Histone deacetylase inhibitors modulate renal disease in the MRL-lpr/lpr mouse.
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Histone deacetylase inhibition modulates indoleamine 2,3-dioxygenase–dependent DC functions and regulates experimental graft-versus-host disease in micecAMP-responsive element modulator (CREM)α protein signaling mediates epigenetic remodeling of the human interleukin-2 gene: implications in systemic lupus erythematosusThe many roles of histone deacetylases in development and physiology: implications for disease and therapyHDAC Inhibitors as Epigenetic Regulators of the Immune System: Impacts on Cancer Therapy and Inflammatory DiseasesHistone deacetylases as targets for treatment of multiple diseasesSmall molecules in the treatment of systemic lupus erythematosusHistone deacetylase inhibitors impair the elimination of HIV-infected cells by cytotoxic T-lymphocytesEpigenetic Modulation as a Therapeutic Prospect for Treatment of Autoimmune Rheumatic DiseasesTrichostatin A increases SMN expression and survival in a mouse model of spinal muscular atrophy.Vorinostat plus tacrolimus and mycophenolate to prevent graft-versus-host disease after related-donor reduced-intensity conditioning allogeneic haemopoietic stem-cell transplantation: a phase 1/2 trialThe type 1 diabetes - HLA susceptibility interactome--identification of HLA genotype-specific disease genes for type 1 diabetes.Metabolic control of the epigenome in systemic Lupus erythematosus.Global H4 acetylation analysis by ChIP-chip in systemic lupus erythematosus monocytes.Pathogenic mechanisms in systemic lupus erythematosus.Oxidative stress in the pathology and treatment of systemic lupus erythematosusThe biology of reactive intermediates in systemic lupus erythematosus.The Smn-independent beneficial effects of trichostatin A on an intermediate mouse model of spinal muscular atrophy.Naja naja atra Venom Protects against Manifestations of Systemic Lupus Erythematosus in MRL/lpr MiceIncreased activity and expression of histone deacetylase 1 in relation to tumor necrosis factor-alpha in synovial tissue of rheumatoid arthritisApolipoprotein A-I modulates regulatory T cells in autoimmune LDLr-/-, ApoA-I-/- mice.Therapeutic potential of trichostatin A to control inflammatory and fibrogenic disorders of the ocular surface.Epigenetics of autoantigens: new opportunities for therapy of autoimmune diseases.The histone deacetylase inhibitor ITF2357 reduces production of pro-inflammatory cytokines in vitro and systemic inflammation in vivoMurine models of systemic lupus erythematosusEpigenetic enzymes are the therapeutic targets for CD4(+)CD25(+/high)Foxp3(+) regulatory T cellsPotential of epigenetic therapies in non-cancerous conditions.Cubilin expression is monoallelic and epigenetically augmented via PPARs.Long-term administration of the histone deacetylase inhibitor vorinostat attenuates renal injury in experimental diabetes through an endothelial nitric oxide synthase-dependent mechanismThe epigenetics of autoimmunity.Specific inhibition of histone deacetylase 8 reduces gene expression and production of proinflammatory cytokines in vitro and in vivoHistone deacetylase inhibitors for treating a spectrum of diseases not related to cancerPharmacokinetics, safety and inducible cytokine responses during a phase 1 trial of the oral histone deacetylase inhibitor ITF2357 (givinostat).HDAC inhibition in lupus models.HDAC inhibition and graft versus host diseaseHistone deacetylase regulation of immune gene expression in tumor cells.Biomarker profiling for lupus nephritis.Cardiovascular risk in systemic autoimmune diseases: epigenetic mechanisms of immune regulatory functionsT cells as a therapeutic target in SLE.Histone deacetylase 9 deficiency protects against effector T cell-mediated systemic autoimmunityHDAC inhibitor SAHA normalizes the levels of VLCFAs in human skin fibroblasts from X-ALD patients and downregulates the expression of proinflammatory cytokines in Abcd1/2-silenced mouse astrocytes.
P2860
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P2860
Histone deacetylase inhibitors modulate renal disease in the MRL-lpr/lpr mouse.
description
2003 nî lūn-bûn
@nan
2003 թուականի Փետրուարին հրատարակուած գիտական յօդուած
@hyw
2003 թվականի փետրվարին հրատարակված գիտական հոդված
@hy
2003年の論文
@ja
2003年論文
@yue
2003年論文
@zh-hant
2003年論文
@zh-hk
2003年論文
@zh-mo
2003年論文
@zh-tw
2003年论文
@wuu
name
Histone deacetylase inhibitors modulate renal disease in the MRL-lpr/lpr mouse.
@ast
Histone deacetylase inhibitors modulate renal disease in the MRL-lpr/lpr mouse.
@en
Histone deacetylase inhibitors modulate renal disease in the MRL-lpr/lpr mouse.
@nl
type
label
Histone deacetylase inhibitors modulate renal disease in the MRL-lpr/lpr mouse.
@ast
Histone deacetylase inhibitors modulate renal disease in the MRL-lpr/lpr mouse.
@en
Histone deacetylase inhibitors modulate renal disease in the MRL-lpr/lpr mouse.
@nl
prefLabel
Histone deacetylase inhibitors modulate renal disease in the MRL-lpr/lpr mouse.
@ast
Histone deacetylase inhibitors modulate renal disease in the MRL-lpr/lpr mouse.
@en
Histone deacetylase inhibitors modulate renal disease in the MRL-lpr/lpr mouse.
@nl
P2093
P2860
P1476
Histone deacetylase inhibitors modulate renal disease in the MRL-lpr/lpr mouse
@en
P2093
Christopher M Reilly
Gary S Gilkeson
Nilamadhab Mishra
P2860
P304
P356
10.1172/JCI16153
10.1172/JCI200316153
P407
P50
P577
2003-02-01T00:00:00Z