Conditional deletion of insulin-like growth factor-I in collagen type 1alpha2-expressing cells results in postnatal lethality and a dramatic reduction in bone accretion - Wikidata - awgldk - TriplyDB

Conditional deletion of insulin-like growth factor-I in collagen type 1alpha2-expressing cells results in postnatal lethality and a dramatic reduction in bone accretion

Conditional deletion of insulin-like growth factor-I in collagen type 1alpha2-expressing cells results in postnatal lethality and a dramatic reduction in bone accretion

http://www.wikidata.org/entity/Q34046618

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Role and Mechanisms of Actions of Thyroid Hormone on the Skeletal Development Bone cell communication factors and Semaphorins Multiple Effects of Growth Hormone in the Body: Is it Really the Hormone for Growth?The Bone Marrow-Derived Stromal Cells: Commitment and Regulation of Adipogenesis Role of IGF-I signaling in muscle bone interactions Regulation of Long Bone Growth in Vertebrates; It Is Time to Catch Up Mex3c regulates insulin-like growth factor 1 (IGF1) expression and promotes postnatal growth Targeted disruption of nuclear factor erythroid-derived 2-like 1 in osteoblasts reduces bone size and bone formation in mice.Ephrin B1 regulates bone marrow stromal cell differentiation and bone formation by influencing TAZ transactivation via complex formation with NHERF1.Minireview: mechanisms of growth hormone-mediated gene regulation.Insulin-like growth factor 1 physiology: lessons from mouse models.Does the GH/IGF-1 axis contribute to skeletal sexual dimorphism? Evidence from mouse studies.Insulin like growth factor-I: a critical mediator of the skeletal response to parathyroid hormone Direct stimulation of bone mass by increased GH signalling in the osteoblasts of Socs2-/- mice Aerobic glycolysis in osteoblasts.The role of GH/IGF-I-mediated mechanisms in sex differences in cortical bone size in mice Superoxide anion radicals induce IGF-1 resistance through concomitant activation of PTP1B and PTEN.Conditional disruption of miR17-92 cluster in collagen type I-producing osteoblasts results in reduced periosteal bone formation and bone anabolic response to exercise.Role of WNT16 in the regulation of periosteal bone formation in female mice.Insulin-like growth factor (IGF)-I and IGF-II contribute differentially to the phenotype of pregnancy associated plasma protein-A knock-out mice.IGF-1 and bone: New discoveries from mouse models Conditional disruption of IGF-I gene in type 1α collagen-expressing cells shows an essential role of IGF-I in skeletal anabolic response to loading Ascorbic acid regulates osterix expression in osteoblasts by activation of prolyl hydroxylase and ubiquitination-mediated proteosomal degradation pathway The role of IGF-1 for fracture risk in men.Genetic evidence that thyroid hormone is indispensable for prepubertal insulin-like growth factor-I expression and bone acquisition in mice.Conditional Deletion of Prolyl Hydroxylase Domain-Containing Protein 2 (Phd2) Gene Reveals Its Essential Role in Chondrocyte Function and Endochondral Bone Formation.Regulation of skeletal growth and mineral acquisition by the GH/IGF-1 axis: Lessons from mouse models.Prepubertal OVX increases IGF-I expression and bone accretion in C57BL/6J mice.The hormonal action of IGF1 in postnatal mouse growth.Differential effects of IGF-1 deficiency during the life span on structural and biomechanical properties in the tibia of aged mice.Haploinsufficiency of osterix in chondrocytes impairs skeletal growth in mice.The acid-labile subunit is required for full effects of exogenous growth hormone on growth and carbohydrate metabolism Prolyl Hydroxylase Domain-Containing Protein 2 (Phd2) Regulates Chondrocyte Differentiation and Secondary Ossification in Mice.The role of liver-derived insulin-like growth factor-I.The new frontier of bone formation: a breakthrough in postmenopausal osteoporosis?IRS-1 Functions as a Molecular Scaffold to Coordinate IGF-I/IGFBP-2 Signaling During Osteoblast Differentiation.Function of matrix IGF-1 in coupling bone resorption and formation.Role of Osteocyte-derived Insulin-Like Growth Factor I in Developmental Growth, Modeling, Remodeling, and Regeneration of the Bone.Investigational anabolic therapies for osteoporosis.Role of insulin-like growth factor-1 in the regulation of skeletal growth.

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Conditional deletion of insulin-like growth factor-I in collagen type 1alpha2-expressing cells results in postnatal lethality and a dramatic reduction in bone accretion

http://www.wikidata.org/entity/Q34046618

description

2007 nî lūn-bûn

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2007 թուականի Օգոստոսին հրատարակուած գիտական յօդուած

@hyw

2007 թվականի օգոստոսին հրատարակված գիտական հոդված

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2007年の論文

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2007年論文

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2007年論文

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2007年論文

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2007年論文

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2007年論文

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2007年论文

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Conditional deletion of insuli ...... ic reduction in bone accretion

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Conditional deletion of insuli ...... ic reduction in bone accretion

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Conditional deletion of insuli ...... ic reduction in bone accretion

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type

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Conditional deletion of insuli ...... ic reduction in bone accretion

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Conditional deletion of insuli ...... ic reduction in bone accretion

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Conditional deletion of insuli ...... ic reduction in bone accretion

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Conditional deletion of insuli ...... ic reduction in bone accretion

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Conditional deletion of insuli ...... ic reduction in bone accretion

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Conditional deletion of insuli ...... ic reduction in bone accretion

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Conditional deletion of insuli ...... ic reduction in bone accretion

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David J Baylink

http://www.w3.org/2001/XMLSchema#string

Jon E Wergedal

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Kristen E Govoni

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Lore Florin

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Peter Angel

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Subburaman Mohan

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P2860

Codon-improved Cre recombinase (iCre) expression in the mouse

Insulin-like growth factor-binding proteins in serum and other biological fluids: regulation and functions

Insulin-like growth factors and their binding proteins: biological actions

Regulation of insulin-like growth factor binding protein-5, four and a half lim-2, and a disintegrin and metalloprotease-9 expression in osteoblasts

IGF-binding proteins are multifunctional and act via IGF-dependent and -independent mechanisms

Mice carrying null mutations of the genes encoding insulin-like growth factor I (Igf-1) and type 1 IGF receptor (Igf1r)

Role of insulin-like growth factors in embryonic and postnatal growth

Disruption of insulin-like growth factor-I expression in type IIalphaI collagen-expressing cells reduces bone length and width in mice.

Insulin-like growth factor-binding protein-5 induces a gender-related decrease in bone mineral density in transgenic mice

Evidence that sensitivity to growth hormone (GH) is growth period and tissue type dependent: studies in GH-deficient lit/lit mice.

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5706-5715

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10.1210/EN.2007-0608

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148

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17717052

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