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Chronic treatment with novel brain-penetrating selective NOP receptor agonist MT-7716 reduces alcohol drinking and seeking in the ratNociceptin induces hypophagia in the perifornical and lateral hypothalamic area.Buprenorphine reduces alcohol drinking through activation of the nociceptin/orphanin FQ-NOP receptor systemGenetically selected Marchigian Sardinian alcohol-preferring (msP) rats: an animal model to study the neurobiology of alcoholism.The pharmacology of Ro 64-6198, a systemically active, nonpeptide NOP receptor (opiate receptor-like 1, ORL-1) agonist with diverse preclinical therapeutic activity.Nociceptin/orphanin FQ presynaptically decreases GABAergic transmission and blocks the ethanol-induced increase of GABA release in central amygdala.Dysregulation of nociceptin/orphanin FQ activity in the amygdala is linked to excessive alcohol drinking in the rat.Comparison of the ORL1 receptor-mediated inhibition of noradrenaline release in human and rat neocortical slicesNociceptin/orphanin FQ: actions within the brain.In vitro and in vivo studies on UFP-112, a novel potent and long lasting agonist selective for the nociceptin/orphanin FQ receptorThe impact of emotional stress early in life on adult voluntary ethanol intake-results of maternal separation in rats.Evaluation of the Tolerability of Switching Patients on Chronic Full μ-Opioid Agonist Therapy to Buccal BuprenorphineEvidence for association of two variants of the nociceptin/orphanin FQ receptor gene OPRL1 with vulnerability to develop opiate addiction in Caucasians.Nociceptin/orphanin FQ blockade of corticotropin-releasing factor-induced gamma-aminobutyric acid release in central amygdala is enhanced after chronic ethanol exposure.Development of pharmacotherapies for drug addiction: a Rosetta stone approach.Focus on: Neuroscience and treatment: the potential of neuroscience to inform treatment.Role of CRF and other neuropeptides in stress-induced reinstatement of drug seeking.MT-7716, a novel selective nonpeptidergic NOP receptor agonist, effectively blocks ethanol-induced increase in GABAergic transmission in the rat central amygdala.Recently patented and promising ORL-1 ligands: where have we been and where are we going?UFP-112 a potent and long-lasting agonist selective for the Nociceptin/Orphanin FQ receptor.Nociceptin/orphanin FQ decreases glutamate transmission and blocks ethanol-induced effects in the central amygdala of naive and ethanol-dependent rats.Association between the nociceptin receptor gene (OPRL1) single nucleotide polymorphisms and alcohol dependence.Genetic Deletion of the Nociceptin/Orphanin FQ Receptor in the Rat Confers Resilience to the Development of Drug Addiction.∆(9)-Tetrahydrocannabinol decreases NOP receptor density and mRNA levels in human SH-SY5Y cells.Efficacy and tolerability of buccal buprenorphine in opioid-naive patients with moderate to severe chronic low back pain.Effect of novel nociceptin/orphanin FQ-NOP receptor ligands on ethanol drinking in alcohol-preferring msP rats.Association analysis of genes encoding the nociceptin receptor (OPRL1) and its endogenous ligand (PNOC) with alcohol or illicit drug dependence.Caloric restriction increases the sensitivity to the hyperphagic effect of nociceptin/orphanin FQ limiting its ability to reduce binge eating in female rats.
P2860
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P2860
description
2000 nî lūn-bûn
@nan
2000 թուականի Յուլիսին հրատարակուած գիտական յօդուած
@hyw
2000 թվականի հուլիսին հրատարակված գիտական հոդված
@hy
2000年の論文
@ja
2000年論文
@yue
2000年論文
@zh-hant
2000年論文
@zh-hk
2000年論文
@zh-mo
2000年論文
@zh-tw
2000年论文
@wuu
name
Nociceptin/orphanin FQ and drugs of abuse.
@ast
Nociceptin/orphanin FQ and drugs of abuse.
@en
Nociceptin/orphanin FQ and drugs of abuse.
@nl
type
label
Nociceptin/orphanin FQ and drugs of abuse.
@ast
Nociceptin/orphanin FQ and drugs of abuse.
@en
Nociceptin/orphanin FQ and drugs of abuse.
@nl
prefLabel
Nociceptin/orphanin FQ and drugs of abuse.
@ast
Nociceptin/orphanin FQ and drugs of abuse.
@en
Nociceptin/orphanin FQ and drugs of abuse.
@nl
P2093
P1433
P1476
Nociceptin/orphanin FQ and drugs of abuse.
@en
P2093
R Ciccocioppo
S Angeletti
P304
P356
10.1016/S0196-9781(00)00245-X
P577
2000-07-01T00:00:00Z