The ATM-p53 pathway suppresses aneuploidy-induced tumorigenesis - Wikidata - awgldk - TriplyDB

The ATM-p53 pathway suppresses aneuploidy-induced tumorigenesis

The ATM-p53 pathway suppresses aneuploidy-induced tumorigenesis

http://www.wikidata.org/entity/Q34069561

about

Ubiquitylation of autophagy receptor Optineurin by HACE1 activates selective autophagy for tumor suppression DNA damage associated with mitosis and cytokinesis failure Mitotic Spindle Disruption by Alternating Electric Fields Leads to Improper Chromosome Segregation and Mitotic Catastrophe in Cancer Cells.Replication stress in Mammalian cells and its consequences for mitosis Mitochondrial genomic variation associated with higher mitochondrial copy number: the Cache County Study on Memory Health and Aging Unique features of the transcriptional response to model aneuploidy in human cells BCL9L Dysfunction Impairs Caspase-2 Expression Permitting Aneuploidy Tolerance in Colorectal Cancer Reprogramming to pluripotency can conceal somatic cell chromosomal instability Chromosome missegregation rate predicts whether aneuploidy will promote or suppress tumors.Ploidy variation in multinucleate cells changes under stress.Tumor suppressor roles of CENP-E and Nsl1 in Drosophila epithelial tissues.Mechanisms and consequences of aneuploidy and chromosome instability in the aging brain Quantitative proteomic analysis reveals posttranslational responses to aneuploidy in yeast.ATM signalling and cancer.ATM activation in the presence of oxidative stress.The viral restriction factor tetherin prevents leucine-rich pentatricopeptide repeat-containing protein (LRPPRC) from association with beclin 1 and B-cell CLL/lymphoma 2 (Bcl-2) and enhances autophagy and mitophagy.Absence of Wip1 partially rescues Atm deficiency phenotypes in mice.Autophagy enhanced by microtubule- and mitochondrion-associated MAP1S suppresses genome instability and hepatocarcinogenesis Aneuploidy and chromosomal instability in cancer: a jackpot to chaos.Key role of dual specificity kinase TTK in proliferation and survival of pancreatic cancer cells.Losing balance: the origin and impact of aneuploidy in cancer Linking stem cells to chromosomal instability.Whole Genome Pathway Analysis Identifies an Association of Cadmium Response Gene Loss with Copy Number Variation in Mutant p53 Bearing Uterine Endometrial Carcinomas.Caspase-2 deficiency promotes aberrant DNA-damage response and genetic instability.Transcriptional consequences of aneuploidy.Genetic and pharmacological inhibition of TTK impairs pancreatic cancer cell line growth by inducing lethal chromosomal instability.Aneuploidy-induced delaminating cells drive tumorigenesis in Drosophila epithelia.Identification of aneuploidy-selective antiproliferation compounds.Whole chromosome aneuploidy in the brain of Bub1bH/H and Ercc1-/Δ7 mice.Aneuploidy in health, disease, and aging.The investigational Aurora kinase A inhibitor MLN8237 induces defects in cell viability and cell-cycle progression in malignant bladder cancer cells in vitro and in vivo.Tetraploid cells produced by absence of substrate adhesion during cytokinesis are limited in their proliferation and enter senescence after DNA replication Aneuploidy and tumorigenesis.Fast clearance of lipid droplets through MAP1S-activated autophagy suppresses clear cell renal cell carcinomas and promotes patient survival Negative Selection and Chromosome Instability Induced by Mad2 Overexpression Delay Breast Cancer but Facilitate Oncogene-Independent Outgrowth.Aneuploidy impairs hematopoietic stem cell fitness and is selected against in regenerating tissues in vivo High rates of chromosome missegregation suppress tumor progression but do not inhibit tumor initiation.2n or not 2n: Aneuploidy, polyploidy and chromosomal instability in primary and tumor cells.Autophagy defects suggested by low levels of autophagy activator MAP1S and high levels of autophagy inhibitor LRPPRC predict poor prognosis of prostate cancer patients.Catastrophic nuclear envelope collapse in cancer cell micronuclei.

