SIRT3 opposes reprogramming of cancer cell metabolism through HIF1α destabilization
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Prolyl hydroxylase 2 dependent and Von-Hippel-Lindau independent degradation of Hypoxia-inducible factor 1 and 2 alpha by selenium in clear cell renal cell carcinoma leads to tumor growth inhibitionAcetylation-dependent regulation of Skp2 functionSIRT2 regulates tumour hypoxia response by promoting HIF-1α hydroxylationSIRT2 maintains genome integrity and suppresses tumorigenesis through regulating APC/C activitySIRT5-mediated lysine desuccinylation impacts diverse metabolic pathwaysSIRT3 deacetylates and activates OPA1 to regulate mitochondrial dynamics during stressEAF2 suppresses hypoxia-induced factor 1α transcriptional activity by disrupting its interaction with coactivator CBP/p300Myeloid translocation gene-16 co-repressor promotes degradation of hypoxia-inducible factor 1Ascites modulates cancer cell behavior, contributing to tumor heterogeneity in ovarian cancerMitophagy plays a central role in mitochondrial ageingMitochondrial Redox Signaling and Tumor ProgressionThe Interplay of Reactive Oxygen Species, Hypoxia, Inflammation, and Sirtuins in Cancer Initiation and ProgressionDysregulated metabolism contributes to oncogenesisSirtuin 1 and sirtuin 3: physiological modulators of metabolismRole of sirtuins in ischemia-reperfusion injurySirtuins as regulators of metabolism and healthspanSIRT3 regulates progression and development of diseases of aging.Application of metabolomics in drug resistant breast cancer researchInterplay between sirtuins, MYC and hypoxia-inducible factor in cancer-associated metabolic reprogrammingTranscriptional integration of mitochondrial biogenesisSirtuins in Cancer: a Balancing Act between Genome Stability and MetabolismSirtuins, metabolism, and DNA repairFrom sirtuin biology to human diseases: an updateNonenzymatic protein acylation as a carbon stress regulated by sirtuin deacylasesHIF1α and HIF2α: sibling rivalry in hypoxic tumour growth and progressionSIRT3 inhibits prostate cancer by destabilizing oncoprotein c-MYC through regulation of the PI3K/Akt pathway.Function of the SIRT3 mitochondrial deacetylase in cellular physiology, cancer, and neurodegenerative diseaseSirtuins in metabolism, DNA repair and cancerDefining the orphan functions of lysine acetyltransferasesSirtuin deacylases: a molecular link between metabolism and immunityDeclining NAD(+) induces a pseudohypoxic state disrupting nuclear-mitochondrial communication during agingOxidative stress and ROS metabolism via down-regulation of sirtuin 3 expression in Cmah-null mice affect hearing lossSIRT3 and cancer: tumor promoter or suppressor?Low-dose radiation-induced enhancement of thymic lymphomagenesis in Lck-Bax mice is dependent on LET and genderMetformin reduces hepatic expression of SIRT3, the mitochondrial deacetylase controlling energy metabolismThe mTORC1 pathway stimulates glutamine metabolism and cell proliferation by repressing SIRT4Clonal Evolutionary Analysis during HER2 Blockade in HER2-Positive Inflammatory Breast Cancer: A Phase II Open-Label Clinical Trial of Afatinib +/- VinorelbineSIRT4 has tumor-suppressive activity and regulates the cellular metabolic response to DNA damage by inhibiting mitochondrial glutamine metabolismRole of mitochondrial dysfunction in cancer progressionROS function in redox signaling and oxidative stress
P2860
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P2860
SIRT3 opposes reprogramming of cancer cell metabolism through HIF1α destabilization
description
2011 nî lūn-bûn
@nan
2011 թուականի Մարտին հրատարակուած գիտական յօդուած
@hyw
2011 թվականի մարտին հրատարակված գիտական հոդված
@hy
2011年の論文
@ja
2011年論文
@yue
2011年論文
@zh-hant
2011年論文
@zh-hk
2011年論文
@zh-mo
2011年論文
@zh-tw
2011年论文
@wuu
name
SIRT3 opposes reprogramming of cancer cell metabolism through HIF1α destabilization
@ast
SIRT3 opposes reprogramming of cancer cell metabolism through HIF1α destabilization
@en
SIRT3 opposes reprogramming of cancer cell metabolism through HIF1α destabilization
@nl
type
label
SIRT3 opposes reprogramming of cancer cell metabolism through HIF1α destabilization
@ast
SIRT3 opposes reprogramming of cancer cell metabolism through HIF1α destabilization
@en
SIRT3 opposes reprogramming of cancer cell metabolism through HIF1α destabilization
@nl
prefLabel
SIRT3 opposes reprogramming of cancer cell metabolism through HIF1α destabilization
@ast
SIRT3 opposes reprogramming of cancer cell metabolism through HIF1α destabilization
@en
SIRT3 opposes reprogramming of cancer cell metabolism through HIF1α destabilization
@nl
P2093
P2860
P50
P1433
P1476
SIRT3 opposes reprogramming of cancer cell metabolism through HIF1α destabilization
@en
P2093
Ainara Egia
Amanda Souza
Arkaitz Carracedo
Jiangwen Zhang
Julie Teruya-Feldstein
Lydia W S Finley
Marcia C Haigis
P2860
P304
P356
10.1016/J.CCR.2011.02.014
P577
2011-03-01T00:00:00Z