Effects of base polymer hydrophobicity and end-group modification on polymeric gene delivery
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Novel delivery strategies for glioblastomaGene delivery polymer structure-function relationships elucidated via principal component analysis.Uptake and transfection with polymeric nanoparticles are dependent on polymer end-group structure, but largely independent of nanoparticle physical and chemical properties.Differential polymer structure tunes mechanism of cellular uptake and transfection routes of poly(β-amino ester) polyplexes in human breast cancer cellsBiodegradable polymeric nanoparticles show high efficacy and specificity at DNA delivery to human glioblastoma in vitro and in vivoHybrid biosynthetic gene therapy vector development and dual engineering capacity.Gene delivery nanoparticles specific for human microvasculature and macrovasculature.2011 Rita Schaffer lecture: nanoparticles for intracellular nucleic acid delivery.Poly(β-amino ester)-nanoparticle mediated transfection of retinal pigment epithelial cells in vitro and in vivo.Development of poly(β-amino ester)-based biodegradable nanoparticles for nonviral delivery of minicircle DNA.Evaluating the potential of poly(beta-amino ester) nanoparticles for reprogramming human fibroblasts to become induced pluripotent stem cellsPolymeric nanoparticles for nonviral gene therapy extend brain tumor survival in vivo.Novel cationic triblock copolymer of poly[2-(dimethylamino)ethyl methacrylate]-block-poly(β-amino ester)-block-poly[2-(dimethylamino)ethyl methacrylate]: a promising non-viral gene delivery system.Synthetic poly(ester amine) and poly(amido amine) nanoparticles for efficient DNA and siRNA delivery to human endothelial cellsCystamine-terminated poly(beta-amino ester)s for siRNA delivery to human mesenchymal stem cells and enhancement of osteogenic differentiation.Dual-imaging enabled cancer-targeting nanoparticles.Combinatorial optimization of PEG architecture and hydrophobic content improves ternary siRNA polyplex stability, pharmacokinetics, and potency in vivo.Poly(β-amino ester) nanoparticle delivery of TP53 has activity against small cell lung cancer in vitro and in vivo.A nonviral pHEMA+chitosan nanosphere-mediated high-efficiency gene delivery systemNanoparticle-mediated conversion of primary human astrocytes into neurons and oligodendrocytes(3-aminopropyl)-4-methylpiperazine end-capped poly(1,4-butanediol diacrylate-co-4-amino-1-butanol)-based multilayer films for gene delivery.The effect and role of carbon atoms in poly(β-amino ester)s for DNA binding and gene delivery.Programming stem cells for therapeutic angiogenesis using biodegradable polymeric nanoparticles.Bioreducible cationic polymer-based nanoparticles for efficient and environmentally triggered cytoplasmic siRNA delivery to primary human brain cancer cells.Bioreducible Poly(Beta-Amino Ester)s for Intracellular Delivery of SiRNA.Engineered polymeric amphiphiles self-assembling into nanostructures and acting as efficient gene and drug carriers.Polymeric nanoparticles as cancer-specific DNA delivery vectors to human hepatocellular carcinoma.Miniaturization of gene transfection assays in 384- and 1536-well microplates.Continuous microfluidic assembly of biodegradable poly(beta-amino ester)/DNA nanoparticles for enhanced gene delivery.Hydrophobic interactions between polymeric carrier and palmitic acid-conjugated siRNA improve PEGylated polyplex stability and enhance in vivo pharmacokinetics and tumor gene silencingA Triple-Fluorophore-Labeled Nucleic Acid pH Nanosensor to Investigate Non-viral Gene Delivery.Effects of trehalose polycation end-group functionalization on plasmid DNA uptake and transfection.Reducible Disulfide Poly(beta-amino ester) Hydrogels for Antioxidant Delivery.Biodegradable STING agonist nanoparticles for enhanced cancer immunotherapy.
P2860
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P2860
Effects of base polymer hydrophobicity and end-group modification on polymeric gene delivery
description
2011 nî lūn-bûn
@nan
2011 թուականի Սեպտեմբերին հրատարակուած գիտական յօդուած
@hyw
2011 թվականի սեպտեմբերին հրատարակված գիտական հոդված
@hy
2011年の論文
@ja
2011年論文
@yue
2011年論文
@zh-hant
2011年論文
@zh-hk
2011年論文
@zh-mo
2011年論文
@zh-tw
2011年论文
@wuu
name
Effects of base polymer hydrop ...... ion on polymeric gene delivery
@ast
Effects of base polymer hydrop ...... ion on polymeric gene delivery
@en
Effects of base polymer hydrop ...... ion on polymeric gene delivery
@nl
type
label
Effects of base polymer hydrop ...... ion on polymeric gene delivery
@ast
Effects of base polymer hydrop ...... ion on polymeric gene delivery
@en
Effects of base polymer hydrop ...... ion on polymeric gene delivery
@nl
prefLabel
Effects of base polymer hydrop ...... ion on polymeric gene delivery
@ast
Effects of base polymer hydrop ...... ion on polymeric gene delivery
@en
Effects of base polymer hydrop ...... ion on polymeric gene delivery
@nl
P2093
P2860
P356
P1433
P1476
Effects of base polymer hydrop ...... ion on polymeric gene delivery
@en
P2093
Kristen L Kozielski
Marib I Akanda
P2860
P304
P356
10.1021/BM200807S
P577
2011-09-09T00:00:00Z