Gene structure of CYP3A4, an adult-specific form of cytochrome P450 in human livers, and its transcriptional control.
about
The human orphan nuclear receptor PXR is activated by compounds that regulate CYP3A4 gene expression and cause drug interactionsFunctional analysis of basic transcription element (BTE)-binding protein (BTEB) 3 and BTEB4, a novel Sp1-like protein, reveals a subfamily of transcriptional repressors for the BTE site of the cytochrome P4501A1 gene promoterThe xenobiotic compound 1,4-bis[2-(3,5-dichloropyridyloxy)]benzene is an agonist ligand for the nuclear receptor CARThe gut-enriched Krüppel-like factor suppresses the activity of the CYP1A1 promoter in an Sp1-dependent fashionMolecular genetics of the human cytochrome P450 monooxygenase superfamilyCytochrome P450 CYP3A5 in the human anterior pituitary glandEvidence of impaired cisapride metabolism in neonatesA reporter gene assay to assess the molecular mechanisms of xenobiotic-dependent induction of the human CYP3A4 gene in vitroGenetic variability in CYP3A5 and its possible consequences.History of drug metabolism research in Japan.The human CYP3A subfamily: practical considerations.Pregnane X receptor and yin yang 1 contribute to the differential tissue expression and induction of CYP3A5 and CYP3A4.Cytochrome P450 single nucleotide polymorphisms in an indigenous Tanzanian population: a concern about the metabolism of artemisinin-based combinations.Receptor-dependent transcriptional activation of cytochrome P4503A genes: induction mechanisms, species differences and interindividual variation in man.Decision tree-based modeling of androgen pathway genes and prostate cancer riskIntrinsic sexually dimorphic expression of the principal human CYP3A4 correlated with suboptimal activation of GH/glucocorticoid-dependent transcriptional pathways in men.Polymorphisms and phenotypic analysis of cytochrome P450 3A4 in the Uygur population in northwest ChinaAssociation of CYP3A4 genotype with treatment-related leukemia.Cytochrome P450 3A4FNx011B as pharmacogenomic predictor of tacrolimus pharmacokinetics and clinical outcome in the liver transplant recipientsThe missing linkage: what pharmacogenetic associations are left to find in CYP3A?Transcriptional regulation and pharmacogenomics.Pharmacogenetics in solid organ transplantation: genes involved in mechanism of action and pharmacokinetics of immunosuppressive drugs.Regulation of human pregnane X receptor and its target gene cytochrome P450 3A4 by Chinese herbal compounds and a molecular docking study.Marmoset CYP3A21, a model for human CYP3A4: protein expression and functional characterization of the promoter.Transcriptional regulation of cytochrome P4503A4 gene expression: effects of inherited mutations in the 5'-flanking region.An in vitro bioassay for xenobiotics using the SXR-driven human CYP3A4/lacZ reporter gene.Molecular mechanisms of polymorphic CYP3A7 expression in adult human liver and intestine.CYP450 polymorphisms predict clinic outcomes to vinorelbine-based chemotherapy in patients with non-small-cell lung cancer.Differentiation of hepatocytes from induced pluripotent stem cells derived from human hair follicle mesenchymal stem cells.Determination of CYP3A4 Inducing Properties of Compounds Using a Laboratory-Developed Cell-Based Assay.Dynamics of Cytosine Methylation in the Proximal Promoters of CYP3A4 and CYP3A7 in Pediatric and Prenatal Livers.Bioprinting Perfusion-Enabled Liver Equivalents for Advanced Organ-on-a-Chip Applications.Systematic screening for polymorphisms in the CYP3A4 gene in the Chinese population.
P2860
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P2860
Gene structure of CYP3A4, an adult-specific form of cytochrome P450 in human livers, and its transcriptional control.
description
1993 nî lūn-bûn
@nan
1993 թուականի Դեկտեմբերին հրատարակուած գիտական յօդուած
@hyw
1993 թվականի դեկտեմբերին հրատարակված գիտական հոդված
@hy
1993年の論文
@ja
1993年論文
@yue
1993年論文
@zh-hant
1993年論文
@zh-hk
1993年論文
@zh-mo
1993年論文
@zh-tw
1993年论文
@wuu
name
Gene structure of CYP3A4, an a ...... d its transcriptional control.
@ast
Gene structure of CYP3A4, an a ...... d its transcriptional control.
@en
Gene structure of CYP3A4, an a ...... d its transcriptional control.
@nl
type
label
Gene structure of CYP3A4, an a ...... d its transcriptional control.
@ast
Gene structure of CYP3A4, an a ...... d its transcriptional control.
@en
Gene structure of CYP3A4, an a ...... d its transcriptional control.
@nl
prefLabel
Gene structure of CYP3A4, an a ...... d its transcriptional control.
@ast
Gene structure of CYP3A4, an a ...... d its transcriptional control.
@en
Gene structure of CYP3A4, an a ...... d its transcriptional control.
@nl
P2093
P2860
P1433
P1476
Gene structure of CYP3A4, an a ...... nd its transcriptional control
@en
P2093
P2860
P304
P356
10.1111/J.1432-1033.1993.TB18412.X
P407
P50
P577
1993-12-01T00:00:00Z