eIF4E phosphorylation promotes tumorigenesis and is associated with prostate cancer progression. - Wikidata - awgldk - TriplyDB

eIF4E phosphorylation promotes tumorigenesis and is associated with prostate cancer progression.

eIF4E phosphorylation promotes tumorigenesis and is associated with prostate cancer progression.

http://www.wikidata.org/entity/Q34069836

about

Essential role for Mnk kinases in type II interferon (IFNgamma) signaling and its suppressive effects on normal hematopoiesis Translational Control during Calicivirus Infection Regulation of global and specific mRNA translation by the mTOR signaling pathway Signalling to eIF4E in cancer Positive mRNA Translational Control in Germ Cells by Initiation Factor Selectivity Mnk kinase pathway: Cellular functions and biological outcomes MYC cooperates with AKT in prostate tumorigenesis and alters sensitivity to mTOR inhibitors Structural Analysis of the DAP5 MIF4G Domain and Its Interaction with eIF4A Flavivirus Infection Uncouples Translation Suppression from Cellular Stress Responses A novel mouse model for inhibition of DOHH-mediated hypusine modification reveals a crucial function in embryonic development, proliferation and oncogenic transformation The Distribution of eIF4E-Family Members across Insecta Cotargeting MNK and MEK kinases induces the regression of NF1-mutant cancers Adenosine Monophosphate-activated Protein Kinase (AMPK) Activators For the Prevention, Treatment and Potential Reversal of Pathological Pain.Investigating the consequences of eIF4E2 (4EHP) interaction with 4E-transporter on its cellular distribution in HeLa cells Translational control of the activation of transcription factor NF-κB and production of type I interferon by phosphorylation of the translation factor eIF4E.Phosphorylation of mTOR and S6RP predicts the efficacy of everolimus in patients with metastatic renal cell carcinoma.New frontiers in translational control of the cancer genome Genetic removal of matrix metalloproteinase 9 rescues the symptoms of fragile X syndrome in a mouse model.Simultaneous inhibition of mTOR-containing complex 1 (mTORC1) and MNK induces apoptosis of cutaneous T-cell lymphoma (CTCL) cells.Mnk earmarks eIF4E for cancer therapy.Modulation of mTOR effector phosphoproteins in blood basophils from allergic patients The cancerous translation apparatus Eukaryotic initiation factor 4F: a vulnerability of tumor cells.On the Diversification of the Translation Apparatus across Eukaryotes eIF4E is an important determinant of adhesion and pseudohyphal growth of the yeast S. cerevisiae.Mitogen-activated protein kinase-interacting kinase regulates mTOR/AKT signaling and controls the serine/arginine-rich protein kinase-responsive type 1 internal ribosome entry site-mediated translation and viral oncolysis.Pharmacogenetic inhibition of eIF4E-dependent Mmp9 mRNA translation reverses fragile X syndrome-like phenotypes.Differential expression of S6K2 dictates tissue-specific requirement for S6K1 in mediating aberrant mTORC1 signaling and tumorigenesis.Targeting the eIF4F translation initiation complex: a critical nexus for cancer development Phosphorylated Mnk1 and eIF4E are associated with lymph node metastasis and poor prognosis of nasopharyngeal carcinoma.Murine norovirus 1 (MNV1) replication induces translational control of the host by regulating eIF4E activity during infection MNK1-induced eIF-4E phosphorylation in myeloma cells: a pathway mediating IL-6-induced expansion and expression of genes involved in metabolic and proteotoxic responses Phosphorylation of eIF4E Confers Resistance to Cellular Stress and DNA-Damaging Agents through an Interaction with 4E-T: A Rationale for Novel Therapeutic Approaches.RSK regulates activated BRAF signalling to mTORC1 and promotes melanoma growth Effect of Orexin-A on Cortisol Secretion in H295R Cells via p70S6K/4EBP1 Signaling Pathway.Light-regulated translational control of circadian behavior by eIF4E phosphorylation.YB-1 and MTA1 protein levels and not DNA or mRNA alterations predict for prostate cancer recurrence Differential Requirements for eIF4E Dose in Normal Development and Cancer Emerging therapeutics targeting mRNA translation Characterization of MNK1b DNA Aptamers That Inhibit Proliferation in MDA-MB231 Breast Cancer Cells

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eIF4E phosphorylation promotes tumorigenesis and is associated with prostate cancer progression.

http://www.wikidata.org/entity/Q34069836

description

2010 nî lūn-bûn

@nan

2010 թուականի Օգոստոսին հրատարակուած գիտական յօդուած

@hyw

2010 թվականի օգոստոսին հրատարակված գիտական հոդված

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2010年の論文

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2010年論文

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2010年論文

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2010年論文

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2010年論文

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2010年論文

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2010年论文

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name

eIF4E phosphorylation promotes ...... h prostate cancer progression.

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eIF4E phosphorylation promotes ...... h prostate cancer progression.

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eIF4E phosphorylation promotes ...... h prostate cancer progression.

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type

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eIF4E phosphorylation promotes ...... h prostate cancer progression.

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eIF4E phosphorylation promotes ...... h prostate cancer progression.

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eIF4E phosphorylation promotes ...... h prostate cancer progression.

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eIF4E phosphorylation promotes ...... h prostate cancer progression.

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eIF4E phosphorylation promotes ...... h prostate cancer progression.

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eIF4E phosphorylation promotes ...... h prostate cancer progression.

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PNAS.1005320107

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Proceedings of the National Academy of Sciences of the United States of America

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eIF4E phosphorylation promotes ...... h prostate cancer progression.

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P2093

Andrea Brueschke

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Emmanuel Petroulakis

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Fred Saad

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Ismaël Hervé Koumakpayi

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Kaori Yoshida

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Liwei Rong

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Louis A Gaboury

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Michael Pollak

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P2860

Active-site inhibitors of mTOR target rapamycin-resistant outputs of mTORC1 and mTORC2

MNK1, a new MAP kinase-activated protein kinase, isolated by a novel expression screening method for identifying protein kinase substrates

Mitogen-activated protein kinases activate the serine/threonine kinases Mnk1 and Mnk2

Human eukaryotic translation initiation factor 4G (eIF4G) recruits mnk1 to phosphorylate eIF4E

Phosphorylation of the cap-binding protein eukaryotic translation initiation factor 4E by protein kinase Mnk1 in vivo

Structural and functional identification of two human, tumor-derived monocyte chemotactic proteins (MCP-2 and MCP-3) belonging to the chemokine family

Pten dose dictates cancer progression in the prostate

eIF4 initiation factors: effectors of mRNA recruitment to ribosomes and regulators of translation

ONCOMINE: a cancer microarray database and integrated data-mining platform

Elevated sensitivity to diet-induced obesity and insulin resistance in mice lacking 4E-BP1 and 4E-BP2

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14134-14139

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10.1073/PNAS.1005320107

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32

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107

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Nathaniel Robichaud

Pier Paolo Pandolfi

Nahum Sonenberg

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2010-08-02T00:00:00Z

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45461347

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20679199

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phosphorylation

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