Primary cilium-dependent mechanosensing is mediated by adenylyl cyclase 6 and cyclic AMP in bone cells. - Wikidata - awgldk - TriplyDB

Primary cilium-dependent mechanosensing is mediated by adenylyl cyclase 6 and cyclic AMP in bone cells.

Primary cilium-dependent mechanosensing is mediated by adenylyl cyclase 6 and cyclic AMP in bone cells.

http://www.wikidata.org/entity/Q34017092

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Axonemal positioning and orientation in three-dimensional space for primary cilia: what is known, what is assumed, and what needs clarification The interaction of biological factors with mechanical signals in bone adaptation: recent developments Type 3 adenylyl cyclase: a key enzyme mediating the cAMP signaling in neuronal cilia Physiological mechanisms and therapeutic potential of bone mechanosensing.Mechanosensing by the primary cilium: deletion of Kif3A reduces bone formation due to loading Primary cilia-mediated mechanotransduction in human mesenchymal stem cells.Primary cilia respond to fluid shear stress and mediate flow-induced calcium deposition in osteoblasts.Microgravity induces inhibition of osteoblastic differentiation and mineralization through abrogating primary cilia.Skeletal adaptation to intramedullary pressure-induced interstitial fluid flow is enhanced in mice subjected to targeted osteocyte ablation.Enhancement of Flow-Induced AP-1 Gene Expression by Cyclosporin A Requires NFAT-Independent Signaling in Bone Cells.Systems-based identification of temporal processing pathways during bone cell mechanotransduction.Function and regulation of primary cilia and intraflagellar transport proteins in the skeleton Compressive stress induces dephosphorylation of the myosin regulatory light chain via RhoA phosphorylation by the adenylyl cyclase/protein kinase A signaling pathway.Proteomics of Primary Cilia by Proximity Labeling Osteocyte signaling in bone Mechanical regulation of signaling pathways in bone.An intelligent nano-antenna: Primary cilium harnesses TRP channels to decode polymodal stimuli The primary cilium is a self-adaptable, integrating nexus for mechanical stimuli and cellular signaling.A novel biosensor to study cAMP dynamics in cilia and flagella An Integrative Review of Mechanotransduction in Endothelial, Epithelial (Renal) and Dendritic Cells (Osteocytes).The osteocyte: an endocrine cell ... and more.Adenylyl cyclase 3 haploinsufficiency confers susceptibility to diet-induced obesity and insulin resistance in mice.The molecular basis of bone mechanotransduction.Adenylyl cyclase 6 mediates loading-induced bone adaptation in vivo.The primary cilium in different tissues-lessons from patients and animal models.The mechanics of the primary cilium: an intricate structure with complex function The primary cilium as a novel extracellular sensor in bone The extracellular matrix and ciliary signaling Emerging role of primary cilia as mechanosensors in osteocytes Non-motile primary cilia as fluid shear stress mechanosensors.Mechanically induced osteogenic lineage commitment of stem cells.A role for the primary cilium in paracrine signaling between mechanically stimulated osteocytes and mesenchymal stem cells.The primary cilium as sensor of fluid flow: new building blocks to the model. A review in the theme: cell signaling: proteins, pathways and mechanisms.Key Developments that Impacted the Field of Mechanobiology and Mechanotransduction.Fluid shear stress induces upregulation of COX-2 and PGI2 release in endothelial cells via a pathway involving PECAM-1, PI3K, FAK, and p38.Primary Cilia and Intraflagellar Transport Proteins in Bone and Cartilage.Role of the Parathyroid Hormone Type 1 Receptor (PTH1R) as a Mechanosensor in Osteocyte Survival.Bone cell mechanosensation of fluid flow stimulation: a fluid-structure interaction model characterising the role integrin attachments and primary cilia.Oscillatory fluid flow influences primary cilia and microtubule mechanics.UTP-induced ATP release is a fine-tuned signalling pathway in osteocytes.

P2860

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P2860

Primary cilium-dependent mechanosensing is mediated by adenylyl cyclase 6 and cyclic AMP in bone cells.

http://www.wikidata.org/entity/Q34017092

description

2010 nî lūn-bûn

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2010 թուականի Ապրիլին հրատարակուած գիտական յօդուած

@hyw

2010 թվականի ապրիլին հրատարակված գիտական հոդված

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2010年の論文

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2010年論文

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2010年論文

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2010年論文

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2010年論文

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2010年論文

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2010年论文

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name

Primary cilium-dependent mecha ...... and cyclic AMP in bone cells.

@ast

Primary cilium-dependent mecha ...... and cyclic AMP in bone cells.

@en

Primary cilium-dependent mecha ...... and cyclic AMP in bone cells.

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type

label

Primary cilium-dependent mecha ...... and cyclic AMP in bone cells.

@ast

Primary cilium-dependent mecha ...... and cyclic AMP in bone cells.

@en

Primary cilium-dependent mecha ...... and cyclic AMP in bone cells.

@nl

prefLabel

Primary cilium-dependent mecha ...... and cyclic AMP in bone cells.

@ast

Primary cilium-dependent mecha ...... and cyclic AMP in bone cells.

@en

Primary cilium-dependent mecha ...... and cyclic AMP in bone cells.

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Primary cilium-dependent mecha ...... and cyclic AMP in bone cells.

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Christopher R Jacobs

http://www.w3.org/2001/XMLSchema#string

Clarence C Quah

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Padmaja Tummala

http://www.w3.org/2001/XMLSchema#string

Ronald Y Kwon

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Sara Temiyasathit

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P2860

De novo formation of left-right asymmetry by posterior tilt of nodal cilia

The intraflagellar transport protein IFT20 is associated with the Golgi complex and is required for cilia assembly

Gapped BLAST and PSI-BLAST: a new generation of protein database search programs

Cloning and expression of a Ca(2+)-inhibitable adenylyl cyclase from NCB-20 cells

Polaris, a protein involved in left-right axis patterning, localizes to basal bodies and cilia

Chlamydomonas kinesin-II-dependent intraflagellar transport (IFT): IFT particles contain proteins required for ciliary assembly in Caenorhabditis elegans sensory neurons

Polycystins 1 and 2 mediate mechanosensation in the primary cilium of kidney cells

Cholangiocyte primary cilia are chemosensory organelles that detect biliary nucleotides via P2Y12 purinergic receptors

Cholangiocyte cilia detect changes in luminal fluid flow and transmit them into intracellular Ca2+ and cAMP signaling

Loss of the Tg737 protein results in skeletal patterning defects

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10.1096/FJ.09-148007

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24

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20371630

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mechanosensation

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2909282

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