Global relevance of Aire binding to hypomethylated lysine-4 of histone-3.
about
Aire and T cell developmentThe Thymic Orchestration Involving Aire, miRNAs, and Cell-Cell Interactions during the Induction of Central ToleranceAIRE-PHD fingers are structural hubs to maintain the integrity of chromatin-associated interactomeThe role of epigenetic mechanisms and processes in autoimmune disordersControl of central and peripheral tolerance by Aire.Epigenetic regulation of promiscuous gene expression in thymic medullary epithelial cells.Exploring PHD fingers and H3K4me0 interactions with molecular dynamics simulations and binding free energy calculations: AIRE-PHD1, a comparative study.Epigenetics of autoantigens: new opportunities for therapy of autoimmune diseases.Population and single-cell genomics reveal the Aire dependency, relief from Polycomb silencing, and distribution of self-antigen expression in thymic epithelia.Aire unleashes stalled RNA polymerase to induce ectopic gene expression in thymic epithelial cellsUnmodified histone H3K4 and DNA-dependent protein kinase recruit autoimmune regulator to target genes.Central tolerance to self revealed by the autoimmune regulator.Immune tolerance. Regulatory T cells generated early in life play a distinct role in maintaining self-tolerance.Aire's plant homeodomain(PHD)-2 is critical for induction of immunological toleranceThe role of Aire in clonal selection.Contrasting models for the roles of Aire in the differentiation program of epithelial cells in the thymic medulla.Models of aire-dependent gene regulation for thymic negative selection.Which model better fits the role of aire in the establishment of self-tolerance: the transcription model or the maturation model?The transcriptional regulator Aire coopts the repressive ATF7ip-MBD1 complex for the induction of immunotolerance.Prdm1 Regulates Thymic Epithelial Function To Prevent Autoimmunity.AIRE expands: new roles in immune tolerance and beyond.Generation of diversity in thymic epithelial cells.Aire Inhibits the Generation of a Perinatal Population of Interleukin-17A-Producing γδ T Cells to Promote Immunologic Tolerance.Rapid chromatin repression by Aire provides precise control of immune tolerance.Twenty Years of AIRE.Role of Polyamines in Immune Cell Functions.
P2860
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P2860
Global relevance of Aire binding to hypomethylated lysine-4 of histone-3.
description
2010 nî lūn-bûn
@nan
2010 թուականի Յուլիսին հրատարակուած գիտական յօդուած
@hyw
2010 թվականի հուլիսին հրատարակված գիտական հոդված
@hy
2010年の論文
@ja
2010年論文
@yue
2010年論文
@zh-hant
2010年論文
@zh-hk
2010年論文
@zh-mo
2010年論文
@zh-tw
2010年论文
@wuu
name
Global relevance of Aire binding to hypomethylated lysine-4 of histone-3.
@ast
Global relevance of Aire binding to hypomethylated lysine-4 of histone-3.
@en
Global relevance of Aire binding to hypomethylated lysine-4 of histone-3.
@nl
type
label
Global relevance of Aire binding to hypomethylated lysine-4 of histone-3.
@ast
Global relevance of Aire binding to hypomethylated lysine-4 of histone-3.
@en
Global relevance of Aire binding to hypomethylated lysine-4 of histone-3.
@nl
prefLabel
Global relevance of Aire binding to hypomethylated lysine-4 of histone-3.
@ast
Global relevance of Aire binding to hypomethylated lysine-4 of histone-3.
@en
Global relevance of Aire binding to hypomethylated lysine-4 of histone-3.
@nl
P2093
P2860
P356
P1476
Global relevance of Aire binding to hypomethylated lysine-4 of histone-3.
@en
P2093
Andrew S Koh
Christophe Benoist
Diane Mathis
Robert E Kingston
P2860
P304
13016-13021
P356
10.1073/PNAS.1004436107
P407
P577
2010-07-06T00:00:00Z