Prediction of relative in vivo metabolite exposure from in vitro data using two model drugs: dextromethorphan and omeprazole.

Prediction of relative in vivo metabolite exposure from in vitro data using two model drugs: dextromethorphan and omeprazole.

Item
http://www.wikidata.org/entity/Q34051253
Inhibition of CYP2C19 and CYP3A4 by omeprazole metabolites and their contribution to drug-drug interactionsMechanistic Modeling to Predict Midazolam Metabolite Exposure from In Vitro Data.In vitro analysis and quantitative prediction of efavirenz inhibition of eight cytochrome P450 (CYP) enzymes: major effects on CYPs 2B6, 2C8, 2C9 and 2C19Hepatic Cyp2d and Cyp26a1 mRNAs and activities are increased during mouse pregnancy.A physiologically based pharmacokinetic model to predict disposition of CYP2D6 and CYP1A2 metabolized drugs in pregnant women.In vitro to in vivo extrapolation of the complex drug-drug interaction of bupropion and its metabolites with CYP2D6; simultaneous reversible inhibition and CYP2D6 downregulation.Pharmacokinetic and Pharmacodynamic Modeling Analysis of Intravenous Esomeprazole in Healthy Volunteers.High-throughput quantitative and qualitative analysis of microsomal incubations by cocktail analysis with an ultraperformance liquid chromatography-quadrupole time-of-flight mass spectrometer system.Morphological behaviour and metabolic capacity of cryopreserved human primary hepatocytes cultivated in a perfused multiwell device.Pharmacokinetic comparison between the long-term anesthetized, short-term anesthetized and conscious rat models in nasal drug delivery.Use of Human Plasma Samples to Identify Circulating Drug Metabolites that Inhibit Cytochrome P450 Enzymes.
P2860

Prediction of relative in vivo metabolite exposure from in vitro data using two model drugs: dextromethorphan and omeprazole.

Item
http://www.wikidata.org/entity/Q34051253
description
2011 nî lūn-bûn
@nan
2011 թուականի Հոկտեմբերին հրատարակուած գիտական յօդուած
@hyw
2011 թվականի հոտեմբերին հրատարակված գիտական հոդված
@hy
2011年の論文
@ja
2011年論文
@yue
2011年論文
@zh-hant
2011年論文
@zh-hk
2011年論文
@zh-mo
2011年論文
@zh-tw
2011年论文
@wuu
name
Prediction of relative in vivo ...... xtromethorphan and omeprazole.
@ast
Prediction of relative in vivo ...... xtromethorphan and omeprazole.
@en
Prediction of relative in vivo ...... xtromethorphan and omeprazole.
@nl
type
label
Prediction of relative in vivo ...... xtromethorphan and omeprazole.
@ast
Prediction of relative in vivo ...... xtromethorphan and omeprazole.
@en
Prediction of relative in vivo ...... xtromethorphan and omeprazole.
@nl
prefLabel
Prediction of relative in vivo ...... xtromethorphan and omeprazole.
@ast
Prediction of relative in vivo ...... xtromethorphan and omeprazole.
@en
Prediction of relative in vivo ...... xtromethorphan and omeprazole.
@nl
P1433
P1476
P2093
P2860
P304
P31
P356
P433
P478
P577
P5875
P698
P932
P356
P1433
P1476
Prediction of relative in vivo ...... xtromethorphan and omeprazole.
@en
P2093
P2860
P304
P31
P356
P433
P478
P577
P5875
P698
P932