Elevated PDGFRB gene copy number gain is prognostic for improved survival outcomes in resected malignant pleural mesothelioma
about
Platelet-derived growth factor receptor/platelet-derived growth factor (PDGFR/PDGF) system is a prognostic and treatment response biomarker with multifarious therapeutic targets in cancers.Inhibition of the platelet-derived growth factor receptor beta (PDGFRB) using gene silencing, crenolanib besylate, or imatinib mesylate hampers the malignant phenotype of mesothelioma cell lines.The platelet-derived growth factors (PDGFs) and their receptors (PDGFRs) are major players in oncogenesis, drug resistance, and attractive oncologic targets in cancer.Involvement of platelet-derived growth factor ligands and receptors in tumorigenesis.Heterogeneous Contributing Factors in MPM Disease Development and Progression: Biological Advances and Clinical Implications.
P2860
Elevated PDGFRB gene copy number gain is prognostic for improved survival outcomes in resected malignant pleural mesothelioma
description
2014 nî lūn-bûn
@nan
2014 թուականի Փետրուարին հրատարակուած գիտական յօդուած
@hyw
2014 թվականի փետրվարին հրատարակված գիտական հոդված
@hy
2014年の論文
@ja
2014年論文
@yue
2014年論文
@zh-hant
2014年論文
@zh-hk
2014年論文
@zh-mo
2014年論文
@zh-tw
2014年论文
@wuu
name
Elevated PDGFRB gene copy numb ...... malignant pleural mesothelioma
@ast
Elevated PDGFRB gene copy numb ...... malignant pleural mesothelioma
@en
Elevated PDGFRB gene copy numb ...... malignant pleural mesothelioma
@nl
type
label
Elevated PDGFRB gene copy numb ...... malignant pleural mesothelioma
@ast
Elevated PDGFRB gene copy numb ...... malignant pleural mesothelioma
@en
Elevated PDGFRB gene copy numb ...... malignant pleural mesothelioma
@nl
prefLabel
Elevated PDGFRB gene copy numb ...... malignant pleural mesothelioma
@ast
Elevated PDGFRB gene copy numb ...... malignant pleural mesothelioma
@en
Elevated PDGFRB gene copy numb ...... malignant pleural mesothelioma
@nl
P2093
P2860
P1476
Elevated PDGFRB gene copy numb ...... malignant pleural mesothelioma
@en
P2093
Anne S Tsao
Cesar Moran
David Rice
Elisabetta Kuhn
J Jack Lee
Junya Fujimoto
Milind Suraokar
Nusrat Harun
Reza Mehran
P2860
P304
P356
10.1016/J.ANNDIAGPATH.2014.02.005
P577
2014-02-20T00:00:00Z