Phylogeny of Cas9 determines functional exchangeability of dual-RNA and Cas9 among orthologous type II CRISPR-Cas systems
about
Concerning RNA-guided gene drives for the alteration of wild populationsDiscovery and Functional Characterization of Diverse Class 2 CRISPR-Cas SystemsThe Rise of CRISPR/Cas for Genome Editing in Stem CellsGenome-editing Technologies for Gene and Cell TherapyNuclease Target Site Selection for Maximizing On-target Activity and Minimizing Off-target Effects in Genome EditingDiversity of CRISPR-Cas immune systems and molecular machinesDesigned nucleases for targeted genome editingClassification and evolution of type II CRISPR-Cas systemsBiogenesis pathways of RNA guides in archaeal and bacterial CRISPR-Cas adaptive immunityMaking designer mutants in model organismsStructures of Cas9 Endonucleases Reveal RNA-Mediated Conformational ActivationCrystal Structure of Cas9 in Complex with Guide RNA and Target DNAStructural basis of PAM-dependent target DNA recognition by the Cas9 endonucleaseThe CRISPR system can correct or modify the expression of genes responsible for hereditary diseasesDevelopment and applications of CRISPR-Cas9 for genome engineering.Exploiting the CRISPR/Cas9 PAM Constraint for Single-Nucleotide Resolution InterventionsStructure Principles of CRISPR-Cas Surveillance and Effector ComplexesCHOPCHOP v2: a web tool for the next generation of CRISPR genome engineeringImproved bi-allelic modification of a transcriptionally silent locus in patient-derived iPSC by Cas9 nickaseEngineering of temperature- and light-switchable Cas9 variantsRNA sequencing uncovers antisense RNAs and novel small RNAs in Streptococcus pyogenesHarnessing CRISPR-Cas9 immunity for genetic engineeringAnnotation and Classification of CRISPR-Cas Systems.An updated evolutionary classification of CRISPR-Cas systems.Genetic and epigenetic control of gene expression by CRISPR-Cas systems.In vivo genome editing with a small Cas9 orthologue derived from Campylobacter jejuniExploiting CRISPR-Cas to manipulate Enterococcus faecalis populations.Unravelling the structural and mechanistic basis of CRISPR-Cas systems.Cas9 specifies functional viral targets during CRISPR-Cas adaptation.Engineering synthetic TALE and CRISPR/Cas9 transcription factors for regulating gene expressionCRISPR-based technologies: prokaryotic defense weapons repurposedGUIDE-seq enables genome-wide profiling of off-target cleavage by CRISPR-Cas nucleases.Development of an intein-mediated split-Cas9 system for gene therapyEngineered CRISPR-Cas9 nucleases with altered PAM specificitiesHigh-fidelity CRISPR-Cas9 nucleases with no detectable genome-wide off-target effects.Multiplex CRISPR/Cas9-based genome engineering from a single lentiviral vector.Structure and Engineering of Francisella novicida Cas9.Applications of CRISPR technologies in research and beyond.Functional genetics for all: engineered nucleases, CRISPR and the gene editing revolutionRole of the Streptococcus mutans CRISPR-Cas systems in immunity and cell physiology.
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P2860
Phylogeny of Cas9 determines functional exchangeability of dual-RNA and Cas9 among orthologous type II CRISPR-Cas systems
description
2013 nî lūn-bûn
@nan
2013 թուականի Նոյեմբերին հրատարակուած գիտական յօդուած
@hyw
2013 թվականի նոյեմբերին հրատարակված գիտական հոդված
@hy
2013年の論文
@ja
2013年論文
@yue
2013年論文
@zh-hant
2013年論文
@zh-hk
2013年論文
@zh-mo
2013年論文
@zh-tw
2013年论文
@wuu
name
Phylogeny of Cas9 determines f ...... ous type II CRISPR-Cas systems
@ast
Phylogeny of Cas9 determines f ...... ous type II CRISPR-Cas systems
@en
Phylogeny of Cas9 determines f ...... ous type II CRISPR-Cas systems
@nl
type
label
Phylogeny of Cas9 determines f ...... ous type II CRISPR-Cas systems
@ast
Phylogeny of Cas9 determines f ...... ous type II CRISPR-Cas systems
@en
Phylogeny of Cas9 determines f ...... ous type II CRISPR-Cas systems
@nl
prefLabel
Phylogeny of Cas9 determines f ...... ous type II CRISPR-Cas systems
@ast
Phylogeny of Cas9 determines f ...... ous type II CRISPR-Cas systems
@en
Phylogeny of Cas9 determines f ...... ous type II CRISPR-Cas systems
@nl
P2860
P50
P356
P1476
Phylogeny of Cas9 determines f ...... ous type II CRISPR-Cas systems
@en
P2093
Janek Bzdrenga
P2860
P304
P356
10.1093/NAR/GKT1074
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P50
P577
2013-11-22T00:00:00Z