Age-associated mitochondrial oxidative decay: improvement of carnitine acetyltransferase substrate-binding affinity and activity in brain by feeding old rats acetyl-L- carnitine and/or R-alpha -lipoic acid.

Age-associated mitochondrial oxidative decay: improvement of carnitine acetyltransferase substrate-binding affinity and activity in brain by feeding old rats acetyl-L- carnitine and/or R-alpha -lipoic acid.

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http://www.wikidata.org/entity/Q34011426

Q34011426

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Alpha lipoic acid for dementia Memory loss in old rats is associated with brain mitochondrial decay and RNA/DNA oxidation: partial reversal by feeding acetyl-L-carnitine and/or R-alpha -lipoic acid Abnormally low serum acylcarnitine levels in narcolepsy patients Novel therapeutics for Alzheimer's disease: an update Killing Me Softly: Connotations to Unfolded Protein Response and Oxidative Stress in Alzheimer's Disease Mitochondrial dysfunction in inflammatory bowel disease Biology of ageing and role of dietary antioxidants Metabolic disturbances in diseases with neurological involvement Neuronal failure in Alzheimer's disease: a view through the oxidative stress looking-glass Effects of age, dietary, and behavioral enrichment on brain mitochondria in a canine model of human aging Iron behaving badly: inappropriate iron chelation as a major contributor to the aetiology of vascular and other progressive inflammatory and degenerative diseases Translating the basic knowledge of mitochondrial functions to metabolic therapy: role of L-carnitine Targeting neuroprotection as an alternative approach to preventing and treating neuropathic pain Loss of taste responds to high-dose biotin treatment.Acetyl L-carnitine protects motor neurons and Rohon-Beard sensory neurons against ketamine-induced neurotoxicity in zebrafish embryos.The mitochondrial DNA polymerase as a target of oxidative damage.Are ancient proteins responsible for the age-related decline in health and fitness?Mitochondria in the elderly: Is acetylcarnitine a rejuvenator?Feeding acetyl-L-carnitine and lipoic acid to old rats significantly improves metabolic function while decreasing oxidative stress.Mitochondrial dynamics in Alzheimer's disease: opportunities for future treatment strategies.Prevention of mutation, cancer, and other age-associated diseases by optimizing micronutrient intake.An enthusiasm for metabolism.Decline in transcriptional activity of Nrf2 causes age-related loss of glutathione synthesis, which is reversible with lipoic acid.Age-dependent modulation of synaptic plasticity and insulin mimetic effect of lipoic acid on a mouse model of Alzheimer's disease.Increasing longevity by tuning up metabolism. To maximize human health and lifespan, scientists must abandon outdated models of micronutrients.PPAR-γ regulates carnitine homeostasis and mitochondrial function in a lamb model of increased pulmonary blood flow Energy restriction and potential energy restriction mimetics.Low micronutrient intake may accelerate the degenerative diseases of aging through allocation of scarce micronutrients by triage Delaying brain mitochondrial decay and aging with mitochondrial antioxidants and metabolites.Frontiers in Alzheimer's disease therapeutics.Nitric oxide and mitochondria in metabolic syndrome.Antioxidants in the canine model of human aging.Mitochondrial Dysfunction during Brain Aging: Role of Oxidative Stress and Modulation by Antioxidant Supplementation.Iron accumulation during cellular senescence in human fibroblasts in vitro In vivo imaging of axonal transport of mitochondria in the diseased and aged mammalian CNS.Reducing mitochondrial decay with mitochondrial nutrients to delay and treat cognitive dysfunction, Alzheimer's disease, and Parkinson's disease.(R)-alpha-lipoic acid reverses the age-related loss in GSH redox status in post-mitotic tissues: evidence for increased cysteine requirement for GSH synthesis.A placebo-controlled trial of acetyl-L-carnitine and α-lipoic acid in the treatment of bipolar depression The mitochondrial energy transduction system and the aging process.The role of mitochondria in aging

P2860

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P2860

Age-associated mitochondrial oxidative decay: improvement of carnitine acetyltransferase substrate-binding affinity and activity in brain by feeding old rats acetyl-L- carnitine and/or R-alpha -lipoic acid.

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http://www.wikidata.org/entity/Q34011426

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2002 nî lūn-bûn

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2002 թուականի Փետրուարին հրատարակուած գիտական յօդուած

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2002 թվականի փետրվարին հրատարակված գիտական հոդված

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2002年の論文

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