Sirt3 protects in vitro-fertilized mouse preimplantation embryos against oxidative stress-induced p53-mediated developmental arrest. - Wikidata - awgldk - TriplyDB

Sirt3 protects in vitro-fertilized mouse preimplantation embryos against oxidative stress-induced p53-mediated developmental arrest.

Sirt3 protects in vitro-fertilized mouse preimplantation embryos against oxidative stress-induced p53-mediated developmental arrest.

http://www.wikidata.org/entity/Q34028698

about

Metaboloepigenetic Regulation of Pluripotent Stem Cells In vitro fertilization (IVF) in mammals: epigenetic and developmental alterations. Scientific and bioethical implications for IVF in humans The Role of Mitochondrial DNA in Mediating Alveolar Epithelial Cell Apoptosis and Pulmonary Fibrosis Sirtuin 1 and sirtuin 3: physiological modulators of metabolism Germline energetics, aging, and female infertility Sirtuin Functions in Female Fertility: Possible Role in Oxidative Stress and Aging Function of the SIRT3 mitochondrial deacetylase in cellular physiology, cancer, and neurodegenerative disease The effects of oxidative stress on female reproduction: a review Sirt2 functions in spindle organization and chromosome alignment in mouse oocyte meiosis Maternal obesity during gestation impairs fatty acid oxidation and mitochondrial SIRT3 expression in rat offspring at weaning TEAD4 establishes the energy homeostasis essential for blastocoel formation.Mitochondrial acetylation and diseases of aging.SIRT3 opposes reprogramming of cancer cell metabolism through HIF1α destabilization A novel regulatory circuit in base excision repair involving AP endonuclease 1, Creb1 and DNA polymerase beta.Mammalian sirtuins and energy metabolism Prevention of maternal aging-associated oocyte aneuploidy and meiotic spindle defects in mice by dietary and genetic strategies.Targeting HDACs: a promising therapy for Alzheimer's disease.Sirtuin-3 (SIRT3) Protein Attenuates Doxorubicin-induced Oxidative Stress and Improves Mitochondrial Respiration in H9c2 Cardiomyocytes.Nicotinamide impairs entry into and exit from meiosis I in mouse oocytes.Different chromatin and energy/redox responses of mouse morulae and blastocysts to slow freezing and vitrification.The role of sirtuins in modulating redox stressors Sirtuin Inhibition Adversely Affects Porcine Oocyte Meiosis.Overexpression of Sirt3 inhibits lipid accumulation in macrophages through mitochondrial IDH2 deacetylation.CFTR mediates bicarbonate-dependent activation of miR-125b in preimplantation embryo development.Sirtuins Function as the Modulators in Aging-related Diseases in Common or Respectively Sirt3 prevents maternal obesity-associated oxidative stress and meiotic defects in mouse oocytes.Mild endothelial dysfunction in Sirt3 knockout mice fed a high-cholesterol diet: protective role of a novel C/EBP-β-dependent feedback regulation of SOD2 Vitrification preserves chromatin integrity, bioenergy potential and oxidative parameters in mouse embryos SIRT1, 2, 3 protect mouse oocytes from postovulatory aging.SIRT3: as simple as it seems?Deletion of Sirt3 does not affect atherosclerosis but accelerates weight gain and impairs rapid metabolic adaptation in LDL receptor knockout mice: implications for cardiovascular risk factor development.Bioenergetic and autophagic control by Sirt3 in response to nutrient deprivation in mouse embryonic fibroblasts.Nicotinamide: a class III HDACi delays in vitro aging of mouse oocytes.The SirT3 divining rod points to oxidative stress.Melatonin protects against maternal obesity-associated oxidative stress and meiotic defects in oocytes via the SIRT3-SOD2-dependent pathway.SIRT3 deficiency promotes lung fibrosis by augmenting alveolar epithelial cell mitochondrial DNA damage and apoptosis.SirT3 and p53 Deacetylation in Aging and Cancer.AGEs Decreased SIRT3 Expression and SIRT3 Activation Protected AGEs-Induced EPCs' Dysfunction and Strengthened Anti-oxidant Capacity.Release of targeted p53 from the mitochondrion as an early signal during mitochondrial dysfunction.Role of Sirt3 in mitochondrial biogenesis and developmental competence of human in vitro matured oocytes.

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Sirt3 protects in vitro-fertilized mouse preimplantation embryos against oxidative stress-induced p53-mediated developmental arrest.

http://www.wikidata.org/entity/Q34028698

description

2010 nî lūn-bûn

@nan

2010 թուականի Յուլիսին հրատարակուած գիտական յօդուած

@hyw

2010 թվականի հուլիսին հրատարակված գիտական հոդված

@hy

2010年の論文

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2010年論文

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2010年論文

@zh-hant

2010年論文

@zh-hk

2010年論文

@zh-mo

2010年論文

@zh-tw

2010年论文

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name

Sirt3 protects in vitro-fertil ...... mediated developmental arrest.

@ast

Sirt3 protects in vitro-fertil ...... mediated developmental arrest.

@en

Sirt3 protects in vitro-fertil ...... mediated developmental arrest.

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type

label

Sirt3 protects in vitro-fertil ...... mediated developmental arrest.

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Sirt3 protects in vitro-fertil ...... mediated developmental arrest.

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Sirt3 protects in vitro-fertil ...... mediated developmental arrest.

@nl

prefLabel

Sirt3 protects in vitro-fertil ...... mediated developmental arrest.

@ast

Sirt3 protects in vitro-fertil ...... mediated developmental arrest.

@en

Sirt3 protects in vitro-fertil ...... mediated developmental arrest.

@nl

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Journal of Clinical Investigation

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Sirt3 protects in vitro-fertil ...... mediated developmental arrest.

@en

P2093

Hiroki Kurihara

http://www.w3.org/2001/XMLSchema#string

Kazuo Tonami

http://www.w3.org/2001/XMLSchema#string

Koichi Nishiyama

http://www.w3.org/2001/XMLSchema#string

Nanao Horike

http://www.w3.org/2001/XMLSchema#string

Tomoichiro Asano

http://www.w3.org/2001/XMLSchema#string

Tomokazu Amano

http://www.w3.org/2001/XMLSchema#string

Yasunobu Uchijima

http://www.w3.org/2001/XMLSchema#string

Yukiko Kurihara

http://www.w3.org/2001/XMLSchema#string

Yumiko Kawamura

http://www.w3.org/2001/XMLSchema#string

P2860

Negative control of p53 by Sir2alpha promotes cell survival under stress

hSIR2(SIRT1) functions as an NAD-dependent p53 deacetylase

Reversible lysine acetylation controls the activity of the mitochondrial enzyme acetyl-CoA synthetase 2

Monoubiquitylation promotes mitochondrial p53 translocation

SIRT3, a human SIR2 homologue, is an NAD-dependent deacetylase localized to mitochondria

Sirtuins deacetylate and activate mammalian acetyl-CoA synthetases

SIRT3 is a stress-responsive deacetylase in cardiomyocytes that protects cells from stress-mediated cell death by deacetylation of Ku70

SirT3 is a nuclear NAD+-dependent histone deacetylase that translocates to the mitochondria upon cellular stress

The human silent information regulator (Sir)2 homologue hSIRT3 is a mitochondrial nicotinamide adenine dinucleotide-dependent deacetylase

Transcriptional silencing and longevity protein Sir2 is an NAD-dependent histone deacetylase

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2817-2828

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10.1172/JCI42020

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8

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120

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2010-07-19T00:00:00Z

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45275408

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20644252

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2912189

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