Pregnenolone 16 alpha-carbonitrile-inducible P-450 gene family: gene conversion and differential regulation
about
SXR, a novel steroid and xenobiotic-sensing nuclear receptorThe rat P450 IID subfamily: complete sequences of four closely linked genes and evidence that gene conversions maintained sequence homogeneity at the heme-binding region of the cytochrome P450 active siteProfile of territrem metabolism and cytochrome P-450 3A expression in liver microsomes from Wistar rats of both genders as a function of ageCloning, experession and chromosomal localization of a member of the human cytochrome P450IIC gene sub-familyIsolation and sequence of cDNA encoding a cytochrome P-450 from an insecticide-resistant strain of the house fly, Musca domestica.Genetic and epigenetic regulation and expression signatures of glutathione S-transferases in developing mouse liver.Gene structure of CYP3A4, an adult-specific form of cytochrome P450 in human livers, and its transcriptional control.Erythromycin breath test as an assay of glucocorticoid-inducible liver cytochromes P-450. Studies in rats and patients.Receptor-dependent transcriptional activation of cytochrome P4503A genes: induction mechanisms, species differences and interindividual variation in man.The gene CYP3 encoding P450pcn1 (nifedipine oxidase) is tightly linked to the gene COL1A2 encoding collagen type 1 alpha on 7q21-q22.1.Identification of glucocorticoid-inducible cytochromes P-450 in the intestinal mucosa of rats and manIntrinsic sexually dimorphic expression of the principal human CYP3A4 correlated with suboptimal activation of GH/glucocorticoid-dependent transcriptional pathways in men.Induction of the Cyp1a-1 dioxin-responsive enhancer in transgenic mice.Glucocorticoid regulation of a phenobarbital-inducible cytochrome P-450 gene: the presence of a functional glucocorticoid response element in the 5'-flanking region of the CYP2B2 gene.Phenobarbital induction of cytochrome P-450 gene expression.Cytochromes P-450 in rats: structures, functions, properties and relevant human forms.The human hepatic cytochromes P450 involved in drug metabolism.Inherent sex-dependent regulation of human hepatic CYP3A5Role of the liver-enriched transcription factor DBP in expression of the cytochrome P450 CYP2C6 geneRETRACTED: CYP2D6 Is Inducible by Endogenous and Exogenous CorticosteroidsParadoxical transcriptional activation of rat liver cytochrome P-450 3A1 by dexamethasone and the antiglucocorticoid pregnenolone 16 alpha-carbonitrile: analysis by transient transfection into primary monolayer cultures of adult rat hepatocytes.Evidence from dwarf rats that growth hormone may not regulate the sexual differentiation of liver cytochrome P450 enzymes and steroid 5 alpha-reductase.Impact of rat P450 genetic polymorphism on diazepam metabolism.Dexamethasone responsiveness of a major glucocorticoid-inducible CYP3A gene is mediated by elements unrelated to a glucocorticoid receptor binding motif.Effect of prototypical inducers on ligand activated nuclear receptor regulated drug disposition genes in rodent hepatic and intestinal cells.Risk assessment for aflatoxin: I. Metabolism of aflatoxin B1 by different species.Two CCAAT/enhancer binding protein sites in the cytochrome P4503A1 locus. Potential role in the glucocorticoid response.Differential regulation of the cytochrome P450 3A1 gene transcription by dexamethasone in immature and adult rat liver.Acetaminophen induces accumulation of functional rat CYP3A via polyubiquitination dysfunction.Degradation of rat hepatic cytochrome P-450p.Developmental aspects of P450IIIA: prenatal activity and inducibility.Effect of Tissue-Culture Substratum and Extracellular Matrix Overlay on Liver-Selective and Xenobiotic Inducible Gene Expression in Primary Rat Hepatocytes.Induction of cytochrome P-450 in the Norway rat, Rattus norvegicus, following exposure to potential environmental contaminants.Absorption, distribution, metabolism and elimination of 14C-ETX0914, a novel inhibitor of bacterial type-II topoisomerases in rodents.Monoclonal antibodies against human cytochrome P-450 recognizing different pregnenolone 16 alpha-carbonitrile-inducible rat cytochromes P-450Purification and characterization of an anticonvulsant-induced human cytochrome P-450 catalysing cyclosporin metabolism.Induction of cytochrome P450III and P450IV family proteins in streptozotocin-induced diabetes.Immunochemical evidence for multiple steroid-inducible hepatic cytochromes P-450 in the rat.Differences in adult and foetal human cytochrome P-450 forms recognized by monoclonal antibodies with specificity for the P450III family.Increase in a specific cytochrome P-450 isoenzyme in the liver of congenitally jaundiced Gunn rats.
P2860
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P2860
Pregnenolone 16 alpha-carbonitrile-inducible P-450 gene family: gene conversion and differential regulation
description
1986 nî lūn-bûn
@nan
1986年の論文
@ja
1986年学术文章
@wuu
1986年学术文章
@zh-cn
1986年学术文章
@zh-hans
1986年学术文章
@zh-my
1986年学术文章
@zh-sg
1986年學術文章
@yue
1986年學術文章
@zh
1986年學術文章
@zh-hant
name
Pregnenolone 16 alpha-carbonit ...... on and differential regulation
@ast
Pregnenolone 16 alpha-carbonit ...... on and differential regulation
@en
type
label
Pregnenolone 16 alpha-carbonit ...... on and differential regulation
@ast
Pregnenolone 16 alpha-carbonit ...... on and differential regulation
@en
prefLabel
Pregnenolone 16 alpha-carbonit ...... on and differential regulation
@ast
Pregnenolone 16 alpha-carbonit ...... on and differential regulation
@en
P2093
P2860
P356
P1476
Pregnenolone 16 alpha-carbonit ...... on and differential regulation
@en
P2093
P2860
P304
P356
10.1128/MCB.6.8.2969
P407
P577
1986-08-01T00:00:00Z