Inhibition of microglial P2X4 receptors attenuates morphine tolerance, Iba1, GFAP and mu opioid receptor protein expression while enhancing perivascular microglial ED2.
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Pain and Poppies: The Good, the Bad, and the Ugly of Opioid AnalgesicsOpioid-induced central immune signaling: implications for opioid analgesiaGlial modulators as potential treatments of psychostimulant abuseToll-like receptor 4 mutant and null mice retain morphine-induced tolerance, hyperalgesia, and physical dependence.P2X4 Receptor Function in the Nervous System and Current Breakthroughs in Pharmacology.Morphine tolerance attenuates the resolution of postoperative pain and enhances spinal microglial p38 and extracellular receptor kinase phosphorylation.Delta-opioid receptor analgesia is independent of microglial activation in a rat model of neuropathic painNADPH-oxidase 2 activation promotes opioid-induced antinociceptive tolerance in mice.Exploring the neuroimmunopharmacology of opioids: an integrative review of mechanisms of central immune signaling and their implications for opioid analgesia.Microglia: a promising target for treating neuropathic and postoperative pain, and morphine toleranceToll-like receptors in chronic pain.Procyanidins alleviates morphine tolerance by inhibiting activation of NLRP3 inflammasome in microgliaAntinociceptive Interactions between the Imidazoline I2 Receptor Agonist 2-BFI and Opioids in Rats: Role of Efficacy at the μ-Opioid Receptor.BK channels in microglia are required for morphine-induced hyperalgesia.Morphine hyperalgesia gated through microglia-mediated disruption of neuronal Cl⁻ homeostasis.Glial responses after chorda tympani nerve injury.Regulation of morphine-induced synaptic alterations: Role of oxidative stress, ER stress, and autophagy.Allostatic Mechanisms of Opioid Tolerance Beyond Desensitization and DownregulationLoss of μ opioid receptor signaling in nociceptors, but not microglia, abrogates morphine tolerance without disrupting analgesia.Ligand-gated purinergic receptors regulate HIV-1 Tat and morphine related neurotoxicity in primary mouse striatal neuron-glia co-cultures.Exploring neuroinflammation as a potential avenue to improve the clinical efficacy of opioids.Opioid and chemokine receptor crosstalk: a promising target for pain therapy?Targeting AMPK for the Alleviation of Pathological Pain.Resveratrol reduces morphine tolerance by inhibiting microglial activation via AMPK signalling.Purinergic signaling in microglia in the pathogenesis of neuropathic pain.TNP-ATP is Beneficial for Treatment of Neonatal Hypoxia-Induced Hypomyelination and Cognitive Decline.Complement factor C5a and C5a receptor contribute to morphine tolerance and withdrawal-induced hyperalgesia in ratsTargeting microglial purinergic signaling to improve morphine analgesia.Distinct migratory behaviors of striosome and matrix cells underlying the mosaic formation in the developing striatum.Absence of μ opioid receptor mRNA expression in astrocytes and microglia of rat spinal cordMicroglial activation involved in morphine tolerance is not mediated by toll-like receptor 4.Satureja khuzestanica prevents the development of morphine analgesic tolerance through suppression of spinal glial cell activation in rats.The imidazoline I2 receptor agonist 2-BFI attenuates hypersensitivity and spinal neuroinflammation in a rat model of neuropathic pain.Yokukansan, a Kampo medicine, prevents the development of morphine tolerance through the inhibition of spinal glial cell activation in rats.A Pharmacological Rationale to Reduce the Incidence of Opioid Induced Tolerance and Hyperalgesia: A Review.The Regulatory Mechanisms and Therapeutic Potential of MicroRNAs: From Chronic Pain to Morphine Tolerance.Yokukansan (Kampo medicinal formula) prevents the development of morphine tolerance by inhibiting the secretion of orexin A.
P2860
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P2860
Inhibition of microglial P2X4 receptors attenuates morphine tolerance, Iba1, GFAP and mu opioid receptor protein expression while enhancing perivascular microglial ED2.
description
2010 nî lūn-bûn
@nan
2010 թուականի Յունիսին հրատարակուած գիտական յօդուած
@hyw
2010 թվականի հունիսին հրատարակված գիտական հոդված
@hy
2010年の論文
@ja
2010年論文
@yue
2010年論文
@zh-hant
2010年論文
@zh-hk
2010年論文
@zh-mo
2010年論文
@zh-tw
2010年论文
@wuu
name
Inhibition of microglial P2X4 ...... g perivascular microglial ED2.
@ast
Inhibition of microglial P2X4 ...... g perivascular microglial ED2.
@en
Inhibition of microglial P2X4 ...... g perivascular microglial ED2.
@nl
type
label
Inhibition of microglial P2X4 ...... g perivascular microglial ED2.
@ast
Inhibition of microglial P2X4 ...... g perivascular microglial ED2.
@en
Inhibition of microglial P2X4 ...... g perivascular microglial ED2.
@nl
prefLabel
Inhibition of microglial P2X4 ...... g perivascular microglial ED2.
@ast
Inhibition of microglial P2X4 ...... g perivascular microglial ED2.
@en
Inhibition of microglial P2X4 ...... g perivascular microglial ED2.
@nl
P2093
P2860
P1433
P1476
Inhibition of microglial P2X4 ...... g perivascular microglial ED2.
@en
P2093
E Alfonso Romero-Sandoval
Joyce A De Leo
Ryan J Horvath
P2860
P304
P356
10.1016/J.PAIN.2010.02.042
P407
P577
2010-06-22T00:00:00Z