Production of platelet-derived growth factor-like molecules and reduced expression of platelet-derived growth factor receptors accompany transformation by a wide spectrum of agents
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Platelet-derived growth factor A chain: gene structure, chromosomal location, and basis for alternative mRNA splicingStructural and functional aspects of platelet-derived growth factorA novel functional genomics approach identifies mTERT as a suppressor of fibroblast transformation.The v-sis/PDGF-2 transforming gene product localizes to cell membranes but is not a secretory protein.The B chain of PDGF alone is sufficient for mitogenesis.Elevated PDGFRB gene copy number gain is prognostic for improved survival outcomes in resected malignant pleural mesotheliomaCharacterization of biologically active, platelet-derived growth factor-like molecules produced by murine erythroid cells in vitro and in vivo.Role of a tumor-suppressor gene in the negative control of anchorage-independent growth of Syrian hamster cells.Synthesis and secretion of platelet-derived growth factor by human breast cancer cell linesProduction of transforming growth factor alpha in human pancreatic cancer cells: evidence for a superagonist autocrine cyclePeptide growth factors and inflammation, tissue repair, and cancer.Platelet-derived growth factor enhances in vitro erythropoiesis via stimulation of mesenchymal cells.Constitutive and inducible secretion of platelet-derived growth factor analogs by human leukemic cell lines coexpressing erythroid and megakaryocytic markers.Activation of growth factor secretion in tumorigenic states of breast cancer induced by 17 beta-estradiol or v-Ha-ras oncogeneOccurrence and control of sporadic proliferation in growth arrested Swiss 3T3 feeder cells.Production of platelet-derived growth factorlike protein by rat mesangial cells in cultureInduction of c-sis mRNA and activity similar to platelet-derived growth factor by transforming growth factor beta: a proposed model for indirect mitogenesis involving autocrine activity.Chromatin binding of epidermal growth factor, nerve growth factor, and platelet-derived growth factor in cells bearing the appropriate surface receptors.Spontaneous expression of the c-sis gene and release of a platelet-derived growth factorlike molecule by human alveolar macrophages.Activation of coagulation releases endothelial cell mitogensType beta transforming growth factor in human platelets: release during platelet degranulation and action on vascular smooth muscle cells.An agent or agents produced by virus-transformed cells cause unregulated ruffling in untransformed cells.Distribution and modulation of the cellular receptor for transforming growth factor-betaTransforming growth factor-beta: possible roles in carcinogenesis.Repression of platelet-derived growth factor beta-receptor expression by mitogenic growth factors and transforming oncogenes in murine 3T3 fibroblasts.Platelet-rich plasma and platelet gel: a reviewRapid and selective alterations in the expression of cellular genes accompany conditional transcription of Ha-v-ras in NIH 3T3 cells.Increased secretion of type beta transforming growth factor accompanies viral transformation of cellsRegulation of the transcript for a lysosomal protein: evidence for a gene program modified by platelet-derived growth factorDifferential responsiveness of myc- and ras-transfected cells to growth factors: selective stimulation of myc-transfected cells by epidermal growth factorEfficient reversion of simian sarcoma virus-transformation and inhibition of growth factor-induced mitogenesis by suramin.Rat skeletal myoblasts and arterial smooth muscle cells express the gene for the A chain but not the gene for the B chain (c-sis) of platelet-derived growth factor (PDGF) and produce a PDGF-like protein.Production of platelet-derived growth factor-like molecules by cultured arterial smooth muscle cells accompanies proliferation after arterial injury.Anti-peptide antibodies detect oncogene-related proteins in urineArterial smooth muscle cells in primary culture produce a platelet-derived growth factor-like proteinExpression of the sis gene by endothelial cells in culture and in vivo.Blockade of autocrine stimulation in simian sarcoma virus-transformed cells reverses down-regulation of platelet-derived growth factor receptors.The platelet-derived growth factor alpha-receptor is encoded by a growth-arrest-specific (gas) gene.Type beta transforming growth factor: a bifunctional regulator of cellular growthSerum independence of transcription from the promoter of an avian retrovirus in v-src-transformed cells is a primary, intracellular effect of increased tyrosine phosphorylation.
P2860
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P2860
Production of platelet-derived growth factor-like molecules and reduced expression of platelet-derived growth factor receptors accompany transformation by a wide spectrum of agents
description
1984 nî lūn-bûn
@nan
1984年の論文
@ja
1984年学术文章
@wuu
1984年学术文章
@zh-cn
1984年学术文章
@zh-hans
1984年学术文章
@zh-my
1984年学术文章
@zh-sg
1984年學術文章
@yue
1984年學術文章
@zh
1984年學術文章
@zh-hant
name
Production of platelet-derived ...... n by a wide spectrum of agents
@ast
Production of platelet-derived ...... n by a wide spectrum of agents
@en
type
label
Production of platelet-derived ...... n by a wide spectrum of agents
@ast
Production of platelet-derived ...... n by a wide spectrum of agents
@en
prefLabel
Production of platelet-derived ...... n by a wide spectrum of agents
@ast
Production of platelet-derived ...... n by a wide spectrum of agents
@en
P2093
P2860
P356
P1476
Production of platelet-derived ...... n by a wide spectrum of agents
@en
P2093
P2860
P304
P356
10.1073/PNAS.81.8.2396
P407
P577
1984-04-01T00:00:00Z