Mannose 6-phosphate receptor-mediated transport of sulfamidase across the blood-brain barrier in the newborn mouse.
about
Protein replacement therapy partially corrects the cholesterol-storage phenotype in a mouse model of Niemann-Pick type C2 diseaseReplacing the enzyme alpha-L-iduronidase at birth ameliorates symptoms in the brain and periphery of dogs with mucopolysaccharidosis type I.Characteristics of compounds that cross the blood-brain barrierGenistein reduces glycosaminoglycan levels in a mouse model of mucopolysaccharidosis type IIMouse models of neurological disorders: a view from the blood-brain barrier.Insulin receptor antibody-sulfamidase fusion protein penetrates the primate blood-brain barrier and reduces glycosoaminoglycans in Sanfilippo type A cells.Agile delivery of protein therapeutics to CNSHuman immunodeficiency virus-1 uses the mannose-6-phosphate receptor to cross the blood-brain barrierSystemic administration of tripeptidyl peptidase I in a mouse model of late infantile neuronal ceroid lipofuscinosis: effect of glycan modification.Lysosomal storage disease: gene therapy on both sides of the blood-brain barrier.Gene therapy for the nervous system: challenges and new strategies.Liver production of sulfamidase reverses peripheral and ameliorates CNS pathology in mucopolysaccharidosis IIIA mice.Alpha Adrenergic Induction of Transport of Lysosomal Enzyme across the Blood-Brain Barrier.Barrier mechanisms in the developing brain.Intravenous high-dose enzyme replacement therapy with recombinant palmitoyl-protein thioesterase reduces visceral lysosomal storage and modestly prolongs survival in a preclinical mouse model of infantile neuronal ceroid lipofuscinosis.Biochemical evidence for superior correction of neuronal storage by chemically modified enzyme in murine mucopolysaccharidosis VII.Chronic enzyme replacement therapy ameliorates neuropathology in alpha-mannosidosis micePharmacologic manipulation of lysosomal enzyme transport across the blood-brain barrier.The final frontier -- crossing the blood-brain barrier.A highly secreted sulphamidase engineered to cross the blood-brain barrier corrects brain lesions of mice with mucopolysaccharidoses type IIIA.Strategies for delivery of therapeutics into the central nervous system for treatment of lysosomal storage disorders.New biotechnological and nanomedicine strategies for treatment of lysosomal storage disordersEmerging therapies for neurodegenerative lysosomal storage disorders - from concept to reality.Improving the transport of chemotherapeutic drugs across the blood-brain barrier.Biophysical characterization of lectin-glycan interactions for therapeutics, vaccines and targeted drug-delivery.Lysosomal enzyme replacement therapies: Historical development, clinical outcomes, and future perspectives.Insulin-Like Growth Factor-II/Cation-Independent Mannose 6-Phosphate Receptor in Neurodegenerative Diseases.Widespread biochemical correction of murine mucopolysaccharidosis type VII pathology by liver hydrodynamic plasmid delivery.Guanidinylated Neomycin Conjugation Enhances Intranasal Enzyme Replacement in the Brain.Safety evaluation of chronic intrathecal administration of heparan N-sulfatase in juvenile cynomolgus monkeys.Efficacy of enzyme replacement therapy in an aggravated mouse model of metachromatic leukodystrophy declines with age.Modification of protein transfer across blood/cerebrospinal fluid barrier in response to altered plasma protein composition during development.
P2860
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P2860
Mannose 6-phosphate receptor-mediated transport of sulfamidase across the blood-brain barrier in the newborn mouse.
description
2008 nî lūn-bûn
@nan
2008 թուականի Ապրիլին հրատարակուած գիտական յօդուած
@hyw
2008 թվականի ապրիլին հրատարակված գիտական հոդված
@hy
2008年の論文
@ja
2008年論文
@yue
2008年論文
@zh-hant
2008年論文
@zh-hk
2008年論文
@zh-mo
2008年論文
@zh-tw
2008年论文
@wuu
name
Mannose 6-phosphate receptor-m ...... barrier in the newborn mouse.
@ast
Mannose 6-phosphate receptor-m ...... barrier in the newborn mouse.
@en
Mannose 6-phosphate receptor-m ...... barrier in the newborn mouse.
@nl
type
label
Mannose 6-phosphate receptor-m ...... barrier in the newborn mouse.
@ast
Mannose 6-phosphate receptor-m ...... barrier in the newborn mouse.
@en
Mannose 6-phosphate receptor-m ...... barrier in the newborn mouse.
@nl
prefLabel
Mannose 6-phosphate receptor-m ...... barrier in the newborn mouse.
@ast
Mannose 6-phosphate receptor-m ...... barrier in the newborn mouse.
@en
Mannose 6-phosphate receptor-m ...... barrier in the newborn mouse.
@nl
P2093
P2860
P356
P1433
P1476
Mannose 6-phosphate receptor-m ...... barrier in the newborn mouse.
@en
P2093
Akihiko Urayama
Jeffrey H Grubb
William S Sly
P2860
P304
P356
10.1038/MT.2008.84
P577
2008-04-29T00:00:00Z