Dimeric CRISPR RNA-Guided FokI-dCas9 Nucleases Directed by Truncated gRNAs for Highly Specific Genome Editing. - Wikidata - awgldk - TriplyDB

Dimeric CRISPR RNA-Guided FokI-dCas9 Nucleases Directed by Truncated gRNAs for Highly Specific Genome Editing.

Dimeric CRISPR RNA-Guided FokI-dCas9 Nucleases Directed by Truncated gRNAs for Highly Specific Genome Editing.

http://www.wikidata.org/entity/Q34044207

about

Customizing the genome as therapy for the β-hemoglobinopathies Genome Engineering with TALE and CRISPR Systems in Neuroscience CRISPR-Cas9 as a Powerful Tool for Efficient Creation of Oncolytic Viruses CRISPR/Cas9 and cancer targets: future possibilities and present challenges Advanced In vivo Use of CRISPR/Cas9 and Anti-sense DNA Inhibition for Gene Manipulation in the Brain How specific is CRISPR/Cas9 really?Off-target Effects in CRISPR/Cas9-mediated Genome Engineering High-fidelity CRISPR-Cas9 nucleases with no detectable genome-wide off-target effects.Conditional Control of CRISPR/Cas9 Function.Applications of CRISPR technologies in research and beyond.Non-Homologous End Joining and Homology Directed DNA Repair Frequency of Double-Stranded Breaks Introduced by Genome Editing Reagents.Genome Editing in Human Cells Using CRISPR/Cas Nucleases.Efficient generation of FVII gene knockout mice using CRISPR/Cas9 nuclease and truncated guided RNAs.The Amaryllidaceae alkaloids: biosynthesis and methods for enzyme discovery.Different Effects of sgRNA Length on CRISPR-mediated Gene Knockout Efficiency.Multiplex CRISPR/Cas9-based genome engineering enhanced by Drosha-mediated sgRNA-shRNA structure.TALEN/CRISPR-mediated engineering of a promoterless anti-viral RNAi hairpin into an endogenous miRNA locus.Single Cas9 nickase induced generation of NRAMP1 knockin cattle with reduced off-target effects.Developmental history and application of CRISPR in human disease.CRISPR-Cas9 for medical genetic screens: applications and future perspectives.Creating and evaluating accurate CRISPR-Cas9 scalpels for genomic surgery.Advancing chimeric antigen receptor T cell therapy with CRISPR/Cas9.Defining and improving the genome-wide specificities of CRISPR-Cas9 nucleases.The big bang of genome editing technology: development and application of the CRISPR/Cas9 system in disease animal models CRISPR-Cas9 technology: applications and human disease modelling.Methods for Optimizing CRISPR-Cas9 Genome Editing Specificity.CRISPR-Based Technologies for the Manipulation of Eukaryotic Genomes.Genome editing: a robust technology for human stem cells.Functional screening of guide RNAs targeting the regulatory and structural HIV-1 viral genome for a cure of AIDS.Deep mutational scanning of S. pyogenes Cas9 reveals important functional domains.Optimized guide RNA structure for genome editing via Cas9.CRISPR/Cas9-Advancing Orthopoxvirus Genome Editing for Vaccine and Vector Development.Break Breast Cancer Addiction by CRISPR/Cas9 Genome Editing.Crossing enhanced and high fidelity SpCas9 nucleases to optimize specificity and cleavage.Re-engineered RNA-Guided FokI-Nucleases for Improved Genome Editing in Human Cells.Precise Cas9 targeting enables genomic mutation prevention.Nuclease-Mediated Gene Therapies for Inherited Metabolic Diseases of the Liver.Applications of CRISPR/Cas9 in the Mammalian Central Nervous System.One-step genetic correction of hemoglobin E/beta-thalassemia patient-derived iPSCs by the CRISPR/Cas9 system.CRISPR/Cas9 Technology as an Emerging Tool for Targeting Amyotrophic Lateral Sclerosis (ALS).

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Dimeric CRISPR RNA-Guided FokI-dCas9 Nucleases Directed by Truncated gRNAs for Highly Specific Genome Editing.

http://www.wikidata.org/entity/Q34044207

description

2015 nî lūn-bûn

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2015 թուականի Յուլիսին հրատարակուած գիտական յօդուած

@hyw

2015 թվականի հուլիսին հրատարակված գիտական հոդված

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2015年の論文

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2015年論文

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2015年論文

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2015年論文

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2015年論文

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2015年論文

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2015年论文

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name

Dimeric CRISPR RNA-Guided FokI ...... ighly Specific Genome Editing.

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Dimeric CRISPR RNA-Guided FokI ...... ighly Specific Genome Editing.

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Dimeric CRISPR RNA-Guided FokI ...... ighly Specific Genome Editing.

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Dimeric CRISPR RNA-Guided FokI ...... ighly Specific Genome Editing.

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Dimeric CRISPR RNA-Guided FokI ...... ighly Specific Genome Editing.

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Dimeric CRISPR RNA-Guided FokI ...... ighly Specific Genome Editing.

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Dimeric CRISPR RNA-Guided FokI ...... ighly Specific Genome Editing.

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Dimeric CRISPR RNA-Guided FokI ...... ighly Specific Genome Editing.

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Dimeric CRISPR RNA-Guided FokI ...... ighly Specific Genome Editing.

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Human Gene Therapy

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Dimeric CRISPR RNA-Guided FokI ...... ighly Specific Genome Editing.

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Cyd Khayter

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J Keith Joung

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Nicolas Wyvekens

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Shengdar Q Tsai

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Ved V Topkar

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P2860

Genome engineering using the CRISPR-Cas9 system

FokI dimerization is required for DNA cleavage

A Programmable Dual-RNA-Guided DNA Endonuclease in Adaptive Bacterial Immunity

Development and applications of CRISPR-Cas9 for genome engineering.

Genome editing. The new frontier of genome engineering with CRISPR-Cas9

Fusion of catalytically inactive Cas9 to FokI nuclease improves the specificity of genome modification

Fast and accurate long-read alignment with Burrows-Wheeler transform

Integrative genomics viewer

CRISPR-Cas systems for editing, regulating and targeting genomes

CAS9 transcriptional activators for target specificity screening and paired nickases for cooperative genome engineering

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10.1089/HUM.2015.084

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7

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26

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