Comparative contribution to dextromethorphan metabolism by cytochrome P450 isoforms in vitro: can dextromethorphan be used as a dual probe for both CTP2D6 and CYP3A activities?
about
Optimization of the bacterial cytochrome P450 BM3 system for the production of human drug metabolitesPrediction of relative in vivo metabolite exposure from in vitro data using two model drugs: dextromethorphan and omeprazole.Population pharmacokinetic modelling to assess the impact of CYP2D6 and CYP3A metabolic phenotypes on the pharmacokinetics of tamoxifen and endoxifenModulation of CYP2D6 and CYP3A4 metabolic activities by Ferula asafetida resinEvaluation of CYP2D6 enzyme activity using a 13C-dextromethorphan breath test in women receiving adjuvant tamoxifen.Rapid and quantitative measurement of metabolic stability without chromatography or mass spectrometryA comparison of relative abundance, activity factor and inhibitory monoclonal antibody approaches in the characterization of human CYP enzymologyDevelopment of an in vitro system with human liver microsomes for phenotyping of CYP2C9 genetic polymorphisms with a mechanism-based inactivatorThe Discriminatory Value of CYP2D6 Genotyping in Predicting the Dextromethorphan/Dextrorphan Phenotype in Women with Breast Cancer.Stable expression of human cytochrome P450 2D6*10 in HepG2 cells.A physiologically based pharmacokinetic model to predict disposition of CYP2D6 and CYP1A2 metabolized drugs in pregnant women.Effect of Garden Cress Seeds Powder and Its Alcoholic Extract on the Metabolic Activity of CYP2D6 and CYP3A4.Contextualizing Hepatocyte Functionality of Cryopreserved HepaRG Cell CulturesCharacterization of increased drug metabolism activity in dimethyl sulfoxide (DMSO)-treated Huh7 hepatoma cellsApplicability of second-generation upcyte® human hepatocytes for use in CYP inhibition and induction studies.In vitro modulatory effects of Terminalia arjuna, arjunic acid, arjunetin and arjungenin on CYP3A4, CYP2D6 and CYP2C9 enzyme activity in human liver microsomes.Endogenous and xenobiotic metabolic stability of primary human hepatocytes in long-term 3D spheroid cultures revealed by a combination of targeted and untargeted metabolomics.Role of conserved Asp293 of cytochrome P450 2C9 in substrate recognition and catalytic activity.Dicloxacillin induces CYP2C19, CYP2C9 and CYP3A4 in vivo and in vitro.CYP2D6 protein level is the major contributor to inter-individual variability in CYP2D6-mediated drug metabolism in healthy human liver tissue.Comparative metabolism of xenobiotic chemicals by cytochrome P450s in the nematode Caenorhabditis elegans
P2860
Q27027286-C87D8AE7-D28A-45BD-BB3D-419A1117109FQ34051253-BBA73018-03B7-481C-B853-C101770B94C6Q34571065-FD2F829E-F202-4F62-95A6-B57A0FA95084Q34800242-EDE8DE46-06A9-4006-A77E-C55ECB081C64Q35168556-8CB0821A-968C-4E9C-8133-0028A10746C4Q35231752-048C8735-BCA5-48F6-A474-45FC165B4AC5Q35846700-71EDB3D9-0703-45FA-861E-6A68D9F1F5A5Q35846894-A70DFDFD-A712-4F54-B5EA-BC14503BB7E5Q35909573-7893038B-8300-4CCF-8948-398E11A40E4FQ36474404-D4022B39-82FF-4295-BDCB-831B0B07F8A6Q36717181-30FEE6E8-DF82-45AB-898C-FC0E71FF0A82Q37664498-25987899-475F-46D7-AF35-89C67505E289Q39659058-9CCDDDF6-BA96-4CD9-AA88-EFB56B3F69A0Q39873984-F9880370-6DCF-49FB-89E8-F14118975B1EQ40376125-8DA17E80-83B0-4FB4-802E-075A6E1BA97DQ41680453-00819026-CEC3-4EBD-9935-A6FDFB9F7A82Q41870452-28CA9174-CDAC-4222-98A9-2C9C4BE51628Q43002752-AB31051A-DD22-4D51-9694-3CEA775DA124Q48360626-6BEFF9B6-8C98-49DE-B360-A860767099B2Q49933391-00D50DF5-1593-41F9-A84E-EC9C4122BCE5Q58761893-CF705E30-8831-401E-B726-AF81B4810DBB
P2860
Comparative contribution to dextromethorphan metabolism by cytochrome P450 isoforms in vitro: can dextromethorphan be used as a dual probe for both CTP2D6 and CYP3A activities?
description
2001 nî lūn-bûn
@nan
2001 թուականի Նոյեմբերին հրատարակուած գիտական յօդուած
@hyw
2001 թվականի նոյեմբերին հրատարակված գիտական հոդված
@hy
2001年の論文
@ja
2001年論文
@yue
2001年論文
@zh-hant
2001年論文
@zh-hk
2001年論文
@zh-mo
2001年論文
@zh-tw
2001年论文
@wuu
name
Comparative contribution to de ...... h CTP2D6 and CYP3A activities?
@ast
Comparative contribution to de ...... h CTP2D6 and CYP3A activities?
@en
Comparative contribution to de ...... h CTP2D6 and CYP3A activities?
@nl
type
label
Comparative contribution to de ...... h CTP2D6 and CYP3A activities?
@ast
Comparative contribution to de ...... h CTP2D6 and CYP3A activities?
@en
Comparative contribution to de ...... h CTP2D6 and CYP3A activities?
@nl
prefLabel
Comparative contribution to de ...... h CTP2D6 and CYP3A activities?
@ast
Comparative contribution to de ...... h CTP2D6 and CYP3A activities?
@en
Comparative contribution to de ...... h CTP2D6 and CYP3A activities?
@nl
P1476
Comparative contribution to de ...... h CTP2D6 and CYP3A activities?
@en
P2093
P304
P577
2001-11-01T00:00:00Z