P2860

Q24300797-3BB0A69F-3400-41CF-98E6-EE5CF3854C1C Q26991874-1051557A-43F5-41D5-82A0-DFFE07FF2B8E Q27303864-A05D783A-B58C-40E0-9F07-CE6A32CC0504 Q28087011-680DFE6C-3ED1-421F-85D6-3954703E481A Q28390920-FDBE013E-1A63-4BA0-8B78-BB20D465961D Q28396449-3D694F3D-1778-4C08-A7D4-A3EC7B92ED8D Q28468367-E2B1EA80-33B6-4BBE-A1D8-23C094F8376C Q28483105-AEACF3B3-2D44-42CC-8961-27249982F1BB Q30556712-708A2B31-0426-4642-A600-57100AE5FAC1 Q30627170-A154AB09-0823-443C-855C-3089A44C3109 Q33728905-9F08472E-8040-4012-A306-B346DBAD496F Q33850635-B4F291C5-266B-48B9-8FB5-4CB0390A5A0D Q34030887-01DFC892-85CB-4931-AA93-6CBA1116AB65 Q34357377-D2022C54-2E16-400A-90D1-2C334C7FC124 Q34619774-82B58C39-90C8-437D-9FCB-AA4B5F5863B6 Q35172704-9A2BE895-206A-4D84-9069-A10DB8F2DD8D Q35403658-09F3E1E5-82B7-4E01-9AC6-509880415D00 Q35624230-3C42D5E0-A160-40DE-B538-968D18DCDD9F Q35646101-E6F463B6-3154-4DEF-944F-17285CCB953D Q35678047-FB6C09A2-1990-4FBF-893F-51AD85885E9C Q36008297-0A829C0B-82A0-4284-80C5-5A65147AE3EA Q36038443-2C37402D-BA9B-41B9-AF3C-4E3CECBB3A58 Q36071143-D8315F32-8B3A-40F5-848D-5D66DDB8F215 Q36084491-77A6BF36-79E4-49D9-B370-F27ADD4A8A72 Q36140289-269458B0-2DC0-4633-B0C1-F3A8CA976A49 Q36336091-2E51B406-C084-4A44-A303-1C5918BA51FC Q36483559-2503DC2B-1913-4873-8F42-1A3147084E9E Q36493649-BC1B9D2E-6BDE-422F-A4F3-79EB838AEF41 Q36551296-45C12915-DA60-405B-9830-C6E42B19CD91 Q36732750-9D8FDE5A-F80A-4F76-9C2E-BD25BBBA5B2B Q36765779-5FA8A45A-6D02-467D-8DEA-DCEC1C3CEE0E Q36781670-0B953EA6-CDFA-4442-8C40-FA8DD87E521D Q36837323-C3EF8C83-8E32-4013-8F46-F6BF8898CEDB Q36905895-EF52D3B9-2B01-4182-BEFE-9175FB4D655D Q37037781-B1557F20-A3F7-4EBC-A335-7E9EB1389C99 Q37051745-B66893C1-FFDC-400B-8083-D8C2DA4112D0 Q37052716-5C71BAE6-4A7F-4705-A7F5-B5C7A0C7923A Q37078688-6BE73E1F-CB50-4205-8D60-653EEDE77C33 Q37087035-06185CDC-781B-4B2F-8DA9-14A6FAB8AA50 Q37111701-CE288CD3-E6B1-4B7A-A617-A77635AE8AC9

