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Metaboloepigenetics: interrelationships between energy metabolism and epigenetic control of gene expressionEmerging therapeutic roles for NAD(+) metabolism in mitochondrial and age-related disordersEpigenetic mechanisms underlying the link between non-alcoholic fatty liver diseases and nutritionSirtuin 1 and sirtuin 3: physiological modulators of metabolismSirtuins as regulators of metabolism and healthspanCommon features of chromatin in aging and cancer: cause or coincidence?Targeting sirtuin 1 to improve metabolism: all you need is NAD(+)?Metabolism, longevity and epigeneticsProgramming and Reprogramming Cellular Age in the Era of Induced PluripotencyLysine deacetylase (KDAC) regulatory pathways: an alternative approach to selective modulationPancreas-Specific Sirt1-Deficiency in Mice Compromises Beta-Cell Function without Development of HyperglycemiaModulation of tumorigenesis by dietary intervention is not mediated by SIRT1 catalytic activityUndercover: gene control by metabolites and metabolic enzymesNew Insights for Oxidative Stress and Diabetes MellitusThe physiological roles of Sirt1 in skeletal muscleXenohormetic and anti-aging activity of secoiridoid polyphenols present in extra virgin olive oil: a new family of gerosuppressant agentsGermline deletion of pantothenate kinases 1 and 2 reveals the key roles for CoA in postnatal metabolismBCL6 controls neurogenesis through Sirt1-dependent epigenetic repression of selective Notch targetsEnterocyte-specific inactivation of SIRT1 reduces tumor load in the APC(+/min) mouse model.β2-AR activation induces chemoresistance by modulating p53 acetylation through upregulating Sirt1 in cervical cancer cells.The ways and means that fine tune Sirt1 activity.Dual role of SIRT1 in UVB-induced skin tumorigenesis.Identification of common genetic modifiers of neurodegenerative diseases from an integrative analysis of diverse genetic screens in model organismsAgeing: longevity hits a roadblock.The cAMP/PKA pathway rapidly activates SIRT1 to promote fatty acid oxidation independently of changes in NAD(+).Leucine Modulates Mitochondrial Biogenesis and SIRT1-AMPK Signaling in C2C12 Myotubes.SIRT1 deacetylates TopBP1 and modulates intra-S-phase checkpoint and DNA replication origin firingThe multifunctional sorting protein PACS-2 regulates SIRT1-mediated deacetylation of p53 to modulate p21-dependent cell-cycle arrest.Sorting out functions of sirtuins in cancerSRT1720 induces lysosomal-dependent cell death of breast cancer cells.New comparative genomics approach reveals a conserved health span signature across species.Hepatic Sirt1 deficiency in mice impairs mTorc2/Akt signaling and results in hyperglycemia, oxidative damage, and insulin resistance.The role of sirtuins in modulating redox stressorsTranslating cell survival and cell longevity into treatment strategies with SIRT1Targeting cardiovascular disease with novel SIRT1 pathways.Resveratrol triggers the pro-apoptotic endoplasmic reticulum stress response and represses pro-survival XBP1 signaling in human multiple myeloma cells.Perspectives of Targeting mTORC1-S6K1 in Cardiovascular AgingThe c-MYC oncoprotein, the NAMPT enzyme, the SIRT1-inhibitor DBC1, and the SIRT1 deacetylase form a positive feedback loop.SIRT1: new avenues of discovery for disorders of oxidative stressMating-type genes and MAT switching in Saccharomyces cerevisiae.
P2860
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P2860
description
2010 nî lūn-bûn
@nan
2010年の論文
@ja
2010年論文
@yue
2010年論文
@zh-hant
2010年論文
@zh-hk
2010年論文
@zh-mo
2010年論文
@zh-tw
2010年论文
@wuu
2010年论文
@zh
2010年论文
@zh-cn
name
SIRT1: recent lessons from mouse models.
@en
type
label
SIRT1: recent lessons from mouse models.
@en
prefLabel
SIRT1: recent lessons from mouse models.
@en
P2860
P356
P1476
SIRT1: recent lessons from mouse models
@en
P2093
Daniel Herranz
Manuel Serrano
P2860
P2888
P304
P356
10.1038/NRC2962
P407
P577
2010-11-24T00:00:00Z