Cholangiocyte cilia detect changes in luminal fluid flow and transmit them into intracellular Ca2+ and cAMP signaling
about
A method for measuring electrical signals in a primary ciliumLiver and kidney disease in ciliopathiesAutosomal dominant polycystic kidney disease: the last 3 yearsMicroRNAs in the Cholangiopathies: Pathogenesis, Diagnosis, and TreatmentPolycystic liver diseases: advanced insights into the molecular mechanismsPhysiology of cholangiocytesThe emerging role of Arf/Arl small GTPases in cilia and ciliopathies.Mechanosensing by the primary cilium: deletion of Kif3A reduces bone formation due to loadingDifferentially expressed adenylyl cyclase isoforms mediate secretory functions in cholangiocyte subpopulation.Hepatic cystogenesis is associated with abnormal expression and location of ion transporters and water channels in an animal model of autosomal recessive polycystic kidney diseaseCholangiocyte primary cilia are chemosensory organelles that detect biliary nucleotides via P2Y12 purinergic receptorsPolycystin-2 and phosphodiesterase 4C are components of a ciliary A-kinase anchoring protein complex that is disrupted in cystic kidney diseasesPrimary cilia mediate mechanosensing in bone cells by a calcium-independent mechanism.Cholangiocyte cilia are abnormal in syndromic and non-syndromic biliary atresia.Primary cilia-mediated mechanotransduction in human mesenchymal stem cells.Cilioplasm is a cellular compartment for calcium signaling in response to mechanical and chemical stimuli.Real-time vascular mechanosensation through ex vivo artery perfusion.Sensing a sensor: identifying the mechanosensory function of primary ciliaStructural and functional analyses of liver cysts from the BALB/c-cpk mouse model of polycystic kidney diseaseEstrogens and the pathophysiology of the biliary treePrimary Cilia in Tumor Biology: The Primary Cilium as a Therapeutic Target in Cholangiocarcinoma.Polycystic liver diseases.Primary cilium-dependent mechanosensing is mediated by adenylyl cyclase 6 and cyclic AMP in bone cells.Treatment strategies and clinical trial design in ADPKDHDAC6 inhibition restores ciliary expression and decreases tumor growthMammalian target of rapamycin regulates vascular endothelial growth factor-dependent liver cyst growth in polycystin-2-defective mice.Biliary exosomes influence cholangiocyte regulatory mechanisms and proliferation through interaction with primary cilia.Primary cilia mediate mechanotransduction through control of ATP-induced Ca2+ signaling in compressed chondrocytes.Direct demonstration of tubular fluid flow sensing by macula densa cells.ERK1/2-dependent vascular endothelial growth factor signaling sustains cyst growth in polycystin-2 defective mice.Hypertension in Autosomal Dominant Polycystic Kidney Disease: A Clinical and Basic Science PerspectiveThe cAMP effectors Epac and protein kinase a (PKA) are involved in the hepatic cystogenesis of an animal model of autosomal recessive polycystic kidney disease (ARPKD).Functional anatomy of normal bile ducts.Patients, cells, and organelles: the intersection of science and serendipity.The role of cilia in the regulation of bile flow.Congenital hepatic fibrosis in autosomal recessive polycystic kidney disease.Polycystic diseases in visceral organs.Protein composition and movements of membrane swellings associated with primary cilia.Force-response considerations in ciliary mechanosensation.Identification of drugs that restore primary cilium expression in cancer cells.
P2860
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P2860
Cholangiocyte cilia detect changes in luminal fluid flow and transmit them into intracellular Ca2+ and cAMP signaling
description
2006 թուականի Սեպտեմբերին հրատարակուած գիտական յօդուած
@hyw
2006 թվականի սեպտեմբերին հրատարակված գիտական հոդված
@hy
artículu científicu espublizáu en 2006
@ast
im September 2006 veröffentlichter wissenschaftlicher Artikel
@de
scientific journal article
@en
vedecký článok (publikovaný 2006/09/01)
@sk
vědecký článek publikovaný v roce 2006
@cs
wetenschappelijk artikel (gepubliceerd op 2006/09/01)
@nl
наукова стаття, опублікована у вересні 2006
@uk
مقالة علمية (نشرت في سبتمبر 2006)
@ar
name
Cholangiocyte cilia detect cha ...... llular Ca2+ and cAMP signaling
@ast
Cholangiocyte cilia detect cha ...... llular Ca2+ and cAMP signaling
@en
Cholangiocyte cilia detect cha ...... llular Ca2+ and cAMP signaling
@nl
type
label
Cholangiocyte cilia detect cha ...... llular Ca2+ and cAMP signaling
@ast
Cholangiocyte cilia detect cha ...... llular Ca2+ and cAMP signaling
@en
Cholangiocyte cilia detect cha ...... llular Ca2+ and cAMP signaling
@nl
prefLabel
Cholangiocyte cilia detect cha ...... llular Ca2+ and cAMP signaling
@ast
Cholangiocyte cilia detect cha ...... llular Ca2+ and cAMP signaling
@en
Cholangiocyte cilia detect cha ...... llular Ca2+ and cAMP signaling
@nl
P2093
P2860
P3181
P1433
P1476
Cholangiocyte cilia detect cha ...... llular Ca2+ and cAMP signaling
@en
P2093
Anatoliy I. Masyuk
Angela J. Stroope
Bing Q. Huang
Nicholas F. LaRusso
Patrick L. Splinter
Tatyana V. Masyuk
P2860
P304
P3181
P356
10.1053/J.GASTRO.2006.07.003
P407
P577
2006-09-01T00:00:00Z