P2860

The ATM-p53 pathway suppresses aneuploidy-induced tumorigenesis

http://www.wikidata.org/entity/Q34069561

description

2010 nî lūn-bûn

@nan

2010 թուականի Յուլիսին հրատարակուած գիտական յօդուած

@hyw

2010 թվականի հուլիսին հրատարակված գիտական հոդված

@hy

2010年の論文

@ja

2010年論文

@yue

2010年論文

@zh-hant

2010年論文

@zh-hk

2010年論文

@zh-mo

2010年論文

@zh-tw

2010年论文

@wuu

name

The ATM-p53 pathway suppresses aneuploidy-induced tumorigenesis

@ast

The ATM-p53 pathway suppresses aneuploidy-induced tumorigenesis

@en

The ATM-p53 pathway suppresses aneuploidy-induced tumorigenesis

@nl

type

label

The ATM-p53 pathway suppresses aneuploidy-induced tumorigenesis

@ast

The ATM-p53 pathway suppresses aneuploidy-induced tumorigenesis

@en

The ATM-p53 pathway suppresses aneuploidy-induced tumorigenesis

@nl

prefLabel

The ATM-p53 pathway suppresses aneuploidy-induced tumorigenesis

@ast

The ATM-p53 pathway suppresses aneuploidy-induced tumorigenesis

@en

The ATM-p53 pathway suppresses aneuploidy-induced tumorigenesis

@nl

P1433

Q34069561-61228D20-F21C-4F5A-B079-B4922AFF30E2

P1476

Q34069561-44A876A7-4C10-41E8-8571-B3F8796B278B

P2093

Q34069561-1D9C8680-9BC8-47A4-AEAA-A55AFB8C9115

Q34069561-22ED23E3-0752-4F03-A0F2-8FEC1663C850

Q34069561-2DA5AD74-1F45-4DA5-974E-DE91C49BABAA

Q34069561-60D91D04-75AB-4FFD-8315-65F4F9F3761C

Q34069561-655B458F-50E8-46BB-8B5C-B9C675759D82

Q34069561-8ADD3DBA-F6F0-4CF1-A74D-F0C9E6B1B42C

Q34069561-C0271AD5-CDB3-406A-8C13-B6AAC2903428

Q34069561-C84694C5-40CA-4AE9-ABCC-952574CEA93A

Q34069561-CB701614-9210-491A-94AD-A2E85E39E34D

P2860

Q34069561-074A6C1A-89F4-437E-9372-3058D22484A1

Q34069561-0C716F05-AF4B-40D7-8417-0FD936A97AAF

Q34069561-121778C9-9E39-4A41-88B3-C1073D0AB4B4

Q34069561-3547F4BF-BB75-4D83-9F6C-5305E87AE192

Q34069561-35B8F0E8-E71C-420B-BAD9-B4072136194D

Q34069561-370B93AE-1CFD-4190-A506-578ADC1B1039

Q34069561-3CADEBE2-F069-42B9-A6FB-8CA24F122DC5

Q34069561-42149EA2-3055-465D-B861-4D5F4A0355CF

Q34069561-53F53C95-179C-4B14-B8C8-D837DE436836

Q34069561-59411BC0-008C-4A29-B2D4-5665F6F3FB30

P304

Q34069561-77B34E3D-8A01-411D-A10B-4F22D3FC0576

P31

Q34069561-358310BE-7FFA-41B8-A828-C27638C0EBFF

P356

Q34069561-6E7CE6BE-9763-4613-B646-C4B56FB1DCC1

P407

Q34069561-4428424A-484B-4AF5-940A-7ED90736167F

P433

Q34069561-F1E240C1-0CA2-41E8-B15C-61BD77646570

P478

Q34069561-AE8265EF-AAF3-4740-A15A-8A3977A72615

P577

Q34069561-C3284DF7-1C32-4858-AB86-AC97895E1C77

P5875

Q34069561-3EA5B969-1F0D-46E3-A91B-9C8BB1AA27EF

P698

Q34069561-1A088F56-F2BA-47D9-886D-680D2CAA3036

P932

Q34069561-1A3F8D27-C94C-4A30-90E7-A70EA06F72BF

P356

PNAS.1005960107

P1433

Proceedings of the National Academy of Sciences of the United States of America

P1476

The ATM-p53 pathway suppresses aneuploidy-induced tumorigenesis

@en

P2093

Darren J Baker

http://www.w3.org/2001/XMLSchema#string

Jan M van Deursen

http://www.w3.org/2001/XMLSchema#string

Linjie Guo

http://www.w3.org/2001/XMLSchema#string

Min Li

http://www.w3.org/2001/XMLSchema#string

Pumin Zhang

http://www.w3.org/2001/XMLSchema#string

Shuhua Han

http://www.w3.org/2001/XMLSchema#string

Xiao Fang

http://www.w3.org/2001/XMLSchema#string

Xue Gao

http://www.w3.org/2001/XMLSchema#string

Zhubo Wei

http://www.w3.org/2001/XMLSchema#string

P2860

Aneuploidy affects proliferation and spontaneous immortalization in mammalian cells

Bub1 mediates cell death in response to chromosome missegregation and acts to suppress spontaneous tumorigenesis

The spindle-assembly checkpoint in space and time

Feedback control of mitosis in budding yeast

Identification of a vertebrate sister-chromatid separation inhibitor involved in transformation and tumorigenesis

How proteolysis drives the cell cycle

MAD2 haplo-insufficiency causes premature anaphase and chromosome instability in mammalian cells

Genetic instability in colorectal cancers

Atm-deficient mice: a paradigm of ataxia telangiectasia

A 20S complex containing CDC27 and CDC16 catalyzes the mitosis-specific conjugation of ubiquitin to cyclin B

P304

14188-14193

http://www.w3.org/2001/XMLSchema#string

P31

scholarly article

P356

10.1073/PNAS.1005960107

http://www.w3.org/2001/XMLSchema#string

P407

P433

32

http://www.w3.org/2001/XMLSchema#string

P478

107

http://www.w3.org/2001/XMLSchema#string

P577

2010-07-27T00:00:00Z

http://www.w3.org/2001/XMLSchema#dateTime

P5875

45388912

http://www.w3.org/2001/XMLSchema#string

P698

20663956

http://www.w3.org/2001/XMLSchema#string

P932

2922543

http://www.w3.org/2001/XMLSchema#string