Conditional disruption of IGF-I gene in type 1α collagen-expressing cells shows an essential role of IGF-I in skeletal anabolic response to loading - Wikidata - awgldk - TriplyDB

Conditional disruption of IGF-I gene in type 1α collagen-expressing cells shows an essential role of IGF-I in skeletal anabolic response to loading

Conditional disruption of IGF-I gene in type 1α collagen-expressing cells shows an essential role of IGF-I in skeletal anabolic response to loading

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Stress and Alterations in Bones: An Interdisciplinary Perspective Does the GH/IGF-1 axis contribute to skeletal sexual dimorphism? Evidence from mouse studies.Transgenic overexpression of ephrin b1 in bone cells promotes bone formation and an anabolic response to mechanical loading in mice.Conditional disruption of miR17-92 cluster in collagen type I-producing osteoblasts results in reduced periosteal bone formation and bone anabolic response to exercise.Role of WNT16 in the regulation of periosteal bone formation in female mice.In vivo evidence of IGF-I-estrogen crosstalk in mediating the cortical bone response to mechanical strain.Mechanical load increases in bone formation via a sclerostin-independent pathway.Bone and skeletal muscle: Key players in mechanotransduction and potential overlapping mechanisms.Regulation of skeletal growth and mineral acquisition by the GH/IGF-1 axis: Lessons from mouse models.IGFBP-2 directly stimulates osteoblast differentiation.ENU mutation mapped to a distal region of chromosome 11 is a major determinant of bone size.Role of Osteocyte-derived Insulin-Like Growth Factor I in Developmental Growth, Modeling, Remodeling, and Regeneration of the Bone.Signaling pathways affecting skeletal health.Anabolic effects of IGF-1 signaling on the skeleton.Skeletal effects of growth hormone and insulin-like growth factor-I therapy.External mechanical microstimuli modulate the osseointegration of titanium implants in rat tibiae.IGF-1 signaling mediated cell-specific skeletal mechano-transduction.Serum sclerostin decreases following 12months of resistance- or jump-training in men with low bone mass.The RhoGAP Myo9b Promotes Bone Growth by Mediating Osteoblastic Responsiveness to IGF-1.Liver-derived IGF-I regulates cortical bone mass but is dispensable for the osteogenic response to mechanical loading in female mice.Role of IGF-I and Efn-Eph Signaling in Skeletal Metabolism.The osteoprogenitor-specific loss of ephrinB1 results in an osteoporotic phenotype affecting the balance between bone formation and resorption

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Conditional disruption of IGF-I gene in type 1α collagen-expressing cells shows an essential role of IGF-I in skeletal anabolic response to loading

http://www.wikidata.org/entity/Q35601229

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2011 nî lūn-bûn

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AJPENDO.00440.2011

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American Journal of Physiology - Endocrinology and Metabolism

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Conditional disruption of IGF- ...... l anabolic response to loading

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Chandrasekhar Kesavan

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Jon E Wergedal

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Subburaman Mohan

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P2860

Mechanical strain on osteoblasts activates autophosphorylation of focal adhesion kinase and proline-rich tyrosine kinase 2 tyrosine sites involved in ERK activation

A time course of bone response to jump exercise in C57BL/6J mice.

Targeted disruption of nuclear factor erythroid-derived 2-like 1 in osteoblasts reduces bone size and bone formation in mice.

Ephrin B1 regulates bone marrow stromal cell differentiation and bone formation by influencing TAZ transactivation via complex formation with NHERF1.

Loading-related regulation of gene expression in bone in the contexts of estrogen deficiency, lack of estrogen receptor alpha and disuse

Conditional deletion of insulin-like growth factor-I in collagen type 1alpha2-expressing cells results in postnatal lethality and a dramatic reduction in bone accretion

Noninvasive loading of the murine tibia: an in vivo model for the study of mechanotransduction.

EphrinB2 regulation by PTH and PTHrP revealed by molecular profiling in differentiating osteoblasts.

Aged mice have enhanced endocortical response and normal periosteal response compared with young-adult mice following 1 week of axial tibial compression.

The impact of skeletal unloading on bone formation.

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E1191-7

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10.1152/AJPENDO.00440.2011

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21878662

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3233773

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