MEKK1 plays a critical role in activating the transcription factor C/EBP-beta-dependent gene expression in response to IFN-gamma. - Wikidata - awgldk - TriplyDB

MEKK1 plays a critical role in activating the transcription factor C/EBP-beta-dependent gene expression in response to IFN-gamma.

MEKK1 plays a critical role in activating the transcription factor C/EBP-beta-dependent gene expression in response to IFN-gamma.

http://www.wikidata.org/entity/Q34030536

about

Essential role for Mnk kinases in type II interferon (IFNgamma) signaling and its suppressive effects on normal hematopoiesis Cooperative NCoR/SMRT interactions establish a corepressor-based strategy for integration of inflammatory and anti-inflammatory signaling pathways High glucose-induced increased expression of endothelin-1 in human endothelial cells is mediated by activated CCAAT/enhancer-binding proteins The Med1 subunit of transcriptional mediator plays a central role in regulating CCAAT/enhancer-binding protein-beta-driven transcription in response to interferon-gamma Genome-wide association analysis of chronic lymphocytic leukaemia, Hodgkin lymphoma and multiple myeloma identifies pleiotropic risk loci Activation of TORC1 transcriptional coactivator through MEKK1-induced phosphorylation Genome-wide physical activity interactions in adiposity - A meta-analysis of 200,452 adults.Sequential phosphorylation of CCAAT enhancer-binding protein beta by MAPK and glycogen synthase kinase 3beta is required for adipogenesis Interferons, signal transduction pathways, and the central nervous system.C/EBP transcription factors regulate NADPH oxidase in human aortic smooth muscle cells.The transcription factor C/EBP-β mediates constitutive and LPS-inducible transcription of murine SerpinB2.Distinct mechanisms for induction and tolerance regulate the immediate early genes encoding interleukin 1β and tumor necrosis factor α.STAT-phosphorylation-independent induction of interferon regulatory factor-9 by interferon-beta Regulation of the death-associated protein kinase 1 expression and autophagy via ATF6 requires apoptosis signal-regulating kinase 1.LPS-Induced G-CSF Expression in Macrophages Is Mediated by ERK2, but Not ERK1 The tumor microenvironment strongly impacts master transcriptional regulators and gene expression class of glioblastoma.IFN-γ elicits macrophage autophagy via the p38 MAPK signaling pathway.Critical role for transcription factor C/EBP-beta in regulating the expression of death-associated protein kinase 1.ERK signaling regulates tumor promoter induced c-Jun recruitment at the Fra-1 promoter.The cytosolic pattern recognition receptor NOD1 induces inflammatory interleukin-8 during Chlamydia trachomatis infection.The interferon signaling network and transcription factor C/EBP-beta CCAAT/enhancer-binding protein beta and delta binding to CIITA promoters is associated with the inhibition of CIITA expression in response to Mycobacterium tuberculosis 19-kDa lipoprotein.Profiling the human protein-DNA interactome reveals ERK2 as a transcriptional repressor of interferon signaling.Interferon receptor signaling in malignancy: a network of cellular pathways defining biological outcomes.Role of STAT1, NF-kappaB, and C/EBPbeta in the macrophage transcriptional regulation of hepcidin by mycobacterial infection and IFN-gamma.Interferon-gamma suppresses S100A4 transcription independently of apoptosis or cell cycle arrest.Control of gp130 expression by the mitogen-activated protein kinase ERK2.Inducible gene deletion reveals different roles for B-Raf and Raf-1 in B-cell antigen receptor signalling.Involvement of ERK and JNK pathways in IFN-γ-induced B7-DC expression on tumor cells.A role for mixed lineage kinases in regulating transcription factor CCAAT/enhancer-binding protein-{beta}-dependent gene expression in response to interferon-{gamma}.Aeromonas hydrophila cytotoxic enterotoxin activates mitogen-activated protein kinases and induces apoptosis in murine macrophages and human intestinal epithelial cells.Interferon-gamma induces C/EBP beta expression and activity through MEK/ERK and p38 in T84 colon epithelial cells.Src mediates cytokine-stimulated gene expression in airway myocytes through ERK MAPK.IL-17 receptor signaling inhibits C/EBPbeta by sequential phosphorylation of the regulatory 2 domain.Virtual Sorting Has a Distinctive Advantage in Identification of Anticorrelated Genes and Further Negative Regulators of Immune Cell Subpopulations.Transcription factor CCAAT/enhancer-binding protein-β upregulates microRNA, let-7f-1 in human endocervical cells.Polymorphisms in key bone modulator cytokines genes influence bisphosphonates therapy in postmenopausal women.Immediate-Early Promoter-Driven Transgenic Reporter System for Neuroethological Research in a Hemimetabolous Insect

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P2860

MEKK1 plays a critical role in activating the transcription factor C/EBP-beta-dependent gene expression in response to IFN-gamma.

http://www.wikidata.org/entity/Q34030536

description

2002 nî lūn-bûn

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2002 թուականի Յունիսին հրատարակուած գիտական յօդուած

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2002 թվականի հունիսին հրատարակված գիտական հոդված

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2002年の論文

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MEKK1 plays a critical role in ...... sion in response to IFN-gamma.

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MEKK1 plays a critical role in ...... sion in response to IFN-gamma.

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MEKK1 plays a critical role in ...... sion in response to IFN-gamma.

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Proceedings of the National Academy of Sciences of the United States of America

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MEKK1 plays a critical role in ...... sion in response to IFN-gamma.

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Catrin Pritchard

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Daniel J Lindner

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Dhananjaya V Kalvakolanu

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Gilles Pagés

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Junbo Hu

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Leonidas C Platanias

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Paul S Shapiro

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Peter F Johnson

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Qingjun Meng

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Sanjit K Roy

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P2860

Signaling by proinflammatory cytokines: oligomerization of TRAF2 and TRAF6 is sufficient for JNK and IKK activation and target gene induction via an amino-terminal effector domain

Collaboration of signal transducer and activator of transcription 1 (STAT1) and BRCA1 in differential regulation of IFN-gamma target genes

MEKK1 activates both IkappaB kinase alpha and IkappaB kinase beta

How cells respond to interferons

Activation of stress-activated protein kinase by MEKK1 phosphorylation of its activator SEK1

Defective thymocyte maturation in p44 MAP kinase (Erk 1) knockout mice

Phosphorylation of rat serine 105 or mouse threonine 217 in C/EBP beta is required for hepatocyte proliferation induced by TGF alpha

MEKK1 binds raf-1 and the ERK2 cascade components

Role of MEKK1 in cell survival and activation of JNK and ERK pathways defined by targeted gene disruption

MEK kinase activity is not necessary for Raf-1 function.

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7945-7950

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scholarly article

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10.1073/PNAS.122075799

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12

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99

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Jacques Pouysségur

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2002-06-04T00:00:00Z

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11325703

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12048245

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123000

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