Global relevance of Aire binding to hypomethylated lysine-4 of histone-3. - Wikidata - awgldk - TriplyDB

Global relevance of Aire binding to hypomethylated lysine-4 of histone-3.

Global relevance of Aire binding to hypomethylated lysine-4 of histone-3.

http://www.wikidata.org/entity/Q34059326

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Aire and T cell development The Thymic Orchestration Involving Aire, miRNAs, and Cell-Cell Interactions during the Induction of Central Tolerance AIRE-PHD fingers are structural hubs to maintain the integrity of chromatin-associated interactome The role of epigenetic mechanisms and processes in autoimmune disorders Control of central and peripheral tolerance by Aire.Epigenetic regulation of promiscuous gene expression in thymic medullary epithelial cells.Exploring PHD fingers and H3K4me0 interactions with molecular dynamics simulations and binding free energy calculations: AIRE-PHD1, a comparative study.Epigenetics of autoantigens: new opportunities for therapy of autoimmune diseases.Population and single-cell genomics reveal the Aire dependency, relief from Polycomb silencing, and distribution of self-antigen expression in thymic epithelia.Aire unleashes stalled RNA polymerase to induce ectopic gene expression in thymic epithelial cells Unmodified histone H3K4 and DNA-dependent protein kinase recruit autoimmune regulator to target genes.Central tolerance to self revealed by the autoimmune regulator.Immune tolerance. Regulatory T cells generated early in life play a distinct role in maintaining self-tolerance.Aire's plant homeodomain(PHD)-2 is critical for induction of immunological tolerance The role of Aire in clonal selection.Contrasting models for the roles of Aire in the differentiation program of epithelial cells in the thymic medulla.Models of aire-dependent gene regulation for thymic negative selection.Which model better fits the role of aire in the establishment of self-tolerance: the transcription model or the maturation model?The transcriptional regulator Aire coopts the repressive ATF7ip-MBD1 complex for the induction of immunotolerance.Prdm1 Regulates Thymic Epithelial Function To Prevent Autoimmunity.AIRE expands: new roles in immune tolerance and beyond.Generation of diversity in thymic epithelial cells.Aire Inhibits the Generation of a Perinatal Population of Interleukin-17A-Producing γδ T Cells to Promote Immunologic Tolerance.Rapid chromatin repression by Aire provides precise control of immune tolerance.Twenty Years of AIRE.Role of Polyamines in Immune Cell Functions.

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P2860

Global relevance of Aire binding to hypomethylated lysine-4 of histone-3.

http://www.wikidata.org/entity/Q34059326

description

2010 nî lūn-bûn

@nan

2010 թուականի Յուլիսին հրատարակուած գիտական յօդուած

@hyw

2010 թվականի հուլիսին հրատարակված գիտական հոդված

@hy

2010年の論文

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2010年論文

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2010年論文

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2010年論文

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2010年論文

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2010年論文

@zh-tw

2010年论文

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name

Global relevance of Aire binding to hypomethylated lysine-4 of histone-3.

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Global relevance of Aire binding to hypomethylated lysine-4 of histone-3.

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Global relevance of Aire binding to hypomethylated lysine-4 of histone-3.

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type

label

Global relevance of Aire binding to hypomethylated lysine-4 of histone-3.

@ast

Global relevance of Aire binding to hypomethylated lysine-4 of histone-3.

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Global relevance of Aire binding to hypomethylated lysine-4 of histone-3.

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prefLabel

Global relevance of Aire binding to hypomethylated lysine-4 of histone-3.

@ast

Global relevance of Aire binding to hypomethylated lysine-4 of histone-3.

@en

Global relevance of Aire binding to hypomethylated lysine-4 of histone-3.

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PNAS.1004436107

P1433

Proceedings of the National Academy of Sciences of the United States of America

P1476

Global relevance of Aire binding to hypomethylated lysine-4 of histone-3.

@en

P2093

Andrew S Koh

http://www.w3.org/2001/XMLSchema#string

Christophe Benoist

http://www.w3.org/2001/XMLSchema#string

Diane Mathis

http://www.w3.org/2001/XMLSchema#string

Robert E Kingston

http://www.w3.org/2001/XMLSchema#string

P2860

Dnmt3L cooperates with the Dnmt3 family of de novo DNA methyltransferases to establish maternal imprints in mice

Methylation of histone H3R2 by PRMT6 and H3K4 by an MLL complex are mutually exclusive

Aire's partners in the molecular control of immunological tolerance

Structure and site-specific recognition of histone H3 by the PHD finger of human autoimmune regulator

The autoimmune regulator PHD finger binds to non-methylated histone H3K4 to activate gene expression

DNMT3L connects unmethylated lysine 4 of histone H3 to de novo methylation of DNA

Yng1 PHD Finger Binding to H3 Trimethylated at K4 Promotes NuA3 HAT Activity at K14 of H3 and Transcription at a Subset of Targeted ORFs

Recognition of unmethylated histone H3 lysine 4 links BHC80 to LSD1-mediated gene repression

The solution structure of the first PHD finger of autoimmune regulator in complex with non-modified histone H3 tail reveals the antagonistic role of H3R2 methylation

RBP2 belongs to a family of demethylases, specific for tri-and dimethylated lysine 4 on histone 3

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13016-13021

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scholarly article

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10.1073/PNAS.1004436107

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29

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107

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2010-07-06T00:00:00Z

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45113501

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20615959

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2919944

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