Position-effect protection and enhancer blocking by the chicken beta-globin insulator are separable activities. - Wikidata - awgldk - TriplyDB

Position-effect protection and enhancer blocking by the chicken beta-globin insulator are separable activities.

Position-effect protection and enhancer blocking by the chicken beta-globin insulator are separable activities.

http://www.wikidata.org/entity/Q34067751

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Heterogeneous nuclear ribonucleoprotein C1/C2, MeCP1, and SWI/SNF form a chromatin remodeling complex at the beta-globin locus control region The insulation of genes from external enhancers and silencing chromatin.CTCF: master weaver of the genome Global analysis of the insulator binding protein CTCF in chromatin barrier regions reveals demarcation of active and repressive domains Locus control regions Cloning and characterization of cDNAs encoding putative CTCFs in the mosquitoes, Aedes aegypti and Anopheles gambiae Current and future alternative therapies for beta-thalassemia major The complex transcription regulatory landscape of our genome: control in three dimensions CTCF: the protein, the binding partners, the binding sites and their chromatin loops Insulators: exploiting transcriptional and epigenetic mechanisms Epigenetic boundaries of tumour suppressor gene promoters: the CTCF connection and its role in carcinogenesis CTCF mediates long-range chromatin looping and local histone modification in the beta-globin locus Shielding of sleeping beauty DNA transposon-delivered transgene cassettes by heterologous insulators in early embryonal cells Evx2-Hoxd13 intergenic region restricts enhancer association to Hoxd13 promoter.CTCF genomic binding sites in Drosophila and the organisation of the bithorax complex Analysis of chromatin boundary activity in Drosophila cells.The D4Z4 macrosatellite repeat acts as a CTCF and A-type lamins-dependent insulator in facio-scapulo-humeral dystrophy.In vivo expression of MHC class I genes depends on the presence of a downstream barrier element The 3' region of the chicken hypersensitive site-4 insulator has properties similar to its core and is required for full insulator activity.VEZF1 elements mediate protection from DNA methylation.Modular insulators: genome wide search for composite CTCF/thyroid hormone receptor binding sites Visualizing the distribution of synapses from individual neurons in the mouse brain.Complete biallelic insulation at the H19/Igf2 imprinting control region position results in fetal growth retardation and perinatal lethality A functional screen for regulatory elements that improve retroviral vector gene expression Evaluation of combinatorial cis-regulatory elements for stable gene expression in chicken cells.Genotoxic potential of lineage-specific lentivirus vectors carrying the beta-globin locus control region.Genomic and functional assays demonstrate reduced gammaretroviral vector genotoxicity associated with use of the cHS4 chromatin insulator.Optimized lentiviral vector design improves titer and transgene expression of vectors containing the chicken beta-globin locus HS4 insulator element.Recombinant human plasma phospholipid transfer protein (PLTP) to prevent bacterial growth and to treat sepsis.Mobilization and mechanism of transcription of integrated self-inactivating lentiviral vectors.BAC TG-EMBED: one-step method for high-level, copy-number-dependent, position-independent transgene expression.A gene-rich, transcriptionally active environment and the pre-deposition of repressive marks are predictive of susceptibility to KRAB/KAP1-mediated silencing.Histone crosstalk directed by H2B ubiquitination is required for chromatin boundary integrity CTCF shapes chromatin by multiple mechanisms: the impact of 20 years of CTCF research on understanding the workings of chromatin.Human C-reactive protein does not promote atherosclerosis in transgenic rabbits.Live imaging of apoptosis in a novel transgenic mouse highlights its role in neural tube closure.Lineage- and stage-restricted lentiviral vectors for the gene therapy of chronic granulomatous disease.USF binding sequences from the HS4 insulator element impose early replication timing on a vertebrate replicator.Mammalian linker-histone subtypes differentially affect gene expression in vivo Gene therapy for hemoglobinopathies: the state of the field and the future.

P2860

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P2860

Position-effect protection and enhancer blocking by the chicken beta-globin insulator are separable activities.

http://www.wikidata.org/entity/Q34067751

description

2002 nî lūn-bûn

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2002 թուականի Մայիսին հրատարակուած գիտական յօդուած

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2002 թվականի մայիսին հրատարակված գիտական հոդված

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2002年の論文

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2002年論文

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2002年論文

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2002年論文

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Position-effect protection and ...... ator are separable activities.

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Position-effect protection and ...... ator are separable activities.

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Position-effect protection and ...... ator are separable activities.

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type

label

Position-effect protection and ...... ator are separable activities.

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Position-effect protection and ...... ator are separable activities.

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Position-effect protection and ...... ator are separable activities.

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Position-effect protection and ...... ator are separable activities.

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Position-effect protection and ...... ator are separable activities.

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Position-effect protection and ...... ator are separable activities.

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Proceedings of the National Academy of Sciences of the United States of America

P1476

Position-effect protection and ...... ator are separable activities.

@en

P2093

Adam C Bell

http://www.w3.org/2001/XMLSchema#string

Adam G West

http://www.w3.org/2001/XMLSchema#string

Bonnie Burgess-Beusse

http://www.w3.org/2001/XMLSchema#string

Félix Recillas-Targa

http://www.w3.org/2001/XMLSchema#string

Gary Felsenfeld

http://www.w3.org/2001/XMLSchema#string

Michael D Litt

http://www.w3.org/2001/XMLSchema#string

Michael J Pikaart

http://www.w3.org/2001/XMLSchema#string

Miklos Gaszner

http://www.w3.org/2001/XMLSchema#string

P2860

Transcriptional repression by the insulator protein CTCF involves histone deacetylases

The protein CTCF is required for the enhancer blocking activity of vertebrate insulators

Methylation of a CTCF-dependent boundary controls imprinted expression of the Igf2 gene

CTCF mediates methylation-sensitive enhancer-blocking activity at the H19/Igf2 locus

Transitions in histone acetylation reveal boundaries of three separately regulated neighboring loci

Mutational analysis of the chicken beta-globin enhancer reveals two positive-acting domains

The establishment of active chromatin domains.

An insulator element and condensed chromatin region separate the chicken beta-globin locus from an independently regulated erythroid-specific folate receptor gene

Insulators and boundaries: versatile regulatory elements in the eukaryotic genome.

A 5' element of the chicken beta-globin domain serves as an insulator in human erythroid cells and protects against position effect in Drosophila.

P304

6883-6888

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scholarly article

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10.1073/PNAS.102179399

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10

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99

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2002-05-01T00:00:00Z

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P5875

11360941

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P698

12011446

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P932

124498

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