PLCzeta, a sperm-specific PLC and its potential role in fertilization.
about
Novel regulation of PLCζ activity via its XY-linkerParthenogenetic activation of bovine oocytes using bovine and murine phospholipase C zeta.Oocyte activation, phospholipase C zeta and human infertility.Human PLCζ exhibits superior fertilization potency over mouse PLCζ in triggering the Ca(2+) oscillations required for mammalian oocyte activationGenome-wide association study identifies phospholipase C zeta 1 (PLCz1) as a stallion fertility locus in Hanoverian warmblood horsesArtificial activation of bovine and equine oocytes with cycloheximide, roscovitine, strontium, or 6-dimethylaminopurine in low or high calcium concentrations.The roles of Ca2+, downstream protein kinases, and oscillatory signaling in regulating fertilization and the activation of development.Phospholipase Cζ binding to PtdIns(4,5)P2 requires the XY-linker regionMale infertility-linked point mutation disrupts the Ca2+ oscillation-inducing and PIP(2) hydrolysis activity of sperm PLCζ.Loss of activity mutations in phospholipase C zeta (PLCζ) abolishes calcium oscillatory ability of human recombinant protein in mouse oocytes.A maternally inherited autosomal point mutation in human phospholipase C zeta (PLCζ) leads to male infertilityOocyte activation and phospholipase C zeta (PLCζ): diagnostic and therapeutic implications for assisted reproductive technology.Signal transduction in mammalian oocytes during fertilization.Fluorescent phosphatidylinositol 4,5-bisphosphate derivatives with modified 6-hydroxy group as novel substrates for phospholipase C.Calcium signalling in early embryos.Chimeras of sperm PLCζ reveal disparate protein domain functions in the generation of intracellular Ca2+ oscillations in mammalian eggs at fertilization.Starting a new life: sperm PLC-zeta mobilizes the Ca2+ signal that induces egg activation and embryo development: an essential phospholipase C with implications for male infertility.Comparative biology of sperm factors and fertilization-induced calcium signals across the animal kingdom.Egg Activation at Fertilization.Successful fertilization and embryo development after spermatid injection: A hope for nonobstructive azoospermic patientsIdentifying organisms.
P2860
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P2860
PLCzeta, a sperm-specific PLC and its potential role in fertilization.
description
2007 nî lūn-bûn
@nan
2007 թուականի Յունուարին հրատարակուած գիտական յօդուած
@hyw
2007 թվականի հունվարին հրատարակված գիտական հոդված
@hy
2007年の論文
@ja
2007年論文
@yue
2007年論文
@zh-hant
2007年論文
@zh-hk
2007年論文
@zh-mo
2007年論文
@zh-tw
2007年论文
@wuu
name
PLCzeta, a sperm-specific PLC and its potential role in fertilization.
@ast
PLCzeta, a sperm-specific PLC and its potential role in fertilization.
@en
PLCzeta, a sperm-specific PLC and its potential role in fertilization.
@nl
type
label
PLCzeta, a sperm-specific PLC and its potential role in fertilization.
@ast
PLCzeta, a sperm-specific PLC and its potential role in fertilization.
@en
PLCzeta, a sperm-specific PLC and its potential role in fertilization.
@nl
prefLabel
PLCzeta, a sperm-specific PLC and its potential role in fertilization.
@ast
PLCzeta, a sperm-specific PLC and its potential role in fertilization.
@en
PLCzeta, a sperm-specific PLC and its potential role in fertilization.
@nl
P2093
P356
P1476
PLCzeta, a sperm-specific PLC and its potential role in fertilization.
@en
P2093
Christopher M Saunders
F Anthony Lai
Karl Swann
P356
10.1042/BSS0740023
P577
2007-01-01T00:00:00Z