Notch signaling in the development of the inner ear: lessons from Drosophila.
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Is there a role for Notch signalling in human breast cancer?Brn3c null mutant mice show long-term, incomplete retention of some afferent inner ear innervationThe Notch ligand JAG1 is required for sensory progenitor development in the mammalian inner earEarly development of the vertebrate inner earSegregating neural and mechanosensory fates in the developing ear: patterning, signaling, and transcriptional control.Notch signaling and proneural genes work together to control the neural building blocks for the initial scaffold in the hypothalamusWhere hearing starts: the development of the mammalian cochleaBmp4 is essential for the formation of the vestibular apparatus that detects angular head movementsRegeneration of Sensory Hair Cells Requires Localized Interactions between the Notch and Wnt Pathways.An expanded Notch-Delta model exhibiting long-range patterning and incorporating MicroRNA regulationDelta1 expression, cell cycle exit, and commitment to a specific secretory fate coincide within a few hours in the mouse intestinal stem cell systemHey2 regulation by FGF provides a Notch-independent mechanism for maintaining pillar cell fate in the organ of CortiHey2 functions in parallel with Hes1 and Hes5 for mammalian auditory sensory organ developmentNotch promotes epithelial-mesenchymal transition during cardiac development and oncogenic transformationSignaling and Transcription Factors during Inner Ear Development: The Generation of Hair Cells and Otic Neurons.Changes in the regulation of the Notch signaling pathway are temporally correlated with regenerative failure in the mouse cochleaInner ear supporting cells: rethinking the silent majority.In vivo visualization of Notch1 proteolysis reveals the heterogeneity of Notch1 signaling activity in the mouse cochlea.Notch signaling and Atoh1 expression during hair cell regeneration in the mouse utricle.Notch signaling specifies prosensory domains via lateral induction in the developing mammalian inner earHair cell recovery in mitotically blocked cultures of the bullfrog saccule.Numb is not a critical regulator of Notch-mediated cell fate decisions in the developing chick inner ear.Lineage tracing of Sox2-expressing progenitor cells in the mouse inner ear reveals a broad contribution to non-sensory tissues and insights into the origin of the organ of Corti.Basic helix-loop-helix gene Hes6 delineates the sensory hair cell lineage in the inner ear.Shaping the mammalian auditory sensory organ by the planar cell polarity pathway.Activated notch causes deafness by promoting a supporting cell phenotype in developing auditory hair cells.Patent ductus arteriosus in mice with smooth muscle-specific Jag1 deletion.Conditional deletion of pten leads to defects in nerve innervation and neuronal survival in inner ear development.Planar cell polarity in the inner ear: how do hair cells acquire their oriented structure?The Notch ligand Jagged1 is required for inner ear sensory development.Notch signaling alters sensory or neuronal cell fate specification of inner ear stem cells.The Rho GTPase Cdc42 regulates hair cell planar polarity and cellular patterning in the developing cochlea.Molecular conservation and novelties in vertebrate ear development.The Cell Adhesion Molecules Roughest, Hibris, Kin of Irre and Sticks and Stones Are Required for Long Range Spacing of the Drosophila Wing Disc Sensory SensillaIn vivo Notch reactivation in differentiating cochlear hair cells induces Sox2 and Prox1 expression but does not disrupt hair cell maturation.Overactivation of Notch1 signaling induces ectopic hair cells in the mouse inner ear in an age-dependent manner.Jagged1 and Notch1 help edit M cell patterning in Peyer's patch follicle epitheliumMutant mice reveal the molecular and cellular basis for specific sensory connections to inner ear epithelia and primary nuclei of the brain.Neural crest cell-autonomous roles of fibronectin in cardiovascular development.Notch signaling during cell fate determination in the inner ear.
P2860
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P2860
Notch signaling in the development of the inner ear: lessons from Drosophila.
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2000 nî lūn-bûn
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2000 թուականի Հոկտեմբերին հրատարակուած գիտական յօդուած
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2000 թվականի հոտեմբերին հրատարակված գիտական հոդված
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2000年の論文
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2000年論文
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Notch signaling in the development of the inner ear: lessons from Drosophila.
@ast
Notch signaling in the development of the inner ear: lessons from Drosophila.
@en
Notch signaling in the development of the inner ear: lessons from Drosophila.
@nl
type
label
Notch signaling in the development of the inner ear: lessons from Drosophila.
@ast
Notch signaling in the development of the inner ear: lessons from Drosophila.
@en
Notch signaling in the development of the inner ear: lessons from Drosophila.
@nl
prefLabel
Notch signaling in the development of the inner ear: lessons from Drosophila.
@ast
Notch signaling in the development of the inner ear: lessons from Drosophila.
@en
Notch signaling in the development of the inner ear: lessons from Drosophila.
@nl
P2093
P2860
P356
P1476
Notch signaling in the development of the inner ear: lessons from Drosophila.
@en
P2093
P2860
P304
11692-11699
P356
10.1073/PNAS.97.22.11692
P407
P577
2000-10-01T00:00:00Z