The transcriptional landscape of mouse beta cells compared to human beta cells reveals notable species differences in long non-coding RNA and protein-coding gene expression.
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Insulin-secreting β cells require a post-genomic conceptLong Noncoding RNAs: A New Regulatory Code in Metabolic ControlA 3D map of the islet routes throughout the healthy human pancreas.Osteopontin activates the diabetes-associated potassium channel TALK-1 in pancreatic β-cells.A comparative analysis of human and mouse islet G-protein coupled receptor expression.Research Resource: A Dual Proteomic Approach Identifies Regulated Islet Proteins During β-Cell Mass Expansion In Vivo.Opposing effects of prostaglandin E2 receptors EP3 and EP4 on mouse and human β-cell survival and proliferationRestoration of Lepr in β cells of Lepr null mice does not prevent hyperinsulinemia and hyperglycemiaReversal of β cell de-differentiation by a small molecule inhibitor of the TGFβ pathway.Urocortin3 mediates somatostatin-dependent negative feedback control of insulin secretionTASK-1 Potassium Channels Limit Pancreatic α-Cell Calcium Influx and Glucagon Secretion.A live-cell, high-content imaging survey of 206 endogenous factors across five stress conditions reveals context-dependent survival effects in mouse primary beta cells.Differential cell autonomous responses determine the outcome of coxsackievirus infections in murine pancreatic α and β cellsAugmented Stat5 Signaling Bypasses Multiple Impediments to Lactogen-Mediated Proliferation in Human β-Cells.Transcriptome analysis of pancreatic cells across distant species highlights novel important regulator genes.Pancreatic β cell enhancers regulate rhythmic transcription of genes controlling insulin secretionThe two pore channel TPC2 is dispensable in pancreatic β-cells for normal Ca²⁺ dynamics and insulin secretion.Single-cell transcriptomes reveal characteristic features of human pancreatic islet cell typesSirtuin 6 regulates glucose-stimulated insulin secretion in mouse pancreatic beta cellsAge-Dependent Pancreatic Gene Regulation Reveals Mechanisms Governing Human β Cell Function.Beta cell adaptation in pregnancy: a tribute to Claes Hellerström.Comprehensive alpha, beta and delta cell transcriptomes reveal that ghrelin selectively activates delta cells and promotes somatostatin release from pancreatic islets.Changes in the expression of the type 2 diabetes-associated gene VPS13C in the β-cell are associated with glucose intolerance in humans and mice.Insights from lncRNAs Profiling of MIN6 Beta Cells Undergoing Inflammation.Single-Cell Transcriptome Profiling of Human Pancreatic Islets in Health and Type 2 Diabetes.A Single-Cell Transcriptome Atlas of the Human Pancreas.A Single-Cell Transcriptomic Map of the Human and Mouse Pancreas Reveals Inter- and Intra-cell Population Structure.Human Pancreatic β Cell lncRNAs Control Cell-Specific Regulatory Networks.Analysis of Purified Pancreatic Islet Beta and Alpha Cell Transcriptomes Reveals 11β-Hydroxysteroid Dehydrogenase (Hsd11b1) as a Novel Disallowed Gene.Role of transcription factors in the transdifferentiation of pancreatic islet cells.Epigenetic modifications and long noncoding RNAs influence pancreas development and function.Genes affecting β-cell function in type 1 diabetes.A Whole-Genome RNA Interference Screen Reveals a Role for Spry2 in Insulin Transcription and the Unfolded Protein Response.The CRF family of neuropeptides and their receptors - mediators of the central stress response.Serotonin competence of mouse beta cells during pregnancy.Pseudotemporal Ordering of Single Cells Reveals Metabolic Control of Postnatal β Cell Proliferation.Early sympathetic islet neuropathy in autoimmune diabetes: lessons learned and opportunities for investigation.Pancreatic α- and β-cellular clocks have distinct molecular properties and impact on islet hormone secretion and gene expression.Role of long non-coding RNAs in the determination of β-cell identity.β-Cell dysfunction in diabetes: a crisis of identity?
P2860
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P2860
The transcriptional landscape of mouse beta cells compared to human beta cells reveals notable species differences in long non-coding RNA and protein-coding gene expression.
description
2014 nî lūn-bûn
@nan
2014 թուականի Յուլիսին հրատարակուած գիտական յօդուած
@hyw
2014 թվականի հուլիսին հրատարակված գիտական հոդված
@hy
2014年の論文
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2014年学术文章
@wuu
2014年学术文章
@zh-cn
2014年学术文章
@zh-hans
2014年学术文章
@zh-my
2014年学术文章
@zh-sg
2014年學術文章
@yue
name
The transcriptional landscape ...... rotein-coding gene expression.
@ast
The transcriptional landscape ...... rotein-coding gene expression.
@en
The transcriptional landscape ...... rotein-coding gene expression.
@nl
type
label
The transcriptional landscape ...... rotein-coding gene expression.
@ast
The transcriptional landscape ...... rotein-coding gene expression.
@en
The transcriptional landscape ...... rotein-coding gene expression.
@nl
prefLabel
The transcriptional landscape ...... rotein-coding gene expression.
@ast
The transcriptional landscape ...... rotein-coding gene expression.
@en
The transcriptional landscape ...... rotein-coding gene expression.
@nl
P2093
P2860
P50
P356
P1433
P1476
The transcriptional landscape ...... protein-coding gene expression
@en
P2093
Cynthia J Donaldson
Kristof Tigyi
Talitha van der Meulen
P2860
P356
10.1186/1471-2164-15-620
P407
P577
2014-07-22T00:00:00Z