Mutational analysis of the chicken beta-globin enhancer reveals two positive-acting domains
about
HMG I/Y regulates long-range enhancer-dependent transcription on DNA and chromatin by changes in DNA topologyPurification of the human NF-E2 complex: cDNA cloning of the hematopoietic cell-specific subunit and evidence for an associated partnerSmall Maf proteins interact with the human transcription factor TCF11/Nrf1/LCR-F1DNA-binding specificities of the GATA transcription factor familyA novel, erythroid cell-specific murine transcription factor that binds to the CACCC element and is related to the Krüppel family of nuclear proteinsPerinatal synthetic lethality and hematopoietic defects in compound mafG::mafK mutant miceZinc fingers 1-7 of EVI1 fail to bind to the GATA motif by itself but require the core site GACAAGATA for bindingCis- and trans-acting elements involved in the regulation of the erythroid promoter of the human porphobilinogen deaminase geneOne enhancer mediates mafK transcriptional activation in both hematopoietic and cardiac muscle cells.Detailed analysis of the site 3 region of the human beta-globin dominant control regionIdentification of a stage selector element in the human gamma-globin gene promoter that fosters preferential interaction with the 5' HS2 enhancer when in competition with the beta-promoter.Position-effect protection and enhancer blocking by the chicken beta-globin insulator are separable activities.Localization and characterization of the DNase I-hypersensitive site II (HS II) enhancer. A critical regulatory element within the beta-globin locus-activating region.Transcriptional control of erythropoiesis: emerging mechanisms and principles.Loss of transcriptional activity of a transgene is accompanied by DNA methylation and histone deacetylation and is prevented by insulators.The barrier function of an insulator couples high histone acetylation levels with specific protection of promoter DNA from methylation.Two tissue-specific factors bind the erythroid promoter of the human porphobilinogen deaminase geneStructure and function of the enhancer 3' to the human A gamma globin geneAnalysis of erythroid nuclear proteins binding to the promoter and enhancer elements of the chicken histone H5 geneA small single-"finger" peptide from the erythroid transcription factor GATA-1 binds specifically to DNA as a zinc or iron complexHomotypic interactions of chicken GATA-1 can mediate transcriptional activationEssential role of NF-E2 in remodeling of chromatin structure and transcriptional activation of the epsilon-globin gene in vivo by 5' hypersensitive site 2 of the beta-globin locus control regionDistal enhancer regulation by promoter derepression in topologically constrained DNA in vitro.Enhancer-dependent transcription of the epsilon-globin promoter requires promoter-bound GATA-1 and enhancer-bound AP-1/NF-E2trans-Activation of a globin promoter in nonerythroid cells.Cloning and characterization of a novel erythroid cell-derived CNC family transcription factor heterodimerizing with the small Maf family proteinsTranscriptional role of a conserved GATA-1 site in the human epsilon-globin gene promoterTranscription of the histone H5 gene is regulated by three differentiation-specific enhancers.Activity and expression of murine small Maf family protein MafK.Developmental regulation of topoisomerase II sites and DNase I-hypersensitive sites in the chicken beta-globin locus.Synergy between the NF-E1 erythroid-specific transcription factor and the CACCC factor in the erythroid-specific promoter of the human porphobilinogen deaminase genePromoter elements and erythroid cell nuclear factors that regulate alpha-globin gene transcription in vitro.Positional enhancer-blocking activity of the chicken beta-globin insulator in transiently transfected cells.Purification and characterization of an erythroid cell-specific factor that binds the murine alpha- and beta-globin genes.An internal regulatory element controls troponin I gene expression.Identification and characterization of a chicken alpha-globin enhancer.Regulated expression of globin chains and the erythroid transcription factor GATA-1 during erythropoiesis in the developing mouse.The intragenic enhancer of human immunodeficiency virus type 1 contains functional AP-1 binding sites.Epigenetics of beta-globin gene regulationStructure and promoter activity of the gene for the erythroid transcription factor GATA-1.
P2860
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P2860
Mutational analysis of the chicken beta-globin enhancer reveals two positive-acting domains
description
1988 nî lūn-bûn
@nan
1988 թուականի Սեպտեմբերին հրատարակուած գիտական յօդուած
@hyw
1988 թվականի սեպտեմբերին հրատարակված գիտական հոդված
@hy
1988年の論文
@ja
1988年論文
@yue
1988年論文
@zh-hant
1988年論文
@zh-hk
1988年論文
@zh-mo
1988年論文
@zh-tw
1988年论文
@wuu
name
Mutational analysis of the chi ...... ls two positive-acting domains
@ast
Mutational analysis of the chi ...... ls two positive-acting domains
@en
type
label
Mutational analysis of the chi ...... ls two positive-acting domains
@ast
Mutational analysis of the chi ...... ls two positive-acting domains
@en
prefLabel
Mutational analysis of the chi ...... ls two positive-acting domains
@ast
Mutational analysis of the chi ...... ls two positive-acting domains
@en
P2860
P356
P1476
Mutational analysis of the chi ...... ls two positive-acting domains
@en
P2093
Felsenfeld G
P2860
P304
P356
10.1073/PNAS.85.17.6267
P407
P577
1988-09-01T00:00:00Z