Ubiquitination of HTLV-I Tax in response to DNA damage regulates nuclear complex formation and nuclear export.
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The HTLV-1 Tax interactomeInduction of reactive oxygen species by human T-cell leukemia virus type 1 tax correlates with DNA damage and expression of cellular senescence marker.An RNA interference screen identifies the Deubiquitinase STAMBPL1 as a critical regulator of human T-cell leukemia virus type 1 tax nuclear export and NF-κB activation.The four and a half LIM family members are novel interactants of the human T-cell leukemia virus type 1 Tax oncoproteinHuman T Lymphotropic Virus Type 1 (HTLV-1): Molecular Biology and Oncogenesis.Move or die: the fate of the Tax oncoprotein of HTLV-1.C7a, a biphosphinic cyclopalladated compound, efficiently controls the development of a patient-derived xenograft model of adult T cell leukemia/lymphoma.The Sumo-targeted ubiquitin ligase RNF4 regulates the localization and function of the HTLV-1 oncoprotein Tax.Low nuclear body formation and tax SUMOylation do not prevent NF-kappaB promoter activationHTLV tax: a fascinating multifunctional co-regulator of viral and cellular pathwaysWip1 and p53 contribute to HTLV-1 Tax-induced tumorigenesisRegulation of the nucleocytoplasmic trafficking of viral and cellular proteins by ubiquitin and small ubiquitin-related modifiers.Physical and in silico approaches identify DNA-PK in a Tax DNA-damage response interactome.Dimerization and a novel Tax speckled structure localization signal are required for Tax nuclear localization.HTLV gene regulation: because size matters, transcription is not enough.Distinct functions of HTLV-1 Tax1 from HTLV-2 Tax2 contribute key roles to viral pathogenesis.Intracellular localization and cellular factors interaction of HTLV-1 and HTLV-2 Tax proteins: similarities and functional differences.The MHC-II transactivator CIITA, a restriction factor against oncogenic HTLV-1 and HTLV-2 retroviruses: similarities and differences in the inhibition of Tax-1 and Tax-2 viral transactivators.Human T-lymphotropic virus proteins and post-translational modification pathwaysRegulation of HTLV-1 tax stability, cellular trafficking and NF-κB activation by the ubiquitin-proteasome pathway.The Major Histocompatibility Complex Class II Transactivator CIITA Inhibits the Persistent Activation of NF-κB by the Human T Cell Lymphotropic Virus Type 1 Tax-1 Oncoprotein.Human T cell leukemia virus type 2 tax-mediated NF-κB activation involves a mechanism independent of Tax conjugation to ubiquitin and SUMO.
P2860
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P2860
Ubiquitination of HTLV-I Tax in response to DNA damage regulates nuclear complex formation and nuclear export.
description
2007 nî lūn-bûn
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2007年の論文
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2007年学术文章
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2007年学术文章
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2007年学术文章
@zh-hans
2007年学术文章
@zh-my
2007年学术文章
@zh-sg
2007年學術文章
@yue
2007年學術文章
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2007年學術文章
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name
Ubiquitination of HTLV-I Tax i ...... formation and nuclear export.
@ast
Ubiquitination of HTLV-I Tax i ...... formation and nuclear export.
@en
type
label
Ubiquitination of HTLV-I Tax i ...... formation and nuclear export.
@ast
Ubiquitination of HTLV-I Tax i ...... formation and nuclear export.
@en
prefLabel
Ubiquitination of HTLV-I Tax i ...... formation and nuclear export.
@ast
Ubiquitination of HTLV-I Tax i ...... formation and nuclear export.
@en
P2093
P2860
P921
P356
P1433
P1476
Ubiquitination of HTLV-I Tax i ...... formation and nuclear export.
@en
P2093
Michael L Gatza
Susan J Marriott
Tajhal Dayaram
P2860
P2888
P356
10.1186/1742-4690-4-95
P577
2007-12-14T00:00:00Z
P5875
P6179
1030268640