Regulator of G protein signaling 5 protects against cardiac hypertrophy and fibrosis during biomechanical stress of pressure overload - Wikidata - awgldk - TriplyDB

Regulator of G protein signaling 5 protects against cardiac hypertrophy and fibrosis during biomechanical stress of pressure overload

Regulator of G protein signaling 5 protects against cardiac hypertrophy and fibrosis during biomechanical stress of pressure overload

http://www.wikidata.org/entity/Q34068533

about

Gq/11-mediated signaling and hypertrophy in mice with cardiac-specific transgenic expression of regulator of G-protein signaling 2 Extracellular signal-regulated kinases 1/2 as regulators of cardiac hypertrophy Fibroblast growth factor receptor 1 signaling in adult cardiomyocytes increases contractility and results in a hypertrophic cardiomyopathy Regulators of G-protein signaling in the heart and their potential as therapeutic targets.Activating transcription factor 3 deficiency promotes cardiac hypertrophy, dysfunction, and fibrosis induced by pressure overload PDGF-dependent regulation of regulator of G protein signaling-5 expression and vascular smooth muscle cell functionality.Regulator of G-protein signaling-5 inhibits bronchial smooth muscle contraction in severe asthma.Loss of MD1 exacerbates pressure overload-induced left ventricular structural and electrical remodelling.Loss of regulator of G protein signaling 5 exacerbates obesity, hepatic steatosis, inflammation and insulin resistance.Augmented cardiac hypertrophy in response to pressure overload in mice lacking ELTD1.3,3'-Diindolylmethane protects against cardiac hypertrophy via 5'-adenosine monophosphate-activated protein kinase-α2 IKKi deficiency promotes pressure overload-induced cardiac hypertrophy and fibrosis.Beta-agonist-associated reduction in RGS5 expression promotes airway smooth muscle hyper-responsiveness.Interferon regulatory factor 7 protects against vascular smooth muscle cell proliferation and neointima formation.Never in mitosis gene A related kinase-6 attenuates pressure overload-induced activation of the protein kinase B pathway and cardiac hypertrophy MicroRNAs that target RGS5.Regulator of G-protein signaling-5 is a marker of hepatic stellate cells and expression mediates response to liver injury Signal regulatory protein-α protects against cardiac hypertrophy via the disruption of toll-like receptor 4 signaling Alk7 Depleted Mice Exhibit Prolonged Cardiac Repolarization and Are Predisposed to Ventricular Arrhythmia.Regulator of G-protein signalling 5 protects against atherosclerosis in apolipoprotein E-deficient mice.The interferon regulatory factors as novel potential targets in the treatment of cardiovascular diseases.Atrial tachyarrhythmia in Rgs5-null mice.IRAK4 deficiency promotes cardiac remodeling induced by pressure overload.Angiotensin-Converting Enzyme 3 (ACE3) Protects Against Pressure Overload-Induced Cardiac Hypertrophy.Pioglitazone Protected against Cardiac Hypertrophy via Inhibiting AKT/GSK3β and MAPK Signaling Pathways.Tripartite motif 32 prevents pathological cardiac hypertrophy The ubiquitin E3 ligase TRAF6 exacerbates pathological cardiac hypertrophy via TAK1-dependent signalling.Regulator of G protein signalling 14 attenuates cardiac remodelling through the MEK-ERK1/2 signalling pathway.Role of interferon regulatory factor 4 in the regulation of pathological cardiac hypertrophy Disruption of mindin exacerbates cardiac hypertrophy and fibrosis.Potential Role of Regulator of G-Protein Signaling 5 in the Protection of Vagal-Related Bradycardia and Atrial Tachyarrhythmia.Interferon regulatory factor 8 modulates phenotypic switching of smooth muscle cells by regulating the activity of myocardin.IRF8 suppresses pathological cardiac remodelling by inhibiting calcineurin signalling.Novel Protective Role of Myeloid Differentiation 1 in Pathological Cardiac Remodelling Toll-interacting protein (Tollip) negatively regulates pressure overload-induced ventricular hypertrophy in mice Interferon regulatory factor 7 functions as a novel negative regulator of pathological cardiac hypertrophy G protein-dependent and G protein-independent signaling pathways and their impact on cardiac function.Hypoxia activates muscle-restricted coiled-coil protein (MURC) expression via transforming growth factor-β in cardiac myocytes.Interferon regulatory factor 7 deficiency prevents diet-induced obesity and insulin resistance.Vinexin-β protects against cardiac hypertrophy by blocking the Akt-dependent signalling pathway.

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Regulator of G protein signaling 5 protects against cardiac hypertrophy and fibrosis during biomechanical stress of pressure overload

http://www.wikidata.org/entity/Q34068533

description

2010 nî lūn-bûn

@nan

2010 թուականի Յուլիսին հրատարակուած գիտական յօդուած

@hyw

2010 թվականի հուլիսին հրատարակված գիտական հոդված

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2010年の論文

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2010年論文

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2010年論文

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2010年論文

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2010年論文

@zh-mo

2010年論文

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2010年论文

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name

Regulator of G protein signali ...... al stress of pressure overload

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Regulator of G protein signali ...... al stress of pressure overload

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Regulator of G protein signali ...... al stress of pressure overload

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Regulator of G protein signali ...... al stress of pressure overload

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PNAS.1008397107

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Proceedings of the National Academy of Sciences of the United States of America

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Regulator of G protein signali ...... al stress of pressure overload

@en

P2093

Chengwei He

http://www.w3.org/2001/XMLSchema#string

Congxin Huang

http://www.w3.org/2001/XMLSchema#string

He Huang

http://www.w3.org/2001/XMLSchema#string

Heng Zhou

http://www.w3.org/2001/XMLSchema#string

Hong Jiang

http://www.w3.org/2001/XMLSchema#string

Hongliang Li

http://www.w3.org/2001/XMLSchema#string

Jinhua Feng

http://www.w3.org/2001/XMLSchema#string

Mu Qin

http://www.w3.org/2001/XMLSchema#string

Peter P Liu

http://www.w3.org/2001/XMLSchema#string

Qizhu Tang

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P2860

LIM and cysteine-rich domains 1 regulates cardiac hypertrophy by targeting calcineurin/nuclear factor of activated T cells signaling

Targeted cardiac overexpression of A20 improves left ventricular performance and reduces compensatory hypertrophy after myocardial infarction

Targeted expression of receptor-associated late transducer inhibits maladaptive hypertrophy via blocking epidermal growth factor receptor signaling

Cytoplasmic signaling pathways that regulate cardiac hypertrophy.

Involvement of extracellular signal-regulated kinases 1/2 in cardiac hypertrophy and cell death.

A mechanistic role for cardiac myocyte apoptosis in heart failure.

Calcineurin-NFAT signaling regulates the cardiac hypertrophic response in coordination with the MAPKs.

Mediating ERK 1/2 signaling rescues congenital heart defects in a mouse model of Noonan syndrome.

Generation and characterization of rgs5 mutant mice.

Rgs5 targeting leads to chronic low blood pressure and a lean body habitus.

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13818-13823

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scholarly article

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10.1073/PNAS.1008397107

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31

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107

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2010-07-19T00:00:00Z

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45275104

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20643937

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2922261

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