Assessment of the pharmacology and tolerability of PF-04457845, an irreversible inhibitor of fatty acid amide hydrolase-1, in healthy subjects.
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Chemical probes of endocannabinoid metabolismFAAH inhibitors in the limelight, but regrettablyPreclinical Characterization of the FAAH Inhibitor JNJ-42165279Latest advances in the discovery of fatty acid amide hydrolase inhibitorsExploiting modern cannabinoid pharmacology for therapeutic gain?Interactions of Cannabinoids With Biochemical SubstratesPET imaging of fatty acid amide hydrolase with [(18)F]DOPP in nonhuman primates.Spinal cannabinoid receptor type 2 agonist reduces mechanical allodynia and induces mitogen-activated protein kinase phosphatases in a rat model of neuropathic painBlocking of fatty acid amide hydrolase activity with PF-04457845 in human brain: a positron emission tomography study with the novel radioligand [(11)C]CURB.Programming of neural cells by (endo)cannabinoids: from physiological rules to emerging therapies.The synthesis and in vivo evaluation of [18F]PF-9811: a novel PET ligand for imaging brain fatty acid amide hydrolase (FAAH).Synthesis and Preliminary PET Imaging Studies of a FAAH Radiotracer ([¹¹C]MPPO) Based on α-Ketoheterocyclic Scaffold.Modulating the endocannabinoid system in human health and disease--successes and failuresScreening Medications for the Treatment of Cannabis Use Disorder.Translational PK-PD modeling in pain.Involvement of the endocannabinoid system in osteoarthritis pain.Preclinical Studies of Cannabinoid Reward, Treatments for Cannabis Use Disorder, and Addiction-Related Effects of Cannabinoid Exposure.The cannabinoid system and pain.A systems pharmacology perspective on the clinical development of Fatty Acid amide hydrolase inhibitors for pain.Aryl Piperazinyl Ureas as Inhibitors of Fatty Acid Amide Hydrolase (FAAH) in Rat, Dog, and Primate.Interaction between the endocannabinoid and serotonergic system in the exhibition of head twitch response in four mouse strains.Opioid withdrawal suppression efficacy of oral dronabinol in opioid dependent humans.Safety, Tolerability and Pharmacokinetics of FAAH Inhibitor V158866: A Double-Blind, Randomised, Placebo-Controlled Phase I Study in Healthy VolunteersSynthesis and preclinical evaluation of [11C-carbonyl]PF-04457845 for neuroimaging of fatty acid amide hydrolase.Fatty Acid Amide Hydrolase Binding in Brain of Cannabis Users: Imaging With the Novel Radiotracer [11C]CURB.The endocannabinoid system in cardiovascular function: novel insights and clinical implications.Activity-based protein profiling reveals off-target proteins of the FAAH inhibitor BIA 10-2474.Role of endocannabinoid signalling in the dorsolateral periaqueductal grey in the modulation of distinct panic-like responses.Synthesis and preclinical evaluation of [¹⁸F]FCHC for neuroimaging of fatty acid amide hydrolase.The MOBILE Study-A Phase IIa Enriched Enrollment Randomized Withdrawal Trial to Assess the Analgesic Efficacy and Safety of ASP8477, a Fatty Acid Amide Hydrolase Inhibitor, in Patients with Peripheral Neuropathic Pain.A robust capillary liquid chromatography/tandem mass spectrometry method for quantitation of neuromodulatory endocannabinoids.Fatty Acid Amide Hydrolase Inhibition by JNJ-42165279: A Multiple-Ascending Dose and a Positron Emission Tomography Study in Healthy Volunteers.Potential of Endocannabinoids to Control Bladder Pain.Design and Potency of Dual Soluble Epoxide Hydrolase/Fatty Acid Amide Hydrolase Inhibitors
P2860
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P2860
Assessment of the pharmacology and tolerability of PF-04457845, an irreversible inhibitor of fatty acid amide hydrolase-1, in healthy subjects.
description
2012 nî lūn-bûn
@nan
2012 թուականի Մայիսին հրատարակուած գիտական յօդուած
@hyw
2012 թվականի մայիսին հրատարակված գիտական հոդված
@hy
2012年の論文
@ja
2012年論文
@yue
2012年論文
@zh-hant
2012年論文
@zh-hk
2012年論文
@zh-mo
2012年論文
@zh-tw
2012年论文
@wuu
name
Assessment of the pharmacology ...... rolase-1, in healthy subjects.
@ast
Assessment of the pharmacology ...... rolase-1, in healthy subjects.
@en
Assessment of the pharmacology ...... rolase-1, in healthy subjects.
@nl
type
label
Assessment of the pharmacology ...... rolase-1, in healthy subjects.
@ast
Assessment of the pharmacology ...... rolase-1, in healthy subjects.
@en
Assessment of the pharmacology ...... rolase-1, in healthy subjects.
@nl
prefLabel
Assessment of the pharmacology ...... rolase-1, in healthy subjects.
@ast
Assessment of the pharmacology ...... rolase-1, in healthy subjects.
@en
Assessment of the pharmacology ...... rolase-1, in healthy subjects.
@nl
P2093
P2860
P1476
Assessment of the pharmacology ...... rolase-1, in healthy subjects.
@en
P2093
Gai Ling Li
Gary W Jay
Helen Winter
John P Huggins
Rosalin Arends
P2860
P304
P356
10.1111/J.1365-2125.2011.04137.X
P407
P577
2012-05-01T00:00:00Z