Mechanism of charybdotoxin block of a voltage-gated K+ channel.
about
Ito channels are octomeric complexes with four subunits of each Kv4.2 and K+ channel-interacting protein 2Scorpion toxin block of the early K+ current (IKf) in rat dorsal root ganglion neuronesElectrostatic binding of proteins to membranes. Theoretical predictions and experimental results with charybdotoxin and phospholipid vesiclesElectrostatic interaction between charybdotoxin and a tetrameric mutant of Shaker K(+) channels.Mechanisms of maurotoxin action on Shaker potassium channels.Chemical synthesis and 1H-NMR 3D structure determination of AgTx2-MTX chimera, a new potential blocker for Kv1.2 channel, derived from MTX and AgTx2 scorpion toxinsA designer ligand specific for Kv1.3 channels from a scorpion neurotoxin-based libraryStructure of a pore-blocking toxin in complex with a eukaryotic voltage-dependent K + channelModeling the structure of agitoxin in complex with the Shaker K+ channel: a computational approach based on experimental distance restraints extracted from thermodynamic mutant cyclesIndividual IKs channels at the surface of mammalian cells contain two KCNE1 accessory subunits.Multiple binding sites for melatonin on Kv1.3Structure of conkunitzin-S1, a neurotoxin and Kunitz-fold disulfide variant from cone snailAn electrostatic interaction between TEA and an introduced pore aromatic drives spring-in-the-door inactivation in Shaker potassium channels.Mapping the functional anatomy of BgK on Kv1.1, Kv1.2, and Kv1.3. Clues to design analogs with enhanced selectivity.Fundamental aspects of protein-protein association kineticsEffect of maurotoxin, a four disulfide-bridged toxin from the chactoid scorpion Scorpio maurus, on Shaker K+ channels.Functional site of bukatoxin, an alpha-type sodium channel neurotoxin from the Chinese scorpion (Buthus martensi Karsch) venom: probable role of the (52)PDKVP(56) loop.The saxitoxin/tetrodotoxin binding site on cloned rat brain IIa Na channels is in the transmembrane electric field.Use dependence of tetrodotoxin block of sodium channels: a revival of the trapped-ion mechanism.Mapping the receptor site for ergtoxin, a specific blocker of ERG channels.Structure of the BgK-Kv1.1 complex based on distance restraints identified by double mutant cycles. Molecular basis for convergent evolution of Kv1 channel blockers.Tonic and phasic tetrodotoxin block of sodium channels with point mutations in the outer pore regionInhibition of single Shaker K channels by kappa-conotoxin-PVIIABeKm-1 is a HERG-specific toxin that shares the structure with ChTx but the mechanism of action with ErgTx1Electrostatic mechanisms underlie neomycin block of the cardiac ryanodine receptor channel (RyR2)Slow inactivation in voltage gated potassium channels is insensitive to the binding of pore occluding peptide toxins.Use of Saccharomyces cerevisiae for patch-clamp analysis of heterologous membrane proteins: characterization of Kat1, an inward-rectifying K+ channel from Arabidopsis thaliana, and comparison with endogeneous yeast channels and carriers.Functional unit size of the charybdotoxin receptor in smooth muscle.Electrostatic distance geometry in a K+ channel vestibule.Mechanism of block of the hERG K+ channel by the scorpion toxin CnErg1Permeation and block of the Kv1.2 channel examined using brownian and molecular dynamics.Modeling the binding of three toxins to the voltage-gated potassium channel (Kv1.3)The S631A mutation causes a mechanistic switch in the block of hERG channels by CnErg1.Serial perturbation of MinK in IKs implies an alpha-helical transmembrane span traversing the channel corpus.Vm24, a natural immunosuppressive peptide, potently and selectively blocks Kv1.3 potassium channels of human T cells.Designer and natural peptide toxin blockers of the KcsA potassium channel identified by phage displayProton probing of the charybdotoxin binding site of Shaker K+ channels.Inhibition of the collapse of the Shaker K+ conductance by specific scorpion toxins.Single streptomyces lividans K(+) channels: functional asymmetries and sidedness of proton activationKcsA: it's a potassium channel
P2860
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P2860
Mechanism of charybdotoxin block of a voltage-gated K+ channel.
description
1993 nî lūn-bûn
@nan
1993 թուականի Հոկտեմբերին հրատարակուած գիտական յօդուած
@hyw
1993 թվականի հոտեմբերին հրատարակված գիտական հոդված
@hy
1993年の論文
@ja
1993年論文
@yue
1993年論文
@zh-hant
1993年論文
@zh-hk
1993年論文
@zh-mo
1993年論文
@zh-tw
1993年论文
@wuu
name
Mechanism of charybdotoxin block of a voltage-gated K+ channel.
@ast
Mechanism of charybdotoxin block of a voltage-gated K+ channel.
@en
Mechanism of charybdotoxin block of a voltage-gated K+ channel.
@nl
type
label
Mechanism of charybdotoxin block of a voltage-gated K+ channel.
@ast
Mechanism of charybdotoxin block of a voltage-gated K+ channel.
@en
Mechanism of charybdotoxin block of a voltage-gated K+ channel.
@nl
prefLabel
Mechanism of charybdotoxin block of a voltage-gated K+ channel.
@ast
Mechanism of charybdotoxin block of a voltage-gated K+ channel.
@en
Mechanism of charybdotoxin block of a voltage-gated K+ channel.
@nl
P2860
P1433
P1476
Mechanism of charybdotoxin block of a voltage-gated K+ channel
@en
P2093
P2860
P304
P356
10.1016/S0006-3495(93)81200-1
P407
P577
1993-10-01T00:00:00Z