell surface heparan sulfate and is important for intracellular mature virion morphogenesis and virus infection in vitro and in vivo

Characterization of the vaccinia virus H3L envelope protein: topology and posttranslational membrane insertion via the C-terminal hydrophobic tail

Effects of deletion or stringent repression of the H3L envelope gene on vaccinia virus replication.

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11724-11733

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10.1128/JVI.79.18.11724-11733.2005

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