Targeted disruption of the M(r) 46,000 mannose 6-phosphate receptor gene in mice results in misrouting of lysosomal proteins

Targeted disruption of the M(r) 46,000 mannose 6-phosphate receptor gene in mice results in misrouting of lysosomal proteins

Item
http://www.wikidata.org/entity/Q34065410
Mice deficient for the lysosomal proteinase cathepsin D exhibit progressive atrophy of the intestinal mucosa and profound destruction of lymphoid cellsRole of LAMP-2 in lysosome biogenesis and autophagyThe trans-Golgi network accessory protein p56 promotes long-range movement of GGA/clathrin-containing transport carriers and lysosomal enzyme sorting.mu1A-adaptin-deficient mice: lethality, loss of AP-1 binding and rerouting of mannose 6-phosphate receptorsPhenotype of arylsulfatase A-deficient mice: relationship to human metachromatic leukodystrophyDeletion of the SNARE vti1b in mice results in the loss of a single SNARE partner, syntaxin 8.Class IA phosphatidylinositol 3-kinase p110α regulates phagosome maturation.Glucosidase II and MRH-domain containing proteins in the secretory pathway.Tissue-specific inactivation of murine M6P/IGF2R.SCYL2 Protects CA3 Pyramidal Neurons from Excitotoxicity during Functional Maturation of the Mouse Hippocampus.Impaired osteoclastic bone resorption leads to osteopetrosis in cathepsin-K-deficient miceTargeted disruption of the arylsulfatase B gene results in mice resembling the phenotype of mucopolysaccharidosis VIDifferential sorting of lysosomal enzymes in mannose 6-phosphate receptor-deficient fibroblasts.Role of cathepsin B in intracellular trypsinogen activation and the onset of acute pancreatitis.Neither type of mannose 6-phosphate receptor is sufficient for targeting of lysosomal enzymes along intracellular routes.Mouse mutants lacking the cation-independent mannose 6-phosphate/insulin-like growth factor II receptor are impaired in lysosomal enzyme transport: comparison of cation-independent and cation-dependent mannose 6-phosphate receptor-deficient mice.
P2860

Targeted disruption of the M(r) 46,000 mannose 6-phosphate receptor gene in mice results in misrouting of lysosomal proteins

Item
http://www.wikidata.org/entity/Q34065410
description
1993 nî lūn-bûn
@nan
1993 թուականի Դեկտեմբերին հրատարակուած գիտական յօդուած
@hyw
1993 թվականի դեկտեմբերին հրատարակված գիտական հոդված
@hy
1993年の論文
@ja
1993年論文
@yue
1993年論文
@zh-hant
1993年論文
@zh-hk
1993年論文
@zh-mo
1993年論文
@zh-tw
1993年论文
@wuu
name
Targeted disruption of the M(r ...... srouting of lysosomal proteins
@ast
Targeted disruption of the M(r ...... srouting of lysosomal proteins
@en
Targeted disruption of the M(r ...... srouting of lysosomal proteins
@nl
type
label
Targeted disruption of the M(r ...... srouting of lysosomal proteins
@ast
Targeted disruption of the M(r ...... srouting of lysosomal proteins
@en
Targeted disruption of the M(r ...... srouting of lysosomal proteins
@nl
prefLabel
Targeted disruption of the M(r ...... srouting of lysosomal proteins
@ast
Targeted disruption of the M(r ...... srouting of lysosomal proteins
@en
Targeted disruption of the M(r ...... srouting of lysosomal proteins
@nl
P1433
P1476
P2093
P2860
P304
P31
P356
P407
P433
P478
P577
P698
P932
P356
P1433
P1476
Targeted disruption of the M(r ...... srouting of lysosomal proteins
@en
P2093
P2860
P304
P31
P356
10.1002/J.1460-2075.1993.TB06217.X
P407
P433
P478
P577
P698
P932