The antitumor histone deacetylase inhibitor suberoylanilide hydroxamic acid exhibits antiinflammatory properties via suppression of cytokines.
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Histone deacetylase inhibition modulates indoleamine 2,3-dioxygenase–dependent DC functions and regulates experimental graft-versus-host disease in miceThe histone deacetylase inhibitor Trichostatin A modulates CD4+ T cell responsesHistone deacetylase inhibitors modulate metalloproteinase gene expression in chondrocytes and block cartilage resorptionHDAC Inhibitors as Epigenetic Regulators of the Immune System: Impacts on Cancer Therapy and Inflammatory DiseasesHistone deacetylases in monocyte/macrophage development, activation and metabolism: refining HDAC targets for inflammatory and infectious diseasesNovel immunotherapeutic approaches for the treatment of acute leukemia (myeloid and lymphoblastic)Epigenetic Modulators of Monocytic Function: Implication for Steady State and Disease in the CNSHistone Modifications, Modifiers and Readers in Melanoma Resistance to Targeted and Immune TherapyHDAC inhibitors and immunotherapy; a double edged sword?Histone deacetylases as targets for treatment of multiple diseasesCurrent and emerging strategies for the prevention of graft-versus-host diseaseHistone deacetylase inhibitors impair the elimination of HIV-infected cells by cytotoxic T-lymphocytesHDACi Valproic Acid (VPA) and Suberoylanilide Hydroxamic Acid (SAHA) Delay but Fail to Protect against Warm Hepatic Ischemia-Reperfusion InjuryHistone deacetylase 3 (HDAC 3) as emerging drug target in NF-κB-mediated inflammationHistone deacetylase 7 promotes Toll-like receptor 4-dependent proinflammatory gene expression in macrophagesGenetics and epigenetics of rheumatoid arthritisHistone deacetylases 1 and 3 but not 2 mediate cytokine-induced beta cell apoptosis in INS-1 cells and dispersed primary islets from rats and are differentially regulated in the islets of type 1 diabetic childrenProspects for treatment of latent HIV.Neuroprotection by the histone deacetylase inhibitor trichostatin A in a model of lipopolysaccharide-sensitised neonatal hypoxic-ischaemic brain injury.Anti-leukemia activity of MS-275 histone deacetylase inhibitor implicates 4-1BBL/4-1BB immunomodulatory functions.Histone deacetylase inhibitors: a new mode for inhibition of cholesterol metabolism.Detection of gene expression in an individual cell type within a cell mixture using microarray analysis.Vorinostat plus tacrolimus and mycophenolate to prevent graft-versus-host disease after related-donor reduced-intensity conditioning allogeneic haemopoietic stem-cell transplantation: a phase 1/2 trialPleiotropic anti-myeloma activity of ITF2357: inhibition of interleukin-6 receptor signaling and repression of miR-19a and miR-19bSeparating graft-versus-leukemia from graft-versus-host disease in allogeneic hematopoietic stem cell transplantation.Transcriptome analysis revealed unique genes as targets for the anti-inflammatory action of activated protein C in human macrophages.Antifibrotic activity of an inhibitor of histone deacetylases in DOCA-salt hypertensive ratsHistone acetyltransferases are crucial regulators in NF-κB mediated inflammation.Histone Deacetylase Inhibitor M344 Inhibits Cell Proliferation and Induces Apoptosis in Human THP-1 Leukemia Cells.The histone deacetylase inhibitor, LBH589, promotes the systemic cytokine and effector responses of adoptively transferred CD8+ T cellsA novel HDAC inhibitor with a hydroxy-pyrimidine scaffoldBET bromodomain inhibition as a novel strategy for reactivation of HIV-1Histone deacetylase inhibitor-temozolomide co-treatment inhibits melanoma growth through suppression of Chemokine (C-C motif) ligand 2-driven signals.Increased activity and expression of histone deacetylase 1 in relation to tumor necrosis factor-alpha in synovial tissue of rheumatoid arthritisHelper T cell plasticity: impact of extrinsic and intrinsic signals on transcriptomes and epigenomes.Glycolysis-dependent histone deacetylase 4 degradation regulates inflammatory cytokine production.Combined treatment of adenosine nucleoside inhibitor NITD008 and histone deacetylase inhibitor vorinostat represents an immunotherapy strategy to ameliorate West Nile virus infection.The histone deacetylase inhibitor ITF2357 reduces production of pro-inflammatory cytokines in vitro and systemic inflammation in vivoDifferences in signaling pathways by IL-1beta and IL-18.Histone deacetylase inhibitors modulate renal disease in the MRL-lpr/lpr mouse.
P2860
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P2860
The antitumor histone deacetylase inhibitor suberoylanilide hydroxamic acid exhibits antiinflammatory properties via suppression of cytokines.
description
2002 nî lūn-bûn
@nan
2002 թուականի Փետրուարին հրատարակուած գիտական յօդուած
@hyw
2002 թվականի փետրվարին հրատարակված գիտական հոդված
@hy
2002年の論文
@ja
2002年論文
@yue
2002年論文
@zh-hant
2002年論文
@zh-hk
2002年論文
@zh-mo
2002年論文
@zh-tw
2002年论文
@wuu
name
The antitumor histone deacetyl ...... via suppression of cytokines.
@ast
The antitumor histone deacetyl ...... via suppression of cytokines.
@en
The antitumor histone deacetyl ...... via suppression of cytokines.
@nl
type
label
The antitumor histone deacetyl ...... via suppression of cytokines.
@ast
The antitumor histone deacetyl ...... via suppression of cytokines.
@en
The antitumor histone deacetyl ...... via suppression of cytokines.
@nl
prefLabel
The antitumor histone deacetyl ...... via suppression of cytokines.
@ast
The antitumor histone deacetyl ...... via suppression of cytokines.
@en
The antitumor histone deacetyl ...... via suppression of cytokines.
@nl
P2093
P2860
P50
P356
P1476
The antitumor histone deacetyl ...... via suppression of cytokines.
@en
P2093
Benjamin J Pomerantz
Flavio Leoni
Giancarlo Donà
Gianluca Fossati
Giorgio Bertolini
Giulia Porro
Igor Goncharov
Leonid L Reznikov
Paolo Mascagni
Paolo Pagani
P2860
P304
P356
10.1073/PNAS.052702999
P407
P577
2002-02-26T00:00:00Z