The G protein-coupled receptor kinase-2 is a TGFbeta-inducible antagonist of TGFbeta signal transduction.
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Mdm2 is involved in the ubiquitination and degradation of G-protein-coupled receptor kinase 2GRK2: multiple roles beyond G protein-coupled receptor desensitizationReversible Human TGF-β Signal Shifting between Tumor Suppression and Fibro-Carcinogenesis: Implications of Smad Phospho-Isoforms for Hepatic Epithelial-Mesenchymal TransitionsGRK2 in the heart: a GPCR kinase and beyondBreast cancer anti-estrogen resistance 3 inhibits transforming growth factor β/Smad signaling and associates with favorable breast cancer disease outcomesEngulfment protein GULP is regulator of transforming growth factor-β response in ovarian cells.G protein-coupled receptor kinase 2 (GRK2) modulation and cell cycle progressionTGF-β/Smad signaling during hepatic fibro-carcinogenesis (review).Multiple scaffolding functions of {beta}-arrestins in the degradation of G protein-coupled receptor kinase 2G protein-coupled receptor kinase 5 phosphorylation of hip regulates internalization of the chemokine receptor CXCR4Smad phosphoisoform signaling specificity: the right place at the right timeG protein-coupled receptor kinases: more than just kinases and not only for GPCRsSmad phosphoisoform signals in acute and chronic liver injury: similarities and differences between epithelial and mesenchymal cells.Regulation of Smad activities.Monitoring of phosphorylated peptides by radioactive assay and matrix-assisted laser desorption-ionization time-of-flight mass spectrometry.p21-Activated kinase 2 (PAK2) inhibits TGF-β signaling in Madin-Darby canine kidney (MDCK) epithelial cells by interfering with the receptor-Smad interactionInhibition of G-protein-coupled receptor kinase 2 (GRK2) triggers the growth-promoting mitogen-activated protein kinase (MAPK) pathway.The Dual Role of TGFβ in Human Cancer: From Tumor Suppression to Cancer MetastasisDevelopmental and tumoral vascularization is regulated by G protein-coupled receptor kinase 2HS-173, a novel PI3K inhibitor suppresses EMT and metastasis in pancreatic cancer.The complex G protein-coupled receptor kinase 2 (GRK2) interactome unveils new physiopathological targetsRole of Smads in TGFβ signaling.The connection between GRKs and various signaling pathways involved in diabetic nephropathy.Differential Regulation of TGF-β/Smad Signaling in Hepatic Stellate Cells between Acute and Chronic Liver Injuries.Post-translational regulation of TGF-β receptor and Smad signaling.Link between cancer and Alzheimer disease via oxidative stress induced by nitric oxide-dependent mitochondrial DNA overproliferation and deletionLinker phosphorylation of Smad3 promotes fibro-carcinogenesis in chronic viral hepatitis of hepatocellular carcinoma.Multiple functions of G protein-coupled receptor kinasesRole of G protein-coupled receptor kinase 2 in tumoral angiogenesis.EIF3D promotes gallbladder cancer development by stabilizing GRK2 kinase and activating PI3K-AKT signaling pathwayGrowth inhibition of human hepatocellular carcinoma cells by overexpression of G-protein-coupled receptor kinase 2.Growth differentiation factor 15 deficiency protects against atherosclerosis by attenuating CCR2-mediated macrophage chemotaxisNegative regulation of VEGF signaling in human coronary artery endothelial cells by G protein-coupled receptor kinase 5The Role of G Protein-coupled Receptor Kinases in Cancer.Role of amino acid residues surrounding the phosphorylation site in peptide substrates of G protein-coupled receptor kinase 2 (GRK2).Peptide substrates for G protein-coupled receptor kinase 2.
P2860
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P2860
The G protein-coupled receptor kinase-2 is a TGFbeta-inducible antagonist of TGFbeta signal transduction.
description
2005 nî lūn-bûn
@nan
2005 թուականի Օգոստոսին հրատարակուած գիտական յօդուած
@hyw
2005 թվականի օգոստոսին հրատարակված գիտական հոդված
@hy
2005年の論文
@ja
2005年論文
@yue
2005年論文
@zh-hant
2005年論文
@zh-hk
2005年論文
@zh-mo
2005年論文
@zh-tw
2005年论文
@wuu
name
The G protein-coupled receptor ...... f TGFbeta signal transduction.
@ast
The G protein-coupled receptor ...... f TGFbeta signal transduction.
@en
The G protein-coupled receptor ...... f TGFbeta signal transduction.
@nl
type
label
The G protein-coupled receptor ...... f TGFbeta signal transduction.
@ast
The G protein-coupled receptor ...... f TGFbeta signal transduction.
@en
The G protein-coupled receptor ...... f TGFbeta signal transduction.
@nl
prefLabel
The G protein-coupled receptor ...... f TGFbeta signal transduction.
@ast
The G protein-coupled receptor ...... f TGFbeta signal transduction.
@en
The G protein-coupled receptor ...... f TGFbeta signal transduction.
@nl
P2093
P2860
P356
P1433
P1476
The G protein-coupled receptor ...... f TGFbeta signal transduction.
@en
P2093
Barry I Posner
Eftihia Cocolakis
Jean-Jacques Lebrun
Stéphane A Laporte
Victor M Dumas
P2860
P304
P356
10.1038/SJ.EMBOJ.7600794
P407
P577
2005-08-25T00:00:00Z