Mitochondrial calcium uptake capacity as a therapeutic target in the R6/2 mouse model of Huntington's disease. - Wikidata - awgldk - TriplyDB

Mitochondrial calcium uptake capacity as a therapeutic target in the R6/2 mouse model of Huntington's disease.

Mitochondrial calcium uptake capacity as a therapeutic target in the R6/2 mouse model of Huntington's disease.

http://www.wikidata.org/entity/Q34046887

about

Tissue transglutaminase overexpression does not modify the disease phenotype of the R6/2 mouse model of Huntington's disease Mouse models of polyglutamine diseases in therapeutic approaches: review and data table. Part II.Neurodevelopmental impairment following neonatal hyperoxia in the mouse.Metabolic state determines sensitivity to cellular stress in Huntington disease: normalization by activation of PPARγ.Implantation of undifferentiated and pre-differentiated human neural stem cells in the R6/2 transgenic mouse model of Huntington's disease Altered Ca(2+) signaling in skeletal muscle fibers of the R6/2 mouse, a model of Huntington's disease Ca(2+) handling in isolated brain mitochondria and cultured neurons derived from the YAC128 mouse model of Huntington's disease Disruption of Purkinje cell function prior to huntingtin accumulation and cell loss in an animal model of Huntington disease.Mitochondrial Ca(2+) and neurodegeneration Purkinje cell dysfunction and loss in a knock-in mouse model of Huntington disease Allelic series of Huntington's disease knock-in mice reveals expression discorrelates.Hyperactivity and cortical disinhibition in mice with restricted expression of mutant huntingtin to parvalbumin-positive cells.Mitochondrial permeability transition pore induces mitochondria injury in Huntington disease.Oxidative metabolism and Ca2+ handling in isolated brain mitochondria and striatal neurons from R6/2 mice, a model of Huntington's disease.Mitochondrial dysfunction and nicotinamide dinucleotide catabolism as mechanisms of cell death and promising targets for neuroprotection.Huntington's disease, calcium, and mitochondria.Mutant Huntingtin and Elusive Defects in Oxidative Metabolism and Mitochondrial Calcium Handling.Towards an Understanding of Energy Impairment in Huntington's Disease Brain.Adeno-Associated Viral Vector Serotype DJ-Mediated Overexpression of N171-82Q-Mutant Huntingtin in the Striatum of Juvenile Mice Is a New Model for Huntington's Disease.

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Mitochondrial calcium uptake capacity as a therapeutic target in the R6/2 mouse model of Huntington's disease.

http://www.wikidata.org/entity/Q34046887

description

2010 nî lūn-bûn

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2010 թուականի Յունիսին հրատարակուած գիտական յօդուած

@hyw

2010 թվականի հունիսին հրատարակված գիտական հոդված

@hy

2010年の論文

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2010年論文

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2010年論文

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2010年論文

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2010年論文

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2010年論文

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2010年论文

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name

Mitochondrial calcium uptake c ...... model of Huntington's disease.

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Mitochondrial calcium uptake c ...... model of Huntington's disease.

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Mitochondrial calcium uptake c ...... model of Huntington's disease.

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Mitochondrial calcium uptake c ...... model of Huntington's disease.

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Mitochondrial calcium uptake c ...... model of Huntington's disease.

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Mitochondrial calcium uptake c ...... model of Huntington's disease.

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Mitochondrial calcium uptake c ...... model of Huntington's disease.

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Human Molecular Genetics

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Mitochondrial calcium uptake c ...... model of Huntington's disease.

@en

P2093

Andrew Kneynsberg

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Ashish Kumar

http://www.w3.org/2001/XMLSchema#string

Giselle M Perry

http://www.w3.org/2001/XMLSchema#string

Mary Y Heng

http://www.w3.org/2001/XMLSchema#string

Mathieu Lesort

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Peter J Detloff

http://www.w3.org/2001/XMLSchema#string

Roger L Albin

http://www.w3.org/2001/XMLSchema#string

Sara Tallaksen-Greene

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Thomas van Groen

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P2860

The Huntington's disease protein interacts with p53 and CREB-binding protein and represses transcription

Huntington's disease genetics

Huntingtin is a cytoplasmic protein associated with vesicles in human and rat brain neurons

A novel gene containing a trinucleotide repeat that is expanded and unstable on Huntington's disease chromosomes.

Cyclophilin D-dependent mitochondrial permeability transition regulates some necrotic but not apoptotic cell death

Loss of cyclophilin D reveals a critical role for mitochondrial permeability transition in cell death

Voltage-dependent anion channels are dispensable for mitochondrial-dependent cell death

Long glutamine tracts cause nuclear localization of a novel form of huntingtin in medium spiny striatal neurons in HdhQ92 and HdhQ111 knock-in mice

Age-dependent changes in the calcium sensitivity of striatal mitochondria in mouse models of Huntington's Disease

Mitochondrial targeted cyclophilin D protects cells from cell death by peptidyl prolyl isomerization

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3354-3371

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scholarly article

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10.1093/HMG/DDQ247

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17

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19

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2010-06-17T00:00:00Z

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44683241

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20558522

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Huntington disease

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2916705

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