Differential transcriptional activation by human T-cell leukemia virus type 1 Tax mutants is mediated by distinct interactions with CREB binding protein and p300
about
The HTLV-1 Tax interactomeMolecular cloning of a novel human I-mfa domain-containing protein that differently regulates human T-cell leukemia virus type I and HIV-1 expressionViruses associated with human cancerRole of Tax protein in human T-cell leukemia virus type-I leukemogenicityMolecular Studies of HTLV-1 Replication: An UpdateOncogenes and RNA splicing of human tumor virusesKATs in cancer: functions and therapiesCREB-binding protein (CBP)/p300 and RNA polymerase II colocalize in transcriptionally active domains in the nucleusRegulation of the human interleukin-5 promoter by Ets transcription factors. Ets1 and Ets2, but not Elf-1, cooperate with GATA3 and HTLV-I Tax1CREB--a real culprit in oncogenesisHuman T-cell leukemia virus type 1 Tax shuttles between functionally discrete subcellular targets.Adenovirus E1A requires the yeast SAGA histone acetyltransferase complex and associates with SAGA components Gcn5 and Tra1.Tax-1 and Tax-2 similarities and differences: focus on post-translational modifications and NF-κB activation.Tax oncoprotein of HTLV-1 binds to the human homologue of Drosophila discs large tumor suppressor protein, hDLG, and perturbs its function in cell growth control.MyoD stimulates RB promoter activity via the CREB/p300 nuclear transduction pathway.Distinct p300-responsive mechanisms promote caspase-dependent apoptosis by human T-cell lymphotropic virus type 1 Tax protein.Phosphorylation of the human T-cell leukemia virus type 1 transactivator tax on adjacent serine residues is critical for tax activationIn vivo rescue of a silent tax-deficient bovine leukemia virus from a tumor-derived ovine B-cell line by recombination with a retrovirally transduced wild-type tax gene.Acetylation of the human T-cell leukemia virus type 1 Tax oncoprotein by p300 promotes activation of the NF-kappaB pathway.An exposed KID-like domain in human T-cell lymphotropic virus type 1 Tax is responsible for the recruitment of coactivators CBP/p300Human T-cell leukemia virus type 2 tax mutants that selectively abrogate NFkappaB or CREB/ATF activation fail to transform primary human T cells.Genetic evidence of a role for ATM in functional interaction between human T-cell leukemia virus type 1 Tax and p53.PCAF interacts with tax and stimulates tax transactivation in a histone acetyltransferase-independent mannerMolecular interactions involved in the transactivation of the human T-cell leukemia virus type 1 promoter mediated by Tax and CREB-2 (ATF-4).Inactivation of a single copy of Crebbp selectively alters pre-mRNA processing in mouse hematopoietic stem cells.Human T-cell leukemia virus type 1 expressing nonoverlapping tax and rex genes replicates and immortalizes primary human T lymphocytes but fails to replicate and persist in vivo.Exclusive ubiquitination and sumoylation on overlapping lysine residues mediate NF-kappaB activation by the human T-cell leukemia virus tax oncoprotein.Human T-lymphotropic virus type 1 oncoprotein tax promotes S-phase entry but blocks mitosis.The four and a half LIM family members are novel interactants of the human T-cell leukemia virus type 1 Tax oncoproteinVersatile reporter systems show that transactivation by human T-cell leukemia virus type 1 Tax occurs independently of chromatin remodeling factor BRG1.Tax recruitment of CBP/p300, via the KIX domain, reveals a potent requirement for acetyltransferase activity that is chromatin dependent and histone tail independentMove or die: the fate of the Tax oncoprotein of HTLV-1.A stimulus-specific role for CREB-binding protein (CBP) in T cell receptor-activated tumor necrosis factor alpha gene expressionHTLV-1 Tax mutants that do not induce G1 arrest are disabled in activating the anaphase promoting complex.Proapoptotic regimes for HTLV-I-transformed cells: targeting Tax and the NF-kappaB pathway.Ubiquitination of HTLV-I Tax in response to DNA damage regulates nuclear complex formation and nuclear export.Ubiquitination and sumoylation of the HTLV-2 Tax-2B protein regulate its NF-κB activity: a comparative study with the HTLV-1 Tax-1 protein.Cross talk between expression of the human T-cell leukemia virus type 1 Tax transactivator and the oncogenic bHLH transcription factor TAL1.Acetylation at lysine 346 controls the transforming activity of the HTLV-1 Tax oncoprotein in the Rat-1 fibroblast modelHTLV-1 and apoptosis: role in cellular transformation and recent advances in therapeutic approaches.
P2860
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P2860
Differential transcriptional activation by human T-cell leukemia virus type 1 Tax mutants is mediated by distinct interactions with CREB binding protein and p300
description
1998 nî lūn-bûn
@nan
1998 թուականի Ապրիլին հրատարակուած գիտական յօդուած
@hyw
1998 թվականի ապրիլին հրատարակված գիտական հոդված
@hy
1998年の論文
@ja
1998年論文
@yue
1998年論文
@zh-hant
1998年論文
@zh-hk
1998年論文
@zh-mo
1998年論文
@zh-tw
1998年论文
@wuu
name
Differential transcriptional a ...... CREB binding protein and p300
@ast
Differential transcriptional a ...... CREB binding protein and p300
@en
type
label
Differential transcriptional a ...... CREB binding protein and p300
@ast
Differential transcriptional a ...... CREB binding protein and p300
@en
prefLabel
Differential transcriptional a ...... CREB binding protein and p300
@ast
Differential transcriptional a ...... CREB binding protein and p300
@en
P2093
P2860
P356
P1476
Differential transcriptional a ...... CREB binding protein and p300
@en
P2093
P2860
P304
P356
10.1128/MCB.18.4.2392
P407
P577
1998-04-01T00:00:00Z