Inhibition of prolyl hydroxylases by dimethyloxaloylglycine after stroke reduces ischemic brain injury and requires hypoxia inducible factor-1α. - Wikidata - awgldk - TriplyDB

Inhibition of prolyl hydroxylases by dimethyloxaloylglycine after stroke reduces ischemic brain injury and requires hypoxia inducible factor-1α.

Inhibition of prolyl hydroxylases by dimethyloxaloylglycine after stroke reduces ischemic brain injury and requires hypoxia inducible factor-1α.

http://www.wikidata.org/entity/Q34068989

about

Cell based therapies for ischemic stroke: from basic science to bedside Mobilization of endogenous bone marrow derived endothelial progenitor cells and therapeutic potential of parathyroid hormone after ischemic stroke in mice Creatine kinase in ischemic and inflammatory disorders Molecular mechanisms of ischemic preconditioning in the kidney Molecular mechanisms of action and therapeutic uses of pharmacological inhibitors of HIF-prolyl 4-hydroxylases for treatment of ischemic diseases Activity-dependent silencing reveals functionally distinct itch-generating sensory neurons.HIF-1α activation results in actin cytoskeleton reorganization and modulation of Rac-1 signaling in endothelial cells Relative Contribution of Prolyl Hydroxylase-Dependent and -Independent Degradation of HIF-1alpha by Proteasomal Pathways in Cerebral Ischemia.Cell type-specific dependency on the PI3K/Akt signaling pathway for the endogenous Epo and VEGF induction by baicalein in neurons versus astrocytes.Hypoxia inducible factor-1alpha mediates protection of DL-3-n-butylphthalide in brain microvascular endothelial cells against oxygen glucose deprivation-induced injury.Preconditioning of bone marrow mesenchymal stem cells by prolyl hydroxylase inhibition enhances cell survival and angiogenesis in vitro and after transplantation into the ischemic heart of rats Preischemic targeting of HIF prolyl hydroxylation inhibits fibrosis associated with acute kidney injury A novel stroke therapy of pharmacologically induced hypothermia after focal cerebral ischemia in mice.Hypoxia-inducible factor prolyl hydroxylase inhibition: robust new target or another big bust for stroke therapeutics?Neurodevelopmental implications of the general anesthesia in neonate and infants.Method parameters' impact on mortality and variability in mouse stroke experiments: a meta-analysis.Citalopram enhances neurovascular regeneration and sensorimotor functional recovery after ischemic stroke in mice.Hypoxia-inducible factor 1 contributes to N-acetylcysteine's protection in stroke.Pleiotropic effects of dronedarone on ischemia/reperfusion injury in heart and brain.Hypoxia-inducible factor prolyl hydroxylases as targets for neuroprotection by "antioxidant" metal chelators: From ferroptosis to stroke.Prolyl 4-hydroxylases, master regulators of the hypoxia response.Hypoxia-inducible factor signalling mechanisms in the central nervous system.Preconditioning strategy in stem cell transplantation therapy.Endogenous recovery after brain damage: molecular mechanisms that balance neuronal life/death fate.Inhibition of Prolyl Hydroxylase Attenuates Fas Ligand-Induced Apoptosis and Lung Injury in Mice.Hypoxia-inducible factors as neuroprotective agent in Alzheimer's disease.Neuroprotective and regenerative roles of intranasal Wnt-3a Administration after focal ischemic stroke in mice.HIF prolyl hydroxylase inhibition prior to transient focal cerebral ischaemia is neuroprotective in mice.Optogenetic stimulation of glutamatergic neuronal activity in the striatum enhances neurogenesis in the subventricular zone of normal and stroke mice.The prolyl 4-hydroxylase inhibitor GSK360A decreases post-stroke brain injury and sensory, motor, and cognitive behavioral deficits Inhibition of HIF prolyl-4-hydroxylases by FG-4497 reduces brain tissue injury and edema formation during ischemic stroke.Inhibition of HIF-prolyl-4-hydroxylases prevents mitochondrial impairment and cell death in a model of neuronal oxytosis.Synthesis of a FTO inhibitor with anticonvulsant activity.Role of Hypoxia Inducible Factor 1 in Hyperglycemia-Exacerbated Blood-Brain Barrier Disruption in Ischemic Stroke.GSK-3β Inhibition Induced Neuroprotection, Regeneration, and Functional Recovery After Intracerebral Hemorrhagic Stroke.2-Methoxyestradiol confers neuroprotection and inhibits a maladaptive HIF-1α response after traumatic brain injury in mice.A role for prolyl hydroxylase domain proteins in hippocampal synaptic plasticity.Donor Treatment With a Hypoxia-Inducible Factor-1 Agonist Prevents Donation After Cardiac Death Liver Graft Injury in a Rat Isolated Perfusion Model.Intranasally Delivered Wnt3a Improves Functional Recovery after Traumatic Brain Injury by Modulating Autophagic, Apoptotic and Regenerative Pathways in the Mouse Brain.Regulation of therapeutic hypothermia on inflammatory cytokines, microglia polarization, migration and functional recovery after ischemic stroke in mice.

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Inhibition of prolyl hydroxylases by dimethyloxaloylglycine after stroke reduces ischemic brain injury and requires hypoxia inducible factor-1α.

http://www.wikidata.org/entity/Q34068989

description

2011 nî lūn-bûn

@nan

2011 թուականի Հոկտեմբերին հրատարակուած գիտական յօդուած

@hyw

2011 թվականի հոտեմբերին հրատարակված գիտական հոդված

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2011年の論文

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2011年論文

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2011年論文

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2011年論文

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2011年論文

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2011年論文

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2011年论文

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name

Inhibition of prolyl hydroxyla ...... s hypoxia inducible factor-1α.

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Inhibition of prolyl hydroxyla ...... s hypoxia inducible factor-1α.

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Inhibition of prolyl hydroxyla ...... s hypoxia inducible factor-1α.

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type

label

Inhibition of prolyl hydroxyla ...... s hypoxia inducible factor-1α.

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Inhibition of prolyl hydroxyla ...... s hypoxia inducible factor-1α.

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Inhibition of prolyl hydroxyla ...... s hypoxia inducible factor-1α.

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prefLabel

Inhibition of prolyl hydroxyla ...... s hypoxia inducible factor-1α.

@ast

Inhibition of prolyl hydroxyla ...... s hypoxia inducible factor-1α.

@en

Inhibition of prolyl hydroxyla ...... s hypoxia inducible factor-1α.

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J.NBD.2011.10.020

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Neurobiology of Disease

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Inhibition of prolyl hydroxyla ...... s hypoxia inducible factor-1α.

@en

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Alyssa R Espinera

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Ling Wei

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Molly E Ogle

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Xiaohuan Gu

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P2860

HIFalpha targeted for VHL-mediated destruction by proline hydroxylation: implications for O2 sensing

C. elegans EGL-9 and mammalian homologs define a family of dioxygenases that regulate HIF by prolyl hydroxylation

A conserved family of prolyl-4-hydroxylases that modify HIF

Selective inhibition of hypoxia-inducible factor (HIF) prolyl-hydroxylase 1 mediates neuroprotection against normoxic oxidative death via HIF- and CREB-independent pathways

General involvement of hypoxia-inducible factor 1 in transcriptional response to hypoxia

Activation of vascular endothelial growth factor gene transcription by hypoxia-inducible factor 1

Targeting of HIF-alpha to the von Hippel-Lindau ubiquitylation complex by O2-regulated prolyl hydroxylation

Ischemic cell death in brain neurons

Cellular and developmental control of O2 homeostasis by hypoxia-inducible factor 1 alpha

Hypoxia induces type II NOS gene expression in pulmonary artery endothelial cells via HIF-1

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733-742

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10.1016/J.NBD.2011.10.020

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2

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45

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2011-10-29T00:00:00Z

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22061780

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3286647

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