SIRT1 reduces endothelial activation without affecting vascular function in ApoE-/- mice.
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The endothelium abridges insulin resistance to premature agingRole of sirtuins in ischemia-reperfusion injuryThe role of oxidative stress and inflammation in cardiovascular agingFibrocalcific aortic valve disease: opportunity to understand disease mechanisms using mouse modelsMitochondria and cardiovascular agingXenohormetic and anti-aging activity of secoiridoid polyphenols present in extra virgin olive oil: a new family of gerosuppressant agentsCalcific aortic valve stenosis: methods, models, and mechanismsThe class III histone deacetylase sirtuin 1 in immune suppression and its therapeutic potential in rheumatoid arthritis.Anti-atherogenic properties of resveratrol: 4-week resveratrol administration associated with serum concentrations of SIRT1, adiponectin, S100A8/A9 and VSMCs contractility in a rat model.Inhibition of SIRT1 impairs the accumulation and transcriptional activity of HIF-1α protein under hypoxic conditions.Metformin is not just an antihyperglycaemic drug but also has protective effects on the vascular endothelium.The endothelium: influencing vascular smooth muscle in many ways.Redox factor-1 activates endothelial SIRTUIN1 through reduction of conserved cysteine sulfhydryls in its deacetylase domain.SIRT1 gene polymorphisms affect the protein expression in cardiovascular diseases.Oxidative stress activates endothelial innate immunity via sterol regulatory element binding protein 2 (SREBP2) transactivation of microRNA-92aThe involvement of NFAT transcriptional activity suppression in SIRT1-mediated inhibition of COX-2 expression induced by PMA/Ionomycin.Early hyperlipidemia promotes endothelial activation via a caspase-1-sirtuin 1 pathwayDietary α-linolenic acid diminishes experimental atherogenesis and restricts T cell-driven inflammation.Inflammatory cause of metabolic syndrome via brain stress and NF-κB.Involvement of miR-Let7A in inflammatory response and cell survival/apoptosis regulated by resveratrol in THP-1 macrophage.An autoregulatory loop reverts the mechanosensitive Sirt1 induction by EGR1 in skeletal muscle cellsOn the epigenetics of vascular regulation and diseaseMetabolomic profiling of the heart during acute ischemic preconditioning reveals a role for SIRT1 in rapid cardioprotective metabolic adaptation.Sirtuins and renal diseases: relationship with aging and diabetic nephropathy.Protective effects of sirtuins in cardiovascular diseases: from bench to bedsideSirt1 is involved in decreased bone formation in aged apolipoprotein E-deficient mice.Global Gene Expression Profiling Reveals Functional Importance of Sirt2 in Endothelial Cells under Oxidative Stress.Sirtuins, Cell Senescence, and Vascular AgingSIRT1: recent lessons from mouse models.Recent progress in genetics of aging, senescence and longevity: focusing on cancer-related genes.Pharmacological Strategies to Retard Cardiovascular AgingMetformin regulates oxLDL-facilitated endothelial dysfunction by modulation of SIRT1 through repressing LOX-1-modulated oxidative signalingPotential mechanisms linking atherosclerosis and increased cardiovascular risk in COPD: focus on Sirtuins.SIRT6 protects against endothelial dysfunction and atherosclerosis in miceSirT1 regulation of antioxidant genes is dependent on the formation of a FoxO3a/PGC-1α complexThe protective role of Sirt1 in vascular tissue: its relationship to vascular aging and atherosclerosis.Role of mitochondrial dysfunction and altered autophagy in cardiovascular aging and disease: from mechanisms to therapeutics.Deletion of Sirt3 does not affect atherosclerosis but accelerates weight gain and impairs rapid metabolic adaptation in LDL receptor knockout mice: implications for cardiovascular risk factor development.Long-term caloric restriction in ApoE-deficient mice results in neuroprotection via Fgf21-induced AMPK/mTOR pathway.MKK3 regulates mitochondrial biogenesis and mitophagy in sepsis-induced lung injury.
P2860
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P2860
SIRT1 reduces endothelial activation without affecting vascular function in ApoE-/- mice.
description
2010 nî lūn-bûn
@nan
2010 թուականի Յունիսին հրատարակուած գիտական յօդուած
@hyw
2010 թվականի հունիսին հրատարակված գիտական հոդված
@hy
2010年の論文
@ja
2010年論文
@yue
2010年論文
@zh-hant
2010年論文
@zh-hk
2010年論文
@zh-mo
2010年論文
@zh-tw
2010年论文
@wuu
name
SIRT1 reduces endothelial activation without affecting vascular function in ApoE-/- mice.
@ast
SIRT1 reduces endothelial activation without affecting vascular function in ApoE-/- mice.
@en
SIRT1 reduces endothelial activation without affecting vascular function in ApoE-/- mice.
@nl
type
label
SIRT1 reduces endothelial activation without affecting vascular function in ApoE-/- mice.
@ast
SIRT1 reduces endothelial activation without affecting vascular function in ApoE-/- mice.
@en
SIRT1 reduces endothelial activation without affecting vascular function in ApoE-/- mice.
@nl
prefLabel
SIRT1 reduces endothelial activation without affecting vascular function in ApoE-/- mice.
@ast
SIRT1 reduces endothelial activation without affecting vascular function in ApoE-/- mice.
@en
SIRT1 reduces endothelial activation without affecting vascular function in ApoE-/- mice.
@nl
P2093
P2860
P356
P1433
P1476
SIRT1 reduces endothelial activation without affecting vascular function in ApoE-/- mice.
@en
P2093
Alexander Breitenstein
Chad E Brokopp
Christian Besler
Christian M Matter
Christine Lohmann
Christoph Handschin
Felix C Tanner
Kathrin Heinrich
Nicola Schäfer
Sokrates Stein
P2860
P304
P356
10.18632/AGING.100162
P577
2010-06-01T00:00:00